Shared Flashcard Set

Details

HSCI 345 Final
New Material
367
Health Care
Undergraduate 3
12/04/2008

Additional Health Care Flashcards

 


 

Cards

Term

Ethics is accountability to whom?

 

Definition

The public

Workers

Professional communities

Funders

The environment

Yourself

Term

Foundation of Public Health ethics

 

Definition
"First do no harm"
Term
AIHA Code of Ethics
Definition

1. Recognize that the health, lives, and wellbeing of other people depends on your professional judgement.

2. Counsel affected paties factually regarding their health

3. Keep confidentiality

4.  avoid circumstances where your interests might be conflicted

5. perform services only in the area of your competence

 6. act responsibly to uphold the integrity of your profession

Term
Environmental Justice
Definition
Making low income, minority communities as safe as others.
Term
Toxic chemical release ratio of colored people to white people
Definition

2.13

 

higher risk of being affected for colored people

Term
Ratio of exposure to facilities emitting hazardous pollutants, coloreds to whites
Definition
2.8
Term
Ratio of cancer risk from air pollutants (coloreds to whites)
Definition
1.72
Term
Hispanics are ___% more likely to die in the construction industry than other people
Definition
50%
Term
Occupational disadvantages for minority, low income, and undocumented workers
Definition

1. have limited legal, financial, educational, and health resources

2. have lower overall health status

3. may be subject to high stress levels

4. Ununionized, more vulnerable to firing

 5. Tend to get the most dirty and dangerous jobs

Term
____ is a specialty field of medicine concerned with maintaing and improving the health of workers.
Definition
Occupational medicine
Term
Incidence of work related injuries and illnesses
Definition

Injuries: 4.9 million ... 5,542 deaths

 

Illnesses: 334,000 ... 47,000 deaths

Term
Top 3 industries with most fatal injuries
Definition
Agriculture, mining, construction
Term
4 most common occupational diseases
Definition
musculoskeletal, pulmonary, dermatologic, infection
Term
6 types of musculoskeletal disease
Definition
neurologic, tendonitis, strain, sprain, arthritis, mechanical lower back pain
Term
5 types of pulmonary occupational disease
Definition

1. airways (occ. asthma, reactive airways dysfunction syndrome)

2. pneumoconioses (asbestosis, silicosis, cwp)

3. cancer (bronchogenic carcinoma, mesothelioma)

4. infection (tb, histoplasmosis, psittacosis)

5. hypersensitivity pneumonitis (farmer's lung, pigeon breeder's lung, malt worker's lung)

 

Term
___ is the most common occupational lung disease
Definition
occupational asthma
Term
___ syndrome follows high levels of irritant exposure
Definition
reactive airways dysfunction syndrome
Term
arsenic, asbestos, chloromethyl ether, chromium, nickel, polyaromatic hydrocarbons, radon, and tobacco smoke are all risk factors for ___.
Definition
bronchogenic carcinoma
Term
___ is a risk factor for mesothelioma
Definition
asbestos
Term
4 types of dermatologic diseases
Definition

1. contact (irritant and allergic)

2. acne

3. pigmentation disorders

4. skin cancer

Term
Irritant dermatitis is caused by?
Definition
Anything that can irritate skin: organic solvents, cleaning products, fuels, etc.
Term
___ dermatitis, has a delayed hypersensitivity
Definition
delayed
Term
4 methods of infection
Definition

Airborne

Bloodborne

Contact

Droplet

 

 

ABCD

Term
___ is an airborne infectious agent with a diameter of 5-10 microns.
Definition
TB
Term
____ virus is a droplet infectious agent with a diameter of 100 microns that quickly fall and get trapped in the upper airways.
Definition
Respiratory synctial virus
Term
MRSA is a ___ infectious agent.
Definition
Contact
Term
3 bloodborne pathogens
Definition
HIV, Hep B, Hep C
Term
3 Preventative measures for occupational diseases
Definition
Administrative, engineering, PPE
Term
Human health concerns related to water (methods of exposure)
Definition

1. contaminated drinking water

2. swimming in poluted water

3. falling out of a boat into polluted water

4. eating contaminated fish

Term
Potential diseases associated with contaminated water exposure
Definition

1. gastroenteritis

2.  ear, eye, nose, and throat infections

3. hepatitis

4. cholera

5. leptospirosis

Term
Presence of pathogens in water is indicated by monitoring for ____.
Definition
E. Coli
Term
Most ___ are not harmful, but their presence in water indicates that harmful viruses, bacteria, or protozoa may also be in the water. Indicates contamination by ____.
Definition
E. Coli, fecal matter
Term
Water quality standard for safe swimming is ____  for a single sample or ____  for a geometric mean
Definition
235 CFU E. Coli/100mL water, 126 CFU E. Coli/100mL water
Term
The department of _____ monitors for E. Coli levels in water.
Definition
Indiana Department of Environmental Management
Term
The ____ act was passed in 1972. It forms the basis for water quality regulation in the US today.
Definition
Clean Water Act
Term
Goal of the Clean Water Act
Definition
waters of the US should be "fishable and swimmable"
Term
Water quality standards are set by which government? (state or federal)
Definition
state
Term
3 components of water quality standards
Definition

- designated uses

- criteria

- antidegradation

Term
CFU
Definition
Colony forming units
Term
___ are numbers that are used to determine whether water meets its designated use (for example 126cfu/100ml water)
Definition
criteria
Term
Point Sources of water pollution
Definition

