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Human Physiology
Exam #3 Gastrointestinal Tract Organ
30
Biology
Undergraduate 2
11/16/2011

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Term
What is the functions of the Mouth, Teeth, Salivary Glands, Pharynx, and Esophagus?
Definition

Mastication saliva secretion

Degluttition (Swallowing Center)

Upper and lower esophageal sphincter action

Term
What are the functions of the stomach?
Definition

HCl acid secretion (parietal cells, in body)

Pepsinogen secretion (cheif cells, in body)

Mucus secretion (polysccharides)

Hormone gastrin secretion (antrum)

Term
What are the functions of the duodenum?
Definition

Absorption of end-products of digestion

Peristalsis and Segmentation

Mucus secretion

Disaccharidase enzyme production

Term
Sucrose is broken down by 1.                              into 2.                                       .
Definition

1. Sucrase

2. Glucose + fructose

Term
Lactose is broken down by 1.                               into 2.                                    .
Definition

1. Lactase

2. Glucose + Galactose

Term
What is maltose broken down by and what is it broken into?
Definition

1. Maltase

2. glucose + glucose

Term
What is the functions of the Large Intestine?
Definition

Reabsorption of 3 L water per hour from digestive juices

Mass Movements

Bacterial incubator (vit K source)

Term
What are the functions of the pancreas?
Definition

Secreation of pancreatic juice (via ducts)

Digestive enzyme synthesis and secretion

Secretion of bicarbonate ion

Secresion of hormone insulin (islets of Langerhans) into blood

Secretion of hormone glucagon (islets) into blood

Term
Amylases break down...
Definition
starch into maltose
Term
Proteases break down...
Definition
proteins to amino acids
Term
Nucleases break down...
Definition
 DNA & RNA to nucleotides
Term
Lipases break down...
Definition
thryglycerides to glycerol + 3 fatty acids
Term
What are the functions of the liver?
Definition

Synthesizes and secretes bile salts (fr. parenchymal cells); recycles via enter-hepatic circulation. Bile salts are detergents derived from cholic acid

Excretes bile pigments, extracting into bile canaliculi the out via bile ducts

Stores glucose as glycogen; released glucose into blood

Center for gluconeogenesis (amino acids & glycerol converted to glucose

Detoxifies and/or inactivates drugs, chemicals, steroid hormones & metabolies

Synthesizes plasma proteins: clotting factors, carrier proteins, complement system proteins and albumin

Active site for reticuloendothelial cells

Liver parenchymal cells can regenerate

Term
What is the function of Gall Bladder?
Definition
Receives some of the bile collected from liver, reabsorbs water and concentrates bile salts. Contracts after a fatty meal to increase detergent level in gut to emulsify fats
Term
Know the picture on page 46
Definition
Term
What is the definition of the hormone?
Definition
A chemical signal which is secreted into the blood, binds to a protein receptor on or in a target cell to cause a change in the target-cell's function
Term
Hormones may be made from 1.                    , 2.                       , 3.                           , or 4.                           .
Definition

1. Peptides

2. Proteins

3. Steroids

4. Amines

Term
A peptide is composed of...
Definition
Less than 100 aa, like insulin and all of the digestive enzymes listed below
Term
Proteins are...
Definition
more than 100 aa, like LH
Term
Steroids are..
Definition
Cholesterol based molecules, like aldosterone, estrogen, testosterone, and vitamin D
Term
Amines are...
Definition
Modified amino acids, like thyroid hormone and epinephrine
Term
Where is Gastrin secreted?
Definition
G-cells in the atrum of the stomach
Term
What tissue does gastrin act on?
Definition
Parietal cells of the stomach, stomach smooth muscle
Term
What are the effect or effects that gastrin has?
Definition
Stimulated the secretion of HCl; growth of new parietal cells in the stomach
Term
What is the stimulus for the secretion of gastrin?
Definition
High protein or amino acids in the stomach; vagus nerve stimulation
Term
What does CCK-PZ stand for?
Definition
Cholecystokinin-pancreaozymin
Term
Where is CCK-PZ secreted?
Definition
Duodenum (also found abundantly in the brain)
Term
What tissue does CCK-PZ act on?
Definition

Pacrease (exocrine)

Gall bladder

Smooth muscle

Term
What effects does CCK-PZ have?
Definition
Stimulates the secretion of pancreatic enzymes (including lipases & proteases.
Stimulates gall bladder contraction -> released conc. bile salts
Term
What is the stimulus for the secretion of CCK-PZ?
Definition
High fatty acids, high AA, or partially digested protein in chyme of duodenum
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