Term
| How do Nucleoside/tide Reverse Transcriptase Inhibitors (NRTIs) work |
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Definition
Bind to catalytic site of reverse transcriptase and interfere with HIV viral RNA-dependent DNA polymerase, resulting in inhibition of viral replication |
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Term
| Black box warning for NRTIs |
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Definition
Lactic acidosis
Toxicities: peripheral neuropathy
pancreatitis
lipatrophy
myopathy
anemia |
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Term
| How are NRTIs mainly eliminated |
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Definition
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Term
|
Definition
Stavudine
Lamivudine
Abacavir
Tenofovir
Emtricitabine
Didanosine
Zidovudine
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Term
|
Definition
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Term
| Brand name for Abacavir + lamivudine |
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Definition
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Term
| What must one be screened for prior to abacavir therapy |
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Definition
MUST screen for HLA-B 5701 allele - if positive, increased risk for hypersensitivity reaction (resulting in death)
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Term
| Black box warning for Abacavir |
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Definition
Serious, possibly fatal hypersensitivity
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Term
| How should didanosine be taken |
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Definition
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Term
| Brand name for didanosine |
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Definition
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Term
| Black box warning for didanosine |
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Definition
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Term
| Avoid the combo of didanosine and ? |
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Definition
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Term
| is peripheral neuropathy a high risk for this medication |
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Definition
| yes (20%); eye exam q 6-12 months |
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Term
| Brand name for Emtricitabine |
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Definition
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Term
| Brand name for Emtricitabine + tenofovir |
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Definition
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Term
| Brand name for Emtricitabine + tenofovir + efavirenz |
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Definition
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Term
| When and how should Atripla be taken |
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Definition
| on an empty stomach preferably at bedtime |
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Term
| Brand name for lamivudine |
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Definition
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Term
| Brand name for lamivudine + abacavir |
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Definition
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Term
| Brand name for Lamivudine + abacavir + zidovudine |
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Definition
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Term
| Black box warning for epivir |
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Definition
do not use epivir-HBV for treatment of HIV
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Term
|
Definition
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Term
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Definition
| Statement. Not a question. |
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