- comes out of a pipe (sewage treatment plants, industry)

 

Term
What sources of water pollution are regulated by the clean water act? (point/nonpoint)
Definition
point sources
Term
Non-Point sources of water pollution
Definition

- exact location is not easily identified

- not regulated

- ex: agricultural runoff

 

Term
___ sources of water pollution are considered the greatest concern to water impairment. (point, nonpoint)
Definition
non-point
Term
Non-point pollution most often occurs when?
Definition
When it rains - often called "wet weather pollution" or "polluted runoff"
Term
Common nonpoint sources of pollution
Definition
sediment, pathogens, nutrients, pesticides
Term
___ and ___ are common contaminants of fish
Definition
Mercury and PCB's
Term
___ is the most common form of organic mercury found in the environment and is the form that accumulates in both fish and humans.
Definition
Methylmercury
Term
87% of mercury emissions is from ___ and ___.
Definition
solid waste incineration, and fossil fuel combustion
Term
Health effects of methylmercury
Definition

CNS effects

developmental toxin

Term
Natural sources of PCB's
Definition
none
Term
Health effects of PCB's
Definition

- liver

- gastrointestinal 

- blood

- skin

- endocrine

- immune

- CNS

- reproductive

 - developmental 

Term
___ can cause developmental effects, liver cancer, and skin rashes in humans
Definition
PCB's
Term
EPA has classified PCB's as Group b2 carcinogen, which means:
Definition
probable human carcinogen
Term
Where do we obtain water in Indiana?
Definition

40% from surface water

60% from ground water

Term
Water is usually disinfected with ___ in public water systems.
Definition
Chlorine
Term
How is water treated in the US before being considered safe to drink?
Definition

- coagulation

- filtration

- disinfection

- taste/odor reduction

- fluoride added

Term
___ Act regulates public drinking water systems
Definition
US Safe Drinking Water Act
Term
US Safe Drinking Water Act doesn't regulate ___.
Definition
Private wells
Term

Safe Drinking Water Act requirements

 

Definition

- sets max contaminant levels and MCLs for over 100 chemicals and contaminants

- tests water regularly

- notify customers of what was found in water

 

Term
___ is a major concern (contaminant) where surface water is used.
Definition
Atrazine
Term
PPCPs
Definition

Pharmaceuticals and Personal Care Products

- can contaminate water

Term
___ refer to a wide range of anthropogenic or naturally occurring compounds that elicit estrogenic responses by mimicking endogenous estradiol
Definition
Environmental Estrogen
Term
Evidence of environmental impacts of water contaminants
Definition
Mutations in animals (esp frogs)
Term
Ground water contaminants
Definition

- Nitrate

- Pesticides

- Volatile organic chemicals (gasoline, solvents, etc)

- Microbiological Contaminants (bacteria, viruses, etc)

- Road Salt

Term
Nitrate concerns
Definition

- linked to hypoxia in the Gulf of Mexico

- Blue baby syndrome in drinking water

 

Term
Nitrate drinking water standard
Definition
10 ppm
Term
About __-__% of private wells exceed the Nitrate standards
Definition
3-5%
Term

Nitrogen leaching from:

1. septic systems

2. corn fields

Definition

1. 25 lbs/system

2. 20-40 lbs/acre

Term
___ of Indiana's population is not connected to a sewer system... which can lead to contaminating ground water.
Definition
1/3
Term
___ is a naturally occurring element in rocks and soils that can contaminate ground water.
Definition
arsenic
Term
Health effects of arsenic
Definition
skin, bladder, and other cancers
Term
Arsenic drinking water standard
Definition
10 ppb
Term
___ links geographic location with info
Definition
Geospatial technologies (GIS)
Term
___ is biological in nature (capable of self replication) and has the capacity to produce deleterious effects upon other biological organisms, particularly humans.
Definition
Biological hazard
Term
Biological hazard agents
Definition

- infectious (bacteral, viral) or parasitic

- non-infection microorganisms such as fungi, yeast, algae

- plants and plant products

- animals and animal products

Term
3 Key Elements for disease
Definition
host, agent, environment
Term
Bubonic plague - host, agent, environment, results
Definition

Host: rat and flea

Agent: bacteria (yersinia pestis)

Environment: close quarters, poor hygiene conditions allowing for proliferation of rats

 

Results: 75 million deaths

1/3 of Europe's and 1/2 of China's populations died

60% fatality rate

Term
___ was histories deadliest pandemic
Definition
Spanish Flu of 1918
Term
Spanish Flu of 1918: virus, mortality rate, infection rate, deaths, results
Definition

virus: H1N1

2-20% mortality rate

50% infection rate

50-100 million deaths in 1 year

 

victims died by drowning in their own lung fluid

Term
___ in 1993 resulted in 1 Navajo death in AZ. Was isolated from the deer mouse. Results?
Definition
Hantavirus: HPS (Hantavirus Pulmonary Syndrome)
Term

___ is a bacterial infectious disease that infects 1/3 of the world's population. Health care workers are most at risk

Definition
TB
Term
___ is a disease caused by soil contaminated by bird and bat droppings and spread by aerosolized dust. Is Endemic in midwest (95%)
Definition
Histoplasmosis (H. capsulatum, fungus)
Term
___ is a disease that infects livestock producers, meatpackers, and vets that presents with flu-like symptoms
Definition
Brucellosis (Brucella bacteria)
Term
___ is a disease caused by ticks, domestic cattle, sheep, and goats (direct contact or inhalated of dried tissue), presents with flu-like symptoms.
Definition
Q Fever (rickettsial, bacteria-like organism)
Term
___ is caused by bacteria from goal and wool hair, is spread through blood (septicemia).
Definition
Anthrax
Term
___ is caused by inhalation of fungal spores and causes an allergic, asthmatic response. most often in farmers and grain mill workers.
Definition
Aspargillosis (fungus)
Term

Any worker exposed to contaminated organic dust and has flu-like symptoms might have ____.

