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Details

Hypertension Rx
Recommendations and Indications
20
Pharmacology
Graduate
10/06/2010

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Cards

Term
Normal Blood Pressure
Definition
<120 and <80
Term
Prehypertension
Definition
120-139 or 80-89
Term
Stage 1 Hypertension
Definition
140-159 or 90-99
Term
Stage 2 Hypertension
Definition
≥160 or ≥100
Term
Goals of HTN therapy
Definition
Reduce CVD and renal morbidity and mortality; Achieve SBP goal
Term
Blood Pressure Goal in Uncomplicated HTN
Definition
<140/90
Term
Blood Pressure Goal for patients with diabetes, renal disease, carotid artery disease, peripheral artery disease, abdominal aortic aneurysm, left ventricular dysfunction
Definition
<130/80 (Consider <120/80 for left ventricular dysfunction)
Term
The Big 5 Lifestyle Modifications
Definition
Weight reduction, DASH, Dietary sodium restriction, physical activity, moderate alcohol consumption
Term
Initial Drug Therapy (class/general) for Stage 1 HTN
Definition
Thiazide diuretics for most (may consider ACEI, ARB, CCB or combo)
Term
Initial Drug Therapy (class/general) for Stage 2 HTN
Definition
Two-drug combination for most (usually thiazide diuretic + ACEI, ARB or CCB)
Term
Which HTN med is useful in slowing demineralization in osteoporosis?
Definition
Thiazide-type diuretics
Term
Which HTN med is useful in the treatment of atrial tachyarrhythmias/fibrillation, migraines, thyrotoxicosis, essential tremor or perioperative HTN?
Definition
Beta Blocker
Term
Which HTN med is useful with Raynaud's syndrome and certain arrhythmias?
Definition
CCB (Calcium Antagonist)
Term
Which HTN med is useful in prostatism/benign prostate hypertrophy (BPH)
Definition
Alpha-blockers
Term
Which HTN med should be use cautiously in gout or a history of significant hyponatremia?
Definition
Thiazide diuretic
Term
Which HTN med should be avoided in patients with asthma, reactive airways disease, or second- or third- degree heart blocks?
Definition
Beta Blockers
Term
Which HTN meds are contraindicated in pregnant women or those likely to become pregnant?
Definition
ACEI and ARB
Term
Which HTN med should not be used in individuals with a history of angioedema?
Definition
ACEIs
Term
Which HTN meds can cause hyperkalemia?
Definition
Aldosterone antagonists and potassium-sparing diuretics
Term
What should you use caution with in elderly patients?
Definition
Orthostasis: start with low antiHTN dose to minimize orthostasis, especially with diuretics and ACEI
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