Term
| Altered immune response to an antigen that results in harm |
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Definition
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Term
| Hypersensitivity is classified by |
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Definition
| type of immune response, immune or delayed |
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Term
| Immiediate hypersensitivity responses |
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Definition
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Term
| antigen- lymphoctye reaction (delayed) |
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Definition
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Term
| Systemic hypersensitivity responses type I |
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Definition
| Type I anaphylaxis, urticaria, angioedema, rhinitis, conjunctivitis, bronchial |
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Term
| Type II systemic hypersensitivity reacion |
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Definition
transfusion reaction, A B O incompatibility, autoimmune anemia, neutropenia, anti-GM disease Immune complex-mediated reactions: vasculitis, arthritis, contact dermatitis |
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Term
| Examples of common hypersensitivity reactions |
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Definition
| allergic asthma, hay fever, hives |
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Term
| Common hypersensitiviy reactions are triggered when allergen interacts with free |
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Definition
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Term
| Initial symptoms of anaphylaxis |
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Definition
| rash/urticaria, shortness of breah/wheezing, stomach pain/nausea, facial swelling, fainting |
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Term
| Type II cytotoxic hypersensitivity may be stimulated by |
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Definition
| exogenous antigen ( foreign tissue cells) |
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Term
| Results from formation of IgG or IgM antibody–antigen immune complexes in circulatory system |
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Definition
| Type III (Immune complex-mediated) hypersensitivity |
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Term
| Immune complexes accumulate at specific site |
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Definition
| Type III hypersensitivity |
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Term
| Type III hypersensitivity |
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Definition
| Immune complex mediated hypersensitivity |
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Term
| latex allergies are common in certain paitents |
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Definition
| spina bifida, congenital urologic, gastrointestinal, tracheosophageal defects, multiple surgeries, diabetes requiring insulin, history of atopy |
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Term
| latex allergy often coexists with alergy to certain foods including |
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Definition
| kiwi, bananas, tomatoes, avocados |
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Term
| Type I reaction manifestations |
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Definition
| Hypertension, Wheezing, GI Or Uterine Spasm, Strider, Urticaria And Anaphylaxis |
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Term
| Type II reaction manfistations ( tissue specific) |
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Definition
| Bearing Manifestations, Dyspnea, Fever |
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Term
| Type III reaction manifestations (immune mediated) |
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Definition
| urticaria, fever, joint pain |
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Term
| Type IV reaction manifestations |
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Definition
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Term
| Mild hypersensitivity responses clinical manifestations |
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Definition
| discomfort, fatigue, lasts hours to a few days, resolve by themselves or with over the counter treatment, allergic rhinits lasting beyone a day or two may reult in localized infection |
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Term
| clinical manifestations of moderate hypersensitivity reacions |
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Definition
| localized pin and inflammations, difficulty breathing, loss of smell, taste, appetite, skin reactions (urticaria, atopic and contact dermatitis) |
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Term
| Care of patient for type I reaction |
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Definition
| maintain airway and cardiac output |
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Term
| Care for the patient for type II reaction |
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Definition
| manage bleeding, renal failure |
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Term
| Care for the patient with type III reacion |
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Definition
| remove offending antigen, interrupt inflammatory response |
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Term
| Care for the paitent with Type IV reaction |
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Definition
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Term
| Diagnostic tests for hypersensitivity reactions |
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Definition
| WBCD – eosinophils often present with Type I, Radioallergosorbent test (RAST), Blood type & crossmatch, Indirect Coombs test, Direct Coombs, Immune complex assays, Complement assay |
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Term
| Immediate treatment for anaphylaxis |
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Definition
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Term
| Used to treat immune-complex responses |
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Definition
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