 

Definition

Organic Dust Toxic Syndrome (ODTS)

 

may be bacterial or fungal

Term
Avian Flu: virus, transmission, mortality rate, deaths, current phase.
Definition

virus: H5N1

transmission: only human to human

mortality rate: >50%

Estimated 5-150 million deaths

Phase 3 of 6 phase system

Term
If the avian flu hits humans, it is estimated that __% of the workforce will be out.
Definition
30
Term
____ is a mold found in a variety of cheeses and antibiotics.
Definition
Penicillium
Term
Toxic components of Penicillium
Definition
endotoxins (bacteria), mycotoxins (fungi)
Term
___ are in the cell wall of gram-negative bacteria, is a complex polysaccharide/protein/lipid mix, and is released upon the death of an organism.
Definition
endotoxins
Term

___ are in spores released from fungi and are a metabolic by-product.

 

Definition
mycotoxins
Term
___ is known as "black mold".
Definition
stachybotrys
Term
Requirements for Indoor and Outdoor fungi
Definition

- Written plan

- Determination of primary/secondary exposure potentials

- annual training in universal precautions and sharps

- HBV vaccination offered at no cost to worker

Term
Other controls for Biological agents
Definition

- biohazard sign

- safety cabinets

- disinfection

- ppe

Term
Potential animal biological hazards
Definition

- dander, saliva, feces, and urine

- cockroaches

- animal bites, stings, scratches

- dust mites

Term
Main health effect of animal hazards
Definition
asthma, 36-75% of asthmatic children are allergic to cockroaches
Term

Animal allergens:

cockroach, dust mites, cats

Definition

Cockroaches: Bla g 1

Dust mites: Der p 1, Der f 1

Cats: Fel D1

Term
____ is an environmental agent that acts by transmitting force or energy to humans.
Definition
Physical agent
Term
Problems with Noise
Definition

- hearing loss

- disrupts sleep/learning

- may add to high blood pressure and stress

- increases job safety risks

 

Term

# of noise exposed workers in US

 

Definition
30 million
Term
# of current workers who will develop noise-induced hearing loss by age 60
Definition
5 million
Term
Range of human hearing, frequency and sound intensity.
Definition

Frequency: 50 Hz - 20kHz

Intensity: 10E-22 W/m^2 - 100W/m^2 (0-140 dB)

Term
___ is hearing loss caused by damage to the inner ear. It affects hearing sensitivity particularly at certain sound frequencies. Is caused by noise exposure and aging, and may be accompanied by tinnitus.
Definition
Sensorineural hearing
Term

Tinnitus

 

Definition
ringing in the ears
Term
___ are a weighted average level for noise of combined frequencies which take into account the fact that some frequencies are more damaging than others.
Definition
dBA (decibels)
Term
OSHA, ACGIH and NIOSH, and community noise limits
Definition

OSHA - 90dBA

ACGIH, NIOSH - 85 dBA

Community: 70 dBA

Term
Physiological range of core temp... when does death occur?
Definition
at 75 degrees F or 110 degrees F
Term

Heat ___ is characterized by lethargy, cold clammy skin, and weakness.

Heat ___ is much more serious and is characterized by weakness, severe headache, dizziness, confusion, hot dry skin, no sweating, and shutdown of body's thermal regulation.

Definition
exhaustion, stroke
Term
There are approx __ work-related heat deaths/year.
Definition
40
Term
Safety issues associated with heat stress
Definition

- Lack of alertness

- lack of balance, motor skills

- fainting

- sweat (slipping, electrical hazard)

 

Term
Risk factors for heat injury
Definition
age, obesity, genetic predisposition, illness, protective clothing, lack of acclimatization
Term
Preventative measures for occupational heat injury
Definition

Worker screening and acclimatizaiton

Scheduling breaks

Fluid replacement

Surveillance

Engineering controls

Education

Term
___ is electromagnetic radiation whose quantum energy is too low to ionize atoms.
Definition
non-ionizing radiation
Term
Nonionizing radiation examples
Definition

electric and magnetic fields

radiofrequency

microwave radiation

infrared, visible, and ultraviolet light

 

Term
Adverse affects of NonIonizing radiation
Definition

tissue heating

electrical interactions

breaking chemical bonds

Term
Nonionizing radiation is from ___ to ___ on the electromagnetic spectrum
Definition
10E3 to 10E-7 m (wavelength)
Term
Frequency calculation
Definition

F=c/wavelength

 

c=3E8 m/s

Term
Quantum energy equation
Definition

Eq = hf

 

h = 4.12E-15 ev-sec

Term
Effects of powerlines and cancer
Definition
Epidemiological studies have found small increases in childhood cancer associated with power lines, but there is no convincing evidence.
Term
Health affects of radiofrequency and microwave radiation
Definition
tissue heating, fetal damage, cataracts, sterility, behavioral affects
Term
TLV for radiofrequency/microwave radiation
Definition
1 mw/cm^2 at 100 MHz
Term
Results of cell phone use and cancer studies
Definition
no apparent correlation
Term
UV radiation can cause
Definition

skin cancer/aging

cataracts

Term
OSHA regulations for PPE
Definition

- complete hazard assessment (survey, written report)

