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Human Physiology
Physiology Power Point 2 Organic Chemistry
66
Physiology
Undergraduate 2
03/15/2013

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Term
Biomolecule fuel sources
Definition

Carbohydrates

Fats

Proteins

Term
two common features of biomolecules
Definition

Carbon backbone

Presence of C, H, O

Term
Biomolecules =
Definition
organic molecules associated with living organisms
Term
COOH
Definition
Carboxly Acid
Term
OH
Definition
Hydroxyl
Term
NH2
Definition
Amino
Term
H2PO4
Definition
Dihydrogen Phosphate
Term
Monosaccharide, disaccharide, and polysaccharide are examples of?
Definition
Carbohydrates
Term
Monosaccharide and Disaccharide are examples of
Definition
Simple Sugars
Term
Example of complex carbohydrate
Definition
Polysaccharide
Term
Fructose and glucose are?
Definition
Monosaccharide
Term
Sucrose and lactose are?
Definition
Dissacharide
Term
Glucose + Fructose =
Definition
Sucrose
Term
Glucose + Glucose =
Definition
Maltose (disaccharide)
Term
Galactose + Glucose =
Definition
Lactose (disaccharide)
Term
Starch is?
Definition
A polysaccharide from plants
Term
Glycogen is?
Definition
Polysaccharide from animals (produced in liver and muscles)
Term
Long branching chain of simple sugar, specifically glucose?
Definition
Polysaccharide
Term
4 categories of Lipids?
Definition

Fatty acids

Phospholipids

Steroids

Eicosanoids

Term
Lipid that is solid at room temp
Definition
Fat
Term
Lipid that is liquid at room temp
Definition
Oil
Term
Lipid = fat =
Definition
triglyceride
Term
Waste product of tryglyceride is
Definition
Ketoacid
Term
A fat that has all single bonds and solid at room temp
Definition
Saturated fat
Term
A fat with one double bond and is liquid at room temp
Definition
Unstaurated fat
Term
A fat with more than one double bond and is liquid at room temp
Definition
Polyunsaturated fat
Term
Properties of trans fat
Definition

not found in nature

are carconogenic (cancer causing)

denatured polyunsaturated fat

Term
cis-bond
Definition
same side
Term
trans-bond
Definition
opposite side
Term
Fatty acids with trans-bonds are
Definition
carcinogenic
Term
Amphipathic
Definition
Is an element that is both polar and nonpolar
Term
Nonpolar bonds are?
Definition
Hydrophobic, they do not dissolve in water
Term
Properties of Phospholipid
Definition

has two fatty acids chains at the nonpolar end

are modified triglycerides

are amphipatic

found only in human cell membranes as bilayer

Hydrophobic tails

hydrophilic heads

Term
Decreases cell permeability to small water soluble molecules
Definition
Cholesterol
Term
Denovo Sythesis
Definition
The synthesis of complex molecules from simple molecules.
Term
Properties of proteins
Definition

compose 10 - 30% of cell mass

some are structural - bones, hair

some are functional - antibodies, enzymes

Term
Proteins are made up of ..... amino acids
Definition
20 different amino acids
Term
All amino acids contain
Definition

Amine group

Carboxcylic acid

Functional group

Term
There are .... essential and .... non-essential Amino Acids
Definition

9 essential

11 non-essential

Term
Amino acids are bonded together by?
Definition
peptide bonds
Term
A polypeptide is a ?
Definition
protein
Term
50 or more amino acids are called a protein or
Definition
polypeptide
Term
Most proteins contain ... amino acids
Definition
1,500 - 50,000 amino acids
Term
4 Forms of proteins
Definition

Primary - long flat sructure

Secondary - an alpha helix, or Beta pleated sheet

Tertiary - glob

Quatenary structure - 4 globs together (Hemoglobin)

Term
Denatured protein
Definition
is a protein that has lost it's function, either by changing shape too many times, or rise in temp
Term
Fibrous protiens
Definition

secondary structure

strand like proteins

structural proteins - collagen

Term
Globular proteins
Definition

compact spherical proteins

have tertiary and quaternary structures

are functional proteins - antibodies, hormones, enzymes, membrane transporters, DNA regulatory proteins

Term
A stable protein
Definition
Fibrous protein
Term
Unstable protein
Definition
Globular
Term
In order for a protein to change it's shape it needs?
Definition
PO4 (phosphate)
Term
Ribose + Adenine
Definition
Adenosine
Term
Adenosine + PO4
Definition
AMP - Adenosine monophosphate
Term
AMP + PO4
Definition
(ADP) Adenosine diphosphate
Term
ADP + PO4
Definition
(ATP) Adenosine triphosphate
Term
Catabolism is also known as?
Definition

ATP production

Adenosine triphosphate Production

Term
An enzyme is a ?
Definition
globular protein that acts as a catalysts
Term
Ligand?
Definition
ligand is a molecule that binds to another molecule
Term
A substrate is a ligand that bonds to ?
Definition
an enzyme
Term
What can speed up or slow down reactions
Definition
an enzyme
Term
Enzyme high specificity
Definition
allows only one type of chemical to come into the active site
Term
Enzyme low specificity
Definition
allows several different types of chemicals to come into the active site
Term
3 basic steps for enzyme mechanism
Definition

enzyme binds with a substrate at the active site

enzyme substrate complex is rearranged to form a product

the enzyme releases the product then goes back to it's original shape

Term
cofactor
Definition
an enzyme helper such as copper, iron, and vitamins
Term
An enzyme ends in ?
Definition

"ase"

Kinase

Phosphatase

Peptidase

Dehydrogenase

Term
Affinity
Definition
The degree to which a protein is attracted to a ligand
Term
Enzyme activity deponds on
Definition

Proteolytic activation

Cofactors and coenzymes

Temperature

pH

competitive inhibitors

Allosteric modulators

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