Term
| The liver is a tissue active in cholesterol synth, what does it produce? |
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| The intestine are involved in cholesterol synthesis, what do they make? |
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| The adrenal cortex is involved in cholesterol synthesis, what does it make? |
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| The reproductive organs are involved in cholesterol synthesis, what do they make? |
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Definition
| reproductive sex steroids |
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Term
| name the carbon source and the energy source for cholesterol synthesis. |
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Definition
| All the carbons are from acetyl CoA |
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Term
the reaction for the rate-determining step in cholesterol biosynthesis and give the name of the enzyme which catalyzes this reaction.
This is the rxn HMG-CoA --> to form mevalonate |
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| In the synthesis of cholesterol there is a portion of the process that starts with Acetyl CoA and later to HMG CoA and later to mevalonic acid and it ends with ? These are condensation rxns |
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Term
| HMG CoA is fdeedback inhibited by ? |
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| HMG CoA is stimulated by ? (dephosphorylated enzyme) |
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| HMG CoA is inhibited by ? (phosphorylated enzyme) |
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| What hormone stimulates HMG CoA via induced enzyme synthesis? |
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| What enzyme that contributes to reverse transport of cholesterol also called plasma lipid transfer protein, is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. It collects triglycerides from very-low-density (VLDL) or low-density lipoproteins (LDL) and exchanges them for cholesteryl esters from high-density lipoproteins (HDL), and vice versa. Most of the time, however, it does a homoexchange, trading a triglyceride for a triglyceride or a cholesteryl ester for a cholesteryl ester. |
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Definition
| CTEP (Cholesteryl ester transfer protein ) |
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Term
| What enzyme that is involved in reverse transport of cholesterol is an enzyme that converts free cholesterol into cholesteryl ester (a more hydrophobic form of cholesterol), which is then sequestered into the core of a lipoprotein particle, eventually making the newly synthesized HDL spherical and forcing the reaction to become unidirectional since the particles are removed from the surface. The enzyme is bound to high-density lipoproteins (HDLs) and low-density lipoproteins in the blood plasma. |
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Definition
| Lecithin-cholesterol acyltransferase (LCAT, also called phosphatidylcholine-sterol O-acyltransferase) |
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| In reverse transport of cholesterol what helps convert HDL 3 to HDL 2? |
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| Primary bile acids are made in the ?, they contain how many hydroxyl groups? |
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Secondary Bile Acids: Derived from ? ? ?, made in intestine by micro-organisms
They have how many hydroxyls? |
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| name an important function of bile salts. |
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| Used in the emulsifation of dietary fat |
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| What are the major end products of cholesterol degradation, these things are also re-used |
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First bile salts are reabsorbed by ? ?
Second bile salts are reabsorbed by ? ? |
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Definition
active transport
passive process |
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