- selection of appropriate safety equipment

- provide training for use of PPE

Term
1st century respirators
Definition
Animal bladders (pliny)
Term
Early respirators
Definition

1st century - animal bladders

1825 - smoke filters

1850 - smoke cap

Term
SCBA
Definition
Self-contained breathing apparatus
Term
Potential for toxicity and exposure concepts
Definition

- speed of reaction

- severity

- irreversibility 

Term
Loose fitting RPE must be ___ pressure
Definition
positive
Term
___ respirators clean the contaminants fromt he air breathed
Definition
Air Purifying respirators
Term
___ respirators have particulate removal mechanisms
Definition
particulate air purifying respirators
Term
HEPA
Definition

High efficiency particulate air

 

remove 99.97% of particulate matter

Term
____ respirators have specific materials for specific chemicals. Remove chemicals by aDsorption.
Definition
gas/vapor air purifying respirators
Term
A physical surface phenomenon that uses special materials with greatly enhanced surface area to attract harmful molecules to surface by Van der Waals forces
Definition
Adsorption
Term

Adsorbent impregnated with contaminant-selective substances.

 

example?

 

Definition

Chemisorption

 

ex: activated charcoal treated with iodine for Hg removal

Term

An internal phenomenon where the contaminant penetrates.

 

example?

Definition

Absorption

 

NaOH or KOH wiht lime or caustic silicates for acid gas collection

Term

Influencing a chemical reaction w/o involvement in it

 

example?

Definition

Catalysis

 

hopcalite (Mn and CuO granules) converts CO to CO2

Term

A ____ is small enough to be conveniently mounted on a respirator facepiece.

 

For concentrations up to __%

Definition

cartridge

0.1%

Term

A ___ is a chin-mounted facepiece or belt-mounted and connected to facepiece with hose.

 

For concentrations up to ___%.

 

Used for?

Definition

Canister

2%

IDLH escape

Term
When removal capacity of a respirator has been exceeded and the chemical begins to pass through.
Definition
Breakthrough
Term
___ respirators combine particulate, gas, and vapor protection, and use a canister and cartridge
Definition
multi-function air purifying respirator
Term
___ respirators are the only positive pressure air purifying respirator and are good for workers with breathing problems.
Definition
PAPR - powered air purifying respirator
Term
___ provide air from a clean independent source, and can be used for higher concentrations of toxins.
Definition
atomsphere supplying respirators
Term
___ atmosphere supplying respirators maintain a constant positive pressure in mask
Definition
continuous flow
Term
___ atmosphere supplying respirators shut off during exhalation
Definition
demand
Term
___ atmosphere supplying respirators provide a small, constant flow that maintains a positive pressure in the mask at all times.
Definition
pressure-demand
Term
___ respirators are atmosphere supplying respirators that provide clean air from a portable external source
Definition
SCBA
Term
Return to Card List
Definition
Term
3 Administrative measures for occupational safety
Definition

Education

Avoidance

Screening

Term
4 methods of engineering a safer work environment
Definition

- substitute safer materials

- revise process

- barriers to minimize exposure

- isolation rooms

Term
4 types of work in occupational medicine
Definition

clinical

research

education

administration

Term
An employer has the right to know what about an injured/sick worker
Definition

- details of exposure

- diagnosis

- restrictions on patient's ability to work

 

cannot know: info not related to worker's comp or fitness for duty

Term
syndrome defined as the development of respiratory symptoms shortly after a single accidental inhalation of high concentrations of an irritant. Symptoms followed by asthma-like symptoms and airway hyperreactivity for a prolonged time.
Definition
Reactive Airways dysfunction syndrome
Term
4 major concepts of industrial hygeine
Definition
AREC - anticipation, recognition, evaluation, control
Term
A ____ is a representation or determination of an airborne contaminant or physical phenomenon. is an estimate of the total substance.
Definition
sample
Term

___ is a determination of the reproducibility of a sample.

___ is a comparison to the "true value" of a sample.

Definition
precision, accuracy
Term
Random vs. systematic errors
Definition

random = indeterminate

systematic = determinate, biased

Term
What could be the sources of error in an industrial hygeine study?
Definition
sampling error, analytical method, sampling environment
Term
A sample is a good estimate of the exposure of interest if it is ____.
Definition
representative
Term
5 reasons to sample
Definition

recordkeeping

evaluating engineering controls

comply with standards

assess exposure of workers

identify contaminants

Term
4 places where samples can be taken
Definition

personal

environmental

biological

medical

Term
Know Action Levels
Definition
Term

active vs. passive sampling

 

Definition

active: with a pump, a generated airflow

passive: no pump, ambient environment

Term
Instantaneous vs. integrated sampling
Definition

Instantaneous: grab or continuous, peaks

Integrated: average

Term
Direct vs. Indirect sampling
Definition

Direct: detect-analyze in one or series of steps

Indirect: two steps - collect for later analysis

Term

What sampling technique?

Direct: aerosol photometry, condensation nuclei, beta attenuation, electric charge

Indirect: filters, impacters, impingers, cyclones

Definition
Particulate
Term

What method of sampling?

