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HUN4446 test 2
Cirrhosis
7
Health Care
Undergraduate 4
03/19/2009

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Cards

Term
Cirrhosis
Definition
liver cells filled w/ fat/damaged by inflammation, cells die, replaced by fibrotic tissue & nodules (scar tissue)
Term
Cirrhosis contributing factors
Definition
hepatitis B&C, alcoholism, certain medications, biliary tract obstruction
Term
Effects of scar tissue
Definition
hepatic blood flow inhibited, portal HTN, decreased serum albumin, increased plasma oncotic pressure, reduced renal blood flow, altered aldosterone production/metabolism, Na retention, ascites, splenomegaly, hyperammonemia
Term
Cirrhosis lab results
Definition
increased serum enzymes, bilirubin,& ammonia, hypoalbuminemia, low platelets & increased prothrombin time, jaundice, itching, ascites, splenomegaly, wt loss, malnutrition, hepatic encephalopathy/coma, liver biopsy: fibrous tissue & nodule formation
Term
Sources of blood ammonia
Definition
dietary protein, sloughed cells, GI bleeding, urea, cellular metabolism
Term
Cirrhosis nutritional mgmt
Definition
35-40 kcal/kg, or indirect calorimetry (best), small frequent meals & hs snack, protein: 1.2-1.5 g/kg/d to promote +N balance, protein restriction maybe necessary if HE flares up, no fat restriction unless steatorrhea present, CHO tolerance varies, vit/mineral supplementation, Na restricted to <90mEq
Term
mEq to mg conversion
Definition
(atomic wt/valence e-)*mEq = mg
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