Term
| How do entry inhibitors work |
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Definition
Inhibits the fusion of the HIV-1 virus with the CD4 cells by blocking the conformational change in gp41 |
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Term
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Definition
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Term
| Brand name for enfurvitide |
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Definition
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Term
| How is Fuzeon administered |
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Definition
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Term
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Definition
| Statement. Not a question. |
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Term
| How do CCR5 Antagonists work |
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Definition
Binds to the CCR5 receptor on the CD4 cells and prevents the conformational change required for cell entry |
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Term
| Name the CCR5 antagonists |
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Definition
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Term
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Definition
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Term
| What test must be performed prior to starting Maraviroc |
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Definition
Topism test to determine the "tropism" of their HIV since this agent will not work for patients with CXCR4 - tropic disease or in HIV that uses a combo of both coreceptors |
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Term
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Definition
| Statement. Not a question. |
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Term
| How do integrase inhibitors work |
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Definition
inhibits the catalytic activity of HIV-1 inegrase, thus preventing the insertion of HIV DNA into the host genome and virus cannot replicate |
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Term
| Name a inegrase inhibitor |
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Definition
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Term
| Brand name for Reltegravir |
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Definition
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Term
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Definition
| Statement. Not a question. |
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