Direct: colorimetric, gas chromatography, spectrophotometry

Indirect: Adsorption, absorption

Definition
Gases/Vapors
Term
PJ
Definition
Professional judgement
Term
_____ are based on very limited data and professional judgment.
Definition
Bayesian statistics
Term
LOD
Definition
Limit of Detection - involved in sampling something too soon
Term
___ is the logical step after recognition and evaluation, used to eliminate/correct the problem.
Definition
Control
Term
NIOSH control model
Definition
Technical (engineering, control monitoring) and People (PPE, work practices) aspects
Term
3 methods of engineering control
Definition

Substitution

Isolation

Ventilation

Term
Classic IH approach control model
Definition

Engineering controls

administration

ppe

Term
3 methods of substitution
Definition

material - use a less toxic chemical

equipment

process

Term

What would be an appropriate (less toxic) substitute for each of these materials?

carbon tetrachloride

benzene

solvent based inks

Definition

percholoethylene

toluene

water based inks

Term
6 methods of administrative control
Definition

scheduling

location

housekeeping

hygeine

maintenance

training/education

Term
___ is a method of controlling the movement of air
Definition
ventilation
Term
5 purposes of ventilation
Definition

regulate temp and humidity

material recovery and control

 prevent fire and explosions

satisfy OSHA requirements

prevent health hazards

Term

2 types of ventilation

 

Definition

GEV: general dilution of ventilation

LEV: Local exhaust ventilation

Term
Components of an LEV system
Definition
hoods, ducts, air cleaners, fans
Term
What chemical, although banned from production in the US since 1979 still shows up in our waters, sediments, fish and people?
Definition
PCBs
Term
Universal precautions
Definition
assume any substance is dangerous
Term
True or false: the OSHA bloodborne pathogen standard applies only to health workers.
Definition
false
Term
Type of hearing loss generally associated with noise exposure
Definition
sensorineural
Term
Unit of noise exposure that takes into account the fact that not all frequencies of noise are equally damaging to the hearing system
Definition
dBA
Term
4 categories of respiratory fit testing
Definition

User seal checks (fit checks)

Qualitative fit tests (QLFT)

Quantitative fit tests (QNFT)

Term
____ checks (resp fit test) are performed prior to fit testing and before each use.
Definition
User seal checks
Term
2 types of user seal check
Definition

negative pressure

-seal off facepiece inlet valves 

- inhale and hold breath

- facepeive remaining slightly collapsed means good fit

 

positive pressure

- seal off exhalation valve

- exhale

- facepiece slightly expanding indicates good fit

Term
Fit test exercises (perform each for 1 min)
Definition

Normal breathing (NB)

Deep breathing (DB)

Move head side to side (SS)

Move head up and down (UD)

Talking (T)

Term

Irritant smoke test, bitrex solution test, isoamyl acetate test, saccharin solution test

 

are all part of  the ____ test

Definition
QLFT
Term

generated aerosol chamber tests, controlled negative chamber tests, and ambient aerosol test

 

are all part of ____ tests.

Definition
QNFT
Term
___ are an identifiable means of estimating or determining how much protection a respirator will afford its wearer.
Definition
Fit Factors/Protection Factors
Term
The ___ factor accounts for uncertainty in determining respirator protection.
Definition
safety factor
Term
___ are QNFT results obtained during normal work activities
Definition
Workplace protection factor
Term
The ____ factor is the ratio of concentration outside mask to concentration inside mask
Definition
fit factor
Term
Father of industrial hygiene.
Definition
ramazzini
Term
mother of industrial hygiene
Definition
alice hamilton
Term
father of toxicology
Definition
Paracelsus
Term
First occupational epidemiologist
Definition
sir percival pott
Term
The concept that for many chemicals, there is an amount small enough to not cause significant harm to the majority of those exposed on a daily basis.
Definition
Threshold/ NOEL or NOAEL
Term
2 famous US factory fires and the year in which they happened
Definition

Triangle shirtwaist (1911)

NC chicken plant (1991)

Term
In mixtures, the presence of one toxic material increases the toxic action of the other
Definition
synergism
Term
In mixtures, the presence of a nontoxic material increases the toxic action of a toxic material.
Definition
Potentiation
Term
In mixtures, the toxic action of two materials is the summed effect of each given alone.
Definition
Addition
Term
In mixtures, the existence of one material reduces or interferes with the toxic action of another material
Definition
Antagonism
Term
What was the disease that struck down many workers who were digging the Hawks Nest Tunnel at Gauley Mountain in th 1930's?
Definition
Silicosis
Term
Name one of the 2 "defining"smog incidents that occurred in the mid 1900's that created a sudden awareness of the public health implications of air pollution
Definition
Donora Fog, London Fog
Term
What incident in the 1980's in India suddenly connected industrial chemical activities with environmental health implications due to a disastrous chemical relase that killed thousands of people in the surrounding community?
Definition
Bhopal
Term
A toxicant typically goes through four steps in its path through the body, reperesented by the acronym ADME, what does that stand for?
Definition

Absorption

Distribution

Metabolism

Excretion

Term
The art and science of industrial hygiene porblem solving can be summed up wiht the following four words that make up AREC.
Definition

Anticipation

Recognition

Evaluation

Control

Term

____ means to develop symptoms more readily than the average population.

 

