Term
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Definition
| 2 main lobes (essential 4 life), made of hepatocytes, bile canaliculi, & sinusoids |
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Term
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Definition
| portal vein/hepatic artery -> sinusoids -> central hepatic vein -> inferior vena cava |
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Term
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Definition
| blood volume regulation, detoxification, bile production, metabolic functions |
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Term
| Liver metabolic functions (CHO) |
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Definition
| glycogen synthesis & storage, glycogenolysis, monosaccharide conversion, conversion of amino acid residues |
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Term
| Liver metabolic functions (fat) |
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Definition
| formation of lipoproteins, fatty acid oxidation, cholesterol & phospholipid synthesis, bile salt formation, conversion of CHO & protein to fat |
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Term
| Liver metabolic functions (protein) |
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Definition
| deamination of amino acids, synthesis of plasma proteins, syntehsis of prothrombin/clotting factors, urea formation, transamination |
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Term
| Liver metabolic functions (other) |
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Definition
| storage of vitamins/minerals, blood coagulation |
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Term
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Definition
Standard Panel: AST(SGOT), ALT(SGPT), alkaline phosphatase, gamma glutamyl transpeptidase(GGT), albumin, total bilirubin
Other: prothrombin time, serum calcium, serum ammonia |
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Term
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Definition
hepatic duct+cystic duct=common bile duct
common bile duct+pancreatic duct=ampulla -> duodenal papilla & sphincter of Oddi |
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Term
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Definition
| aqueous emulsifying agent that helps in absorption of fatty acids monoglcerides, cholesterol, and lipids by forming micelles |
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Term
| Hypocalcemia contributing factors |
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Definition
| low serum albumin, impaired vit D metabolism, decreased bile salts -> malabsorption of fat & fat-soluble vits -> "soap" formation |
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Term
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Definition
| [(4-acutal serum albumin)0.8]+actual serum calcium = corrected serum calcium (normal range 8.5-10.8mg/dL) |
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Term
| Typical liver disease serum chemistry profile |
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Definition
Increased: ALT, AST, alkaline phosphatase, GGT, ammonia, total bilirubin, prothrombin time
Decreased: albumin, calcium, prothrombin synthesis |
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