Term
|
Definition
| liver cells filled w/ fat/damaged by inflammation, cells die, replaced by fibrotic tissue & nodules (scar tissue) |
|
|
Term
| Cirrhosis contributing factors |
|
Definition
| hepatitis B&C, alcoholism, certain medications, biliary tract obstruction |
|
|
Term
|
Definition
| hepatic blood flow inhibited, portal HTN, decreased serum albumin, increased plasma oncotic pressure, reduced renal blood flow, altered aldosterone production/metabolism, Na retention, ascites, splenomegaly, hyperammonemia |
|
|
Term
|
Definition
| increased serum enzymes, bilirubin,& ammonia, hypoalbuminemia, low platelets & increased prothrombin time, jaundice, itching, ascites, splenomegaly, wt loss, malnutrition, hepatic encephalopathy/coma, liver biopsy: fibrous tissue & nodule formation |
|
|
Term
|
Definition
| dietary protein, sloughed cells, GI bleeding, urea, cellular metabolism |
|
|
Term
| Cirrhosis nutritional mgmt |
|
Definition
| 35-40 kcal/kg, or indirect calorimetry (best), small frequent meals & hs snack, protein: 1.2-1.5 g/kg/d to promote +N balance, protein restriction maybe necessary if HE flares up, no fat restriction unless steatorrhea present, CHO tolerance varies, vit/mineral supplementation, Na restricted to <90mEq |
|
|
Term
|
Definition
| (atomic wt/valence e-)*mEq = mg |
|
|