____ means an allergic response.

Definition

Hypersusceptibility

Hypersensitivity

Term
3 major routes of entry that allow chemicals into the body
Definition

inhalation

ingestion

percutaneous

Term
4 types of aerosol particulate matter than can become airborne from different industrial processes
Definition
fumes, dust, smoke, mist
Term
____ is the dose at which 50% of those who take in a toxin die from it
Definition
LD50
Term
Rare liver cancer caused by exposure to vinyl chloride in rubber factories
Definition
angiosarcoma
Term
The common name of a disease that often resultd in facial disfurement and necrosis of the jaw bone in workers molding poste for matches.
Definition
Phossy Jaw
Term
Exposure to a chlorinated solvent such as trichloroethylene in conjunction with drinking alcohol can result in reddening of the face and neck known as ____.
Definition
Degreaser's flush
Term
concentration from which a worker must be able to escape without losing her life or suffereing permanent health damage.
Definition
IDLH
Term
An airborne concentration value which best represents a worker's composite exposure over a certain period of time such as an 8 hr day.
Definition
TWA
Term
The EPA's term for exposure limits for newly developed chemicals
Definition
NCEL
Term
An airborne concentration level which is set and enforced by the US OSHA or a state OSHA program
Definition
PEL
Term
A recommended airborne concentration level which is established by the ACGIH
Definition
TLV
Term
If a chemical has a particularly acute biological response, a 15 minute averaging tem period is used to establish a recommendd or required airborne concnetration level, called ____
Definition
STEL
Term
A level of chemical in a body fluid or other material as a result of biological monitoring which is likely to be ovserveed in healthy workers exposed to a chemical by any route of entry
Definition
BEEL
Term
EPA's 6 ambient air criteria pollutant standards from the Clean Air Act are the ____.
Definition
NAAQS
Term
a level of chemical in a body fluid or other material as a result of biological monitoring which is likely to be ovserved in healthy workers exposed to an airborne level of the chemical at it's TLV is known as the ____.
Definition
BEI
Term
One of the guidelines developed by the AIHA for chemicals that are felt to require more study and /or info than is currently available
Definition
WEEL
Term
Another guideline developed by the AIHA which is gaining worldwide recognition for general population exposures in emergency situations such as a spill
Definition
ERPG
Term
the air concentration at which certain regulatory requirements such as personal sampling and medical surveillance become required is known as the ____?
Definition
AL
Term
Chemical Y has a TLV-TWA=3mg/m^3 with a STEL+12mg/m^3. What would be the total time during an 8 hour work day that a worker could be expossed to a constant concentration level of 12 mgm^3 and still meet all the requirements for the TLV guidelines?
Definition
5x the STEL = 60 min
Term
Workers in a pesticide plant in California in the 70's were working with a chemical known as dibromochloropropane (DBCP) which the workers themselves discovered caused?
Definition
sterility
Term
The term "gasoline fume" is often used, but it is actually "gasoline ____"
Definition
vapor
Term
a submicron particle formed by condensation fo a vaporized material
Definition
fume
Term
When a pregnant woman is exposed to an agent that adversely effects the developing fertilized egg, the agent is called a ____.
Definition
teratogen
Term
when exposure takes place in the organogenesis stage of a pregnancy and an adverse reaction results, the toxin is known as ____.
Definition
an embryotoxin
Term
The first act of federal legislation that significantly addressed safety and health issues in the workplace and was the forerunner of the OSHAct was the ____.
Definition
Walsh-Healy Act
Term
In comparison to occupational exposure limits, the exposure limits for the non-occupational community are often higher/lower/the same.
Definition
lower
Term
The tissue/organ with the highest activity for metabolism of foreign chemicals is?
Definition
liver
Term
A ____ acts by interfering with the trasnport of oxygen by the blood to the tissues.
Definition
chemical asphyxiant
Term
The proportion or percentage of a population that has a particular disease or other health related characteristic is?
Definition
prevalence
Term
incidence or prevalence of disase refers to:
Definition
morbidity
Term
In the souce-medium-receptor model of environmental hazards, kids at risk for childhood lead poisoning are considered the _____.
Definition
receptor
Term

The odeds ration in an epidemiological study provides an estimate of the:

 

relative risk

chance of exposure

change of disease

severity of disease

Definition
relative risk
Term
An epidemioogy study that compares people wiht disease to normal individuals is called a ____ study.
Definition
case-control
Term
Which type of epidemiological study is always retrospective?
Definition
case control
Term
Which type of epidemiological study compares health outcomes between people living in one location wtih those living in a different location?
Definition
ecologic
Term

___ refers to the need for a healthy environment for all people regardless of race or income level.

Definition
environmental justice
Term
____ refers to collecting health event data in a population
Definition
public health surveillance
Term
The standard mortality ratio is computed as
Definition
observed dealths divided by expected deaths
Term
Odds ratio calculation
Definition
(exposed cases/exposed controls)/(unexposed cases/unexposed controls)
Term
a p-value less than 0.01 indicates that?
Definition
it is unlikely that the results of the study could have occurred by chance
Term
when a worker cannot detet the presence of a chemical because it has overpowered his sense of smell, we say that he is suffering from _____.
Definition
Term
In biological monitoring, a finding of reduced sperm motility would be considered a biomarker of ____.
Definition
effect
Term

a reason that most occupational health professionals prefer the TLV over the PEL is:

generally there ism ore documentation on the scientific basis for TLV's

TLV's tend to be more stringent 

TLV's are updated more frequently

TLV's are based only on health, not politics

Definition
all of the above
Term

toxicalogically, the most important dose of a toxic airborne chemical agent is:

- the concentration times the exposure time (Haberer's Law)

- the amount of the material retained by the lung tissue and not exhaled

- the amount of material absorbed into the blood from what is retained in lung tissue

