Term
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Definition
| chronic IBD that mainly affects the colon and ileum. can damage all layers of colon and attack different sections (skipping). It produces a cobblestoning with thickened wall and fat-wrapping |
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Term
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Definition
| diarrhea, abdominal pain and tenderness, weight loss, anorexia, fever, perianal fistula, increased inflammatory markers: ESR & C-reactive protein |
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Term
| Crohn's Diagnosis procedures |
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Definition
Symptoms, family history, physical,
Tests: endo/colonoscopy, small bowel xray and barium enema, ct scan, biopsy, ASCA |
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Term
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Definition
| obstruction/perforation of SI, anemia, fistula, abscess, increased risk of colorectal cancer, malnutrition |
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Term
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Definition
| 5-ASA, antibiotics, steroids, steroid sparing anti-inflammatory, biological, antidiarrheal |
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Term
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Definition
mesalmine, sulfasalazine
reduce/control inflammation |
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Term
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Definition
metronidazole, ciprofloxacin
change environment (bacteria) |
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Term
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Definition
prednisone
immunosuppressant |
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Term
| steroid sparing anti-inflammatory |
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Definition
azithioprine, methotrexate, 6-mercaptan
block immune reaction |
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Term
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Definition
monoclonal anitbodies: infiximab, adalimumab
blocks effects of TNF-alpha |
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Term
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Definition
cholestyramine
reduce/control diarrhea |
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Term
| Crohn's nutritional management |
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Definition
| promote wt. maintenance/gain, restrict fat, oxalate, and lactose, correct nutritional, vitamin, and mineral deficiencies |
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