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HPA 310 Cancer
Dr. Dansky, HPA 310, Fall 2011, PSU
61
Health Care
Undergraduate 3
12/04/2011

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Cards

Term
Different causes of cancer
4
Definition
-Genetic
-Viral
-Chamical
-Radiation
Term
Genetic cancers
examples
Definition
-Chronic Myelocitic cancer (CML)
-Breast Cancer
Term
Viral cancer
examples
Definition
-cervical cancer (HPV)
-liver cancer (Hepatitis)
Term
Chemical cancer
examples
Definition
-Lung cancer (smoking)
-head/neck,esophageal, (asbestos)
Term
Radiation cancers
examples
Definition
-skin cancer
-Leukemia, lymphoma, thyroid cancer
Term
Lifetime risk
definition
Definition
probability over a lifetime that an individual will get cancer
Term
Lifetime risk
men, lung cancer
Definition
1 in 13 men will get lung cancer
Term
Relative risk
definition
Definition
measure the relationship between a risk factor and a particular cancer
Term
Male smokers
relative risk
Definition
Male smokers have 20x relative risk of lung cancer
Term
women and breast cancer
relative risk
Definition
women with 1st degree relative wih breast cancer hav 2x relative risk of developing breast cancer
Term
Cancer Stage
definition
Definition
how far the cancer is advanced
Term
How staging is determined
Definition
-extent or spread of disease from site of origin
-TNM
Term
In situ
definition and example
Definition
-finding abnormal cells
-using a pap smear, cervical cancer ONLY in situ currently available
Term
Invasive
definition and example
Definition
-cancer cells spread beyond the original layer
-any cancer NOT detected using a pap
Term
TNM staging
acromyn breakdown
Definition
-Tumor size
-Node involvement (presence/absence of regional lymph node involvement
-Metastases progression/absence
Term
Why staging is important
Definition
essential in determining choice of therapy and assessing prognosis
Term
Stage 0
definition and example
Definition
-in situ
-only cancer currently being detected this way is cervical
Term
Stage 4
definition
Definition
-most severe prognosis
-worst survival rate
Term
5-year survival rate
definition
Definition
% of people still alive 5 years after dianosis (considers secondary illnesses, outlying conditions)
-patients may be disease free, in remission, or undergoing treatment
Term
Male-specific cancers
Definition
-testicular
-Prostate
Term
Female-specific cancers
Definition
-Breast
-Ovarian
-Cervical
Term
Men cancer rates (new cases per 100,000)
Definition
-prostate - 156
-lung - 75.2
-colon - 55
Term
Women cancer rates (new cases per 100,000)
Definition
-breast - 124
-lung - 52.3
-colon - 41
Term
Treatments
Primary/adjunctive
examples
Definition
-surgey - removal
-chemo - used with radiation
-radiation-localized (good for Stage 1)
Term
Treatments
palliative
examples
Definition
-disease has advanced too far
-not curable
-pain management, focuses on comfort
Term
Breast cancer
facts
Definition
-more common in women, but men are susceptible
-most frequently diagnosed cancer for women
Term
Breast cancer
risk
Definition
-genetics (BRCA 1/2)
-increased estrogen
-early onset menses,
-obesity,
-hormone replacement therapy
Term
Breast cancer
diagnosis
Definition
-early detection through mammogram
-breast self-examination
Term
Breast cancer
Sx
Definition
lump
nipple retraction/discharge
dimpling of skin
pain
Term
Prostate cancer
facts
Definition
leading cause of new cases of cancer in men
Term
Prostate cancer
risks
Definition
-all men
-higher in African-American men
-Age- if you live longer, you'll get it
-genetics
Term
Prostate cancer
diagnosis
Definition
-digital rectal exam
-PSA - prostate specific antiget
Term
PSA
controversy
Definition
-has many false positives
-all men over 50 should have annual PSA
-false elevation b/c BPH, smoking, etc.
Term
Prostate cancer
Sx
Definition
-usually none in early stages
-blood in urine
-obstruction to urinary flow
Term
Prostate cancer
treatment
Definition
-surgery
-radiation
Term
Lung cancer
fact
Definition
-leading cause of cance death overall
-cases in men are decreasing
-cases in women are increasing
Term
Lung cancer
risks
Definition
-smoking
-radon, asbestos, radiation
Term
Lung cancer
diagnosis
Definition
-chest x-ray
-bronchoscopy
-sputum cytology
Term
Lung cancer
Sx
Definition
-persistent cough
-Sputum streaked with blood
-chest pain
Term
Lung cancer
Treatment
Definition
-surgery-pneumonectomy
-radiation
-chemotherapy
Term
Colon cancer
facts
Definition
-3rd leading cause of cancer deaths
Term
Colon cancer
risks
Definition
-over 50
-family history
-pre-existing colon disease (ulcerative colitis)
-colon polyps
Term
Colon cancer
diagnosis
Definition
-stool test for occult (hidden) blood
-colonoscopy
Term
Colon cancer
symptoms
Definition
-blood in stool
-change in bowel habit
-weight loss
Term
Colon cancer
treatments
Definition
-surgery (curative or palliative)
-chemotherapy
Term
Cervical cancer
-cause
-diagnosis
-symptoms
-treatment
Definition
-HPV
-Pap smear
-abnormal vaginal bleeding
-surgery
Term
Ovarian cancer
risks
Definition
women over 50
Term
Ovarian cancer
Symptoms
Definition
-abdominal/pelvic pain
-abnorml vaginal bleeding
Term
Ovarian cancer
treatment
Definition
-surgery/chemo
-poor prognosis
Term
Testicular cancer
risk
Definition
men 18-35
Term
Testicular cancer
symptoms
Definition
lumps
Term
Testicular cancer
diagnosis
Definition
-self-exam
-routine physical
Term
Testicular cancer
treatment
prognosis
Definition
-surgery/chemo
-excellent
Term
Skin cancer
risks
Definition
-caucasion
-sun exposure
-genetics
Term
Skin cancer
non-melamona type
Definition
-squamous cell,basal cell
-skin lesion that does not heal
-sunexposed areas higher risk
Term
Skin cancer
melanoma type
Definition
-mole that changes in size/shape
Term
Diagnosis
ABCD acronym
Definition
-Asymmetry
-Border
-Color
-Diameter
Term
Skin cancer
Treatment - non-melanoma
prognosis
Definition
-surgery
-excellent prognosis
Term
Skin cancer
Treatment - melanoma
prognosis
Definition
-surgery/chemo
-good is lesion is small, non-invasive
Term
Kids leukemia
Definition
ALL-high survival
AML-less common
Term
Adult leukemia
Definition
CLL-high survival
CML-less common
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