- the amount transported to the target organ of concern by the blood

Definition
the amount transported to the targe organ of concern by the blood
Term
The "skin" notation for asubstance in the TLV indicates what?
Definition
that the substance can be absorbed through the skin
Term
Author of famous mining text De Re Metallica, that was the "state of the art" on mining operations
Definition
Bauer/ Agricola
Term
the chemical involved in the Bhopal chemical disaster
Definition
methyl isocyanate
Term
family of cellular, test tube, petri dish type tests
Definition
in vitro
Term
the family of tests using live animals
Definition
in vivo
Term
the name of the toxicological model developed to provide an integrated comparative evaluation of various systems and characteristics between two species that are being studied
Definition
PBPK
Term

Arrange the following exposure limits in order

a. PEL-peak

b. PEL-TWA

c. PEL-STEL

d. IDLH

e. PEL-ceiling

Definition
d, a, e, c, b
Term
The ____ is sometimes used as an alternative to FEV1 in measuring airflow obstruction.
Definition
peak flow test
Term
The PO2 of arterial blood is a measure of?
Definition
the amount of O2 dissolved in the blood.
Term
two major types of lung disease
Definition
restrictive and obstructive
Term
compared to mucociliary clearance, phagocytosis acts more slowly/rapidly
Definition
slowly
Term
______ have played key roles in air pollution disasters bc they concentrate pollutants close to the ground.
Definition
temperature inversions
Term
in relation to ozone exposure children are considered more vulnerable because?
Definition
they have smaller airways and tend to spend more time outdoors
Term
calculate aerodynamic diameter when given diameter and density
Definition
AD = sqrt(density)x(diameter)
Term
____ in the atmosphere primarily comes from the interaction of other air pollutants with sunlight.
Definition
ozone
Term
a characteristic of ____ that is different from many irritants is the immunological response to a specific agent.
Definition
allergens
Term
factors thought to enhance the toxicity of PM2.5
Definition

large surface area

ability to penetrate the lung

chemical composition

Term
the ____ is a useful device in air sampling because it is used to obtain a sample of respirable particulate
Definition
cyclone
Term
An approximate range for the size of nanoparticles is ____.
Definition
<100nm
Term
lung condition caused by an allergic reaction in the alveolar region of the lung
Definition
hypersensitivity pneumonitis
Term
What type of disease is a major concern for PM2.5 exposure?
Definition
heart
Term

Mesothelioma refers to cancer where?
What is it caused by?

 

Definition

pleural lining of lung

 

asbestos

Term
People wiht obstructive lung disease usually show decreased ____.
Definition
FEV1
Term
People with restrictive lung disease usually show decreased ____.
Definition
lung volume
Term

___ lung disease is characterized by less lung area.

____ lung disease is characterized by making it harder to breathe air in.

Definition
restrictie, obstructive
Term
two particles with equal ____ will tend to have equal lung penetration
Definition
aerodynamic diameter
Term
A property of ____ that distinguish them from other particles is that their length is at least three times their diameter or width.
Definition
fibers
Term
a toxic substance found in cotton dust that causes lung prbolems
Definition
endotoxin
Term
____is most associated with the scarring of lung tissue and space occupying lesions?
Definition
fibrosis
Term
a property of ozone that makes it more damaging to the alveolar region of the lung than sulfur dioxide is its:
Definition
low solubility
Term
People may be exposed to thimerol, an organomercury compound because?
Definition
it is used in vaccine formulations
Term

a property of amphibole asbestos fibers is that they:

1.are relatively straight compared to serpentine fibers

2. are relatively nontoxic compared to other forms

3. include chrysotile and crocidolite

4. are easily dissolved in body fluids

5. include amosite and cristobalite

Definition
1
Term
the gauley bridge disaster involved many worker deaths due to what disease?
Definition
acute silicosis
Term
EPA's designation of Hazardous Air Pollutants refers to
Definition
200 substances which may cause cancer, birth defects, or other health efects
Term
Criteria air pollutants
Definition
ozone, particulate matter, CO, NO2, SO2, lead
Term
a solvent associated with causing blindness in humans
Definition
methanol
Term

An OSHA officer has the right to immediately shut down an operation if he/she determines it to be an imminent danger.

 

true or false?

Definition
false
Term

OSHA has the right to ban a chemical that is considered to be too dangerous to use in industry.

 

true/false

Definition
false
Term

Minimata Bay incident

 

what chemical?

what effects?

 

Definition

mercury

neurological

Term
___ was released into the Jinzu River in Japan and caused Itai-Itai disease
Definition
manganese
Term
Benzene causes ____.
Definition
leukemia
Term
Manganese is widely used in welding, steel production, batter production, and as a fuel additive. It is known to cause symptoms similar to _____ disease.
Definition
Parkinsons
Term
If there is no existing OSHA standard, but it can be established that a commonly recognized hazard exists, an OSHA compliance officer can still cite an employer under the _____ clause.
Definition
general duty
Term
excess exposure to funmes from metals created during weldnig can cause flu-like symptoms, this illness is known as:
Definition
metal fume fever
Term
most toxic valence state of chromium
Definition
hexavalent: 6
Term
most toxic valence of arsenic?
Definition
3: trivalent
Term
OSHA programs in which management and labor organizations cooperate with OSHA in meeting minimum helath and safety rules.
Definition
voluntary protection program
Term
major health effect of cellosolves
Definition
reproductive
Term
European Union initiative that deals with the responsible managment of toxic materials
Definition
REACH
Term
Aerodynamic diameter that best characterizes a repirable aerosol
Definition
<4um
Term
PEL and TLV for asbestos
Definition
0.1 f/cc
Term
lung damage that occurs with exposure to silica
Definition

