Term
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Definition
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Term
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Definition
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Term
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Definition
| Allergic asthma, allergic rhinitis(hay fever), food allergies |
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Term
| Manifestations of Type 1? |
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Definition
| Hypotension, wheezing, GI or uterine spasm, stridor and urticaria |
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Term
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Definition
| Acute glomerulonephritis and serum sickness, SLE, RA |
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Term
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Definition
| urticaria, fever, and joint pain |
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Term
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Definition
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Term
| How does type 4 differ from other hypersensitivity? |
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Definition
1. Cell mediated immune responses, and involve T cells of iummune system
2. Delayed 24-48 hours after exposure |
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Term
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Definition
Contact dermatitis
TB skin test
Graft vs host disease |
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Term
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Definition
| Reaction to proteins in antiserum derived from animals |
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Term
| Manifestations of serum sickness? |
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Definition
Develop 2 weeks after exposure(PNC)
Rash, pruritus, arthralgia, fever, lymphadenopathy, hypotension, splenomegaly, glomerulonephritis, or proteinuria |
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Term
| Manifestations of acute graft vs host disease? |
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Definition
first 100 days after transplant
pruritic macular papular rast
begins on extremities and progesses to trunk
nausea vomiting anorexia diarrhea cramping abdominal paind and impaired liver function |
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Term
| Manifestations of chronic graft vs host disease? |
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Definition
After first 100 days
Recurrent infections
skin reactions
thromocytopenia
mouth throat and asophageal ulcers
GI disorders
cholestasis
eye irritation |
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Term
| Allergic rhinitis manifestions? |
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Definition
| rhinorrhya, watery eyes, itchy throat, hives, sore throat, nasal congestion and headache |
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Term
| Allergic asthma manifestations? |
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Definition
Bronchoconstriction and airway inflammation
"Elephant is sitting on my chest" |
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Term
| WBC w/ dfferential will detect ___ levels of ______. |
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Definition
| High, eosinophils. Normally 1-4% of WBCs. |
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Term
| Radioallergosorbent test (RAST) |
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Definition
| Test results are compared with control values and used to identify hypersensitivities. Does not indicate the specific allergen olny the tendency to have allergic responses. A normal level of IgE for adults is 39 IU/ml (or <100 IU/mL) increases with allergies. |
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Term
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Definition
| the clients serum is mixed with the donor's RBCs. If the clients serum contains antibodies to an RBC antigen agglutination will occur. This is called a positive response. The normal value is negative. Used to determine is client will have a reaction to blood transfusion. |
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Term
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Definition
| huge antibody, antigen, and complement proteins interact to form massive complexes |
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Term
| Antihistamines are not effective |
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Definition
| in relieving asthmatic responses to allergens and mya worsen symptoms by their drying effect of respiratory secretions. |
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Term
| Antihistamines side effects? |
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Definition
| Drowsiness/sedation and dry mouth |
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Term
| Cromolyn sodium (Intal, NasalCrom) used to treat |
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Definition
| Prevention ofallergic rhinitis and asthma. Not acute episode. Mast cell stabilizing durg |
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Term
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Definition
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Term
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Definition
| Immediate treatment for anaphylaxis has vasoconstricing and bronchodilating effects |
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Term
| HOw much subcutaneous epinephrine? |
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Definition
| 1:1000, 0.3-0.5mL may be repeated 20-30 minutes |
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Term
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Definition
| Place tourniquet above the site and infiltrate the site with epinephrine as prescribed |
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Term
| RIST- radioimmunosorbent test |
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Definition
| shows the blood level of IgE directed against a specific antigen and thus can determine specific allergies. Expensive |
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Term
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Definition
| causing vasoconstriction in the inflamed tissue, thereby reducing the edema |
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Term
| Teach what pts to consult with a doctor before taking any decongestant bc of systemic effects? |
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Definition
| Hypertension Glaucoma Urinary Retention |
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Term
| Type 1 respones occurs as a result |
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Definition
| of the histamine and mediator release, causing increased capillary permeability, bronchial constriction, vasodilation and smooth muscle contraction-which can lead to hypotension and impaired tissue perfusion aka anaphylactic shock |
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Term
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Definition
| antibodies bind to antigens on body cells |
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Term
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Definition
| Graves disease- autoantibody binds to TSH receptor sites on thyroid and keeps producing thyroid hormones continuously |
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Term
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Definition
Stimulatory reaction
Excess stimulation of normal cell surface receptor by autoantibody
results in continuous "turned on" cell state |
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Term
| Sjogren's syndrome manifestations? |
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Definition
Dry eyes, dry mucous membranes of nose and mouth (xerostomia) vaginal dryness
No tears cause inflammation/ulceration of cornea |
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Term
|
Definition
| autoimmune destruction of lacrimal, salivary and vaginal mucosal glands |
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Term
| Sjorgren's is often accompanied by |
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Definition
Fibromyalgia or RA
Women 35-45
Triggers are thought to be viral-HIV, HTLV and Epstein barr virus |
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Term
Goodpasture's syndrome is
and is treated w/? |
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Definition
autoantibodies made against glomerular basement membrane and neutrophils
Treat w/ high does corticosteroids |
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Term
| Goodpastures syndrome manifestations |
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Definition
SOB, hemoptysis, decreased urine output, weight gain, edema, hypertension, tachycardia
LUNG and KIDNEYS |
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