Term
| TRH stimulates secretion of... |
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Definition
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Term
| PRL secretion is increased by... |
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Definition
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Term
| What stimulates ACTH secretion? |
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Definition
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Term
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Definition
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Term
| definition of poikilothermia |
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Definition
| body temperature varies with environmental temperature |
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Term
| deletion of genes on paternal chromosome 15; dx? |
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Definition
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Term
| hypogonadism, obesity of subcutaneous fat; dx? |
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Definition
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Term
| obesity and retinal pigmentosa; dx? |
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Definition
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Term
| the hypothalamus surrounds the ___ ventricle |
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Definition
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Term
| posterior pituitary secretes... |
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Definition
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Term
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Definition
| insulin resistance, lipolysis, IGF-1 production |
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Term
| levels of GH is highest at ___ and ___ in a person's lifetime |
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Definition
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Term
| stress and sleep [increases/decreases] GH |
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Definition
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Term
| DM, anorexia nervosa, renal failure, and liver failure [increase/decrease] GH |
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Definition
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Term
| serotonin [increases/decreases] PRL |
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Definition
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Term
| what is the first abnormality to occur in ACTH-secreting pituitary tumors? |
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Definition
| loss of circadian regulation |
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Term
| inhibin is produced by ___ and inhibits ___ |
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Definition
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Term
| GnRH is used clinically for...(3) |
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Definition
| medical castration, amenorrhea, metastatic prostate cancer |
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Term
| goiter formation requires... |
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Definition
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Term
| estrogen [increases/decreases] cortisol binding globulin |
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Definition
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Term
| hot flashes are seen in [primary/secondary] gonadal failure |
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Definition
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Term
| how does PRL inhibit LH release? |
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Definition
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Term
| effect of PRL on testosterone |
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Definition
| PRL decreases testosterone |
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Term
| what is the pathogenesis of a pt with primary hypothyroidism and his presenting complaint of galactorrhea? |
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Definition
| low T3/T4 -> high TSH, high TRH; TRH -> PRL -> galactorrhea |
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Term
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Definition
| dopamine agonist; tx for PRL tumors |
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Term
| what test is used for screening for Cushing's syndrome? |
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Definition
| overnight dexamethasone test |
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Term
| metabolically, GH is similar to [insulin/glucagon] |
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Definition
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Term
| surgery for acromegaly pituitary tumor is curative in __% of pts |
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Definition
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Term
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Definition
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Term
| differential for hypotonic polyuria |
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Definition
1. drinking a lot of water (primary)
2. central diabetes insipidus
3. nephrogenic diabetes insipidus |
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Term
| 3 forms of hereditary diabetes insipidus |
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Definition
1. autosomal dominant central DI: vasopressin mutation
2. X-linked nephrogenic DI: vasopressin receptor mutation
3. autosomal recessive nephrogenic DI: aquaporin-2 mutation |
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Term
| hypotonic polyuria without polydypsia; dx? |
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Definition
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Term
| pt in motor vehicle accident shows signs of SIADH; dx? |
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Definition
| triphasic diabetes insipidus |
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Term
| pathogenesis of triphasic diabetes insipidus |
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Definition
| acute injury to posterior pituitary causes release of ADH from storage -> hyponatremia; when stores are depleted, ADH secretion falls -> hypotonic polyuria polydypsia = diabetes insipidus |
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Term
| tx for central diabetes insipidus |
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Definition
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Term
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Definition
| diuretics (to tx hypernatremia, not polyuria) |
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