progressive massive fibrosis

 

progressive and nodular

Term
most toxic form of mercury
Definition
methyl mercury
Term
____ is the medical procedure used for evaluating pneumoconiosis
Definition
xrays
Term
Erin Brockovich chemical
Definition
chromium
Term
OSHA's levels of citations that can be used when an inspector observes a violation in the workplace
Definition
serious, non-serious, willful (knowing), failure to abate, repeat, de minimus
Term
For mixtures, the Hazard Communication Standard requires that hazard info be supplied on the MSDS for any component greater than ___% if considered a hazardous material, and ___% if consdiered a carcinogen.
Definition
1, 0.1
Term
3 characteristics of a confined space
Definition

not menat for continuous occupancy

limited entry/exit

large enough for a person to enter

Term
If a confined space is found to contain a hazardous atmosphere, then it is referred to as a ____ confined space.
Definition
permit-required
Term
3 job functions that must be done when someone enters a confined space
Definition

entrant, entry supervisor, attendant

 

only 2 people needed

Term
3 major forms of free crystalline silica
Definition

cristobalite

quartz

trydomite

Term
3 major forms of asbestos
Definition

chrisotile

amosite

crocidolite

Term
3 forms of amorphous (non-crystalline) silica
Definition
diatomaceous earth, silica gel, silica fume
Term
Regulatory act initially adopted in 1977 that mong other things, established the NAAQS and National Emission Standards for Hazardous Air Pollutants (NESHAPS)
Definition
Clean air act
Term
regulator act initially adopted in 1976 which requires manufactureres to perform toxicity testing and then file a premanufacturing notification (PMN) at least 90 days prior to the release of a new chemical into the market
Definition
toxic substances control act
Term
regulatory act initially adopted in 1976 which requires the responsibility of properly managing hazardous chemicals from "the cradle to the grave" including issues dealing with treatment, storage and disposal of chemical wastes, as well as to encourage waste minimization and recycling
Definition
Resource conservation and recovery act
Term
regulatory act initially adopted in 1980 which created a mechanism to deal with uncontrolled and abandoned hazardous waste sites, including handling emergencies, cleaning up the sites, and charging the responsible parties... created a new agency, ATSDR
Definition

comprehensive environmental response, compensation, and liability act

 

CERCLA

Term
regulatory act that created authority for indoor air quality activities required OSHA to establish a hazardous waste operations and emergency response regulation for workers and created authority int eh area of community Right to know
Definition

Superfun amendment and reautherization act

 

SARA

Term
Federal agency charged with enforcing regulation agencies (CERCLA, SARA, etc)
Definition
EPA
Term
supreme court decision that resulted in an OSHA officer being required, if asked by a company owner, to seek a serach warant and limit his/her inspection to only that
Definition
Barlow's decision
Term
4 key requirements of the Haz Com standard that must be provided to or made available to workers
Definition
MSDS, training, written program, labeling
Term
the lowest temp at which a liquid gives off enough vapor to form an ignitable mixture in the presence of an ignition source
Definition
flash point
Term
method used under medical supervision to reduce lead levels in the body by chemically reacting the lead with other chemicals which can then be excreted.
Definition
chelation
Term
temp at which combustion will be initiation and self-sustained without a source of ignition
Definition
autoignition temp
Term
form of hemoglobin that cannot carry O2 to the cells, created by nitroaromatic hydrocarbons
Definition
methemoglobin
Term

Given: LEL, UEL, MW, Density, Fl.Pt., TLV, max concentration

 

find VP

Definition
VP/760 x 10^6 = max concentration
Term

Given: LEL, UEL, MW, Density, Fl.Pt., TLV, max concentration

 

find VP at flash point

Definition
VP/760 x 10^6 = LEL x 10^5
Term

Given: LEL, UEL, MW, Density, Fl.Pt., TLV, max concentration

 

find VHR

Definition
VHR = max conc/TLV
Term

____ liquids have a flash point < 100 degrees F

____ liquids have a flash point > 100 degrees F

Definition
flammable, combustible
Term
airborne limits for the OSHA lead standard
Definition
50 ug/m^3
Term
biological limits for lead for removal from work and return to work
Definition

removal: >60ug/L

return: <60ug/L

Term

"medical removal protection" standard for OSHA lead standard

 

how long does the standard provide protection? 

what worker's rights are protected?

Definition
18 mos, salary and position
Term
OSHA regulated chemical (other than lead) has standards for biological monitoring in addition to air concentrations
Definition
cadmium
Term

ketones are usually just irritants and flammable, but there are two, more dangerous toxic exceptions. what are they?

 

what do they have in common?

resulting health effect?

Definition

n-hexane

methyl n-butyl ketone

 

they are toxic metabolites

 

peripheral neuropathy

Term
3 major different types of classic health effects attributed to organic solvnets
Definition

CNS

Lung

Skin

Term
dark line across gums is a sign of ___ exposure
Definition
lead
Term
metal that causes metal fume fever
Definition
zinc
Term
worker has metal sliver in his hand and the would does not seem to health, what metal?
Definition
beryllium
Term
metal associated with siderosis
Definition
iron
Term
garlic breath is a sign of overexposure to?
Definition
selenium
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