Shared Flashcard Set

Details

HIV and AIDS
Test 3 Sem 2
13
Medical
Graduate
02/16/2011

Additional Medical Flashcards

 


 

Cards

Term
What defines AIDS?
Definition
HIV antibody positive with CD4 count <200 or CDT4 cells consitute <14% total lymphocytes
Term
What has the highest risk of exposure to HIV? the lowest?
Definition
highest-transfusion of contaminated blood products
lowest-needle stick and sexual transmission
Term
What is the most common route of transmission worldwide?
Definition
sexual contact
Term
What were the majority of occupational exposure to HIV caused by?
Definition
percutaneous exposures
Term
which coreceptors play an important role in the fusion of the virus to the host cell?
Definition
CCR5 and CXCR4
Term
What serves as a strong independent predictor of the progression to AIDS?
Definition
Plasma HIV RNA levels
Term
What serves as a great way to assess the current immunologic status?
Definition
CD4 counts
Term
What is the HIV RNA levels in most acute cases?
Definition
>50,000 copies/ml, most >300,000 copies/ml
Term
CD4 counts greater than what are indicated for good response to vaccines?
Definition
>500/ml
Term
What are the 4 classes of antiretroviral therapy meds?
Definition
1) nucleoside reverse transcriptase inhitors (NRTIs)
2) nonnucleoside transcriptase inhibitors (NNRTI)
3) protease inhibitors
4) fusion inhibitors
Term
What is the recommended HIV tx regimens?
Definition
1) combo of 2 NRTIs plus a protease inhibitor
2) 2 NRTIs plus NNRTI
3) 2 NRTIs plus 2 protease inhibitors
Term
What regimens should be given for occupational exposure prophlaxis?
Definition
1) Xidovudine w/ either lamivudine or emtrictabine
2) Tenofovir with either lamivudine or emtrictabine
Term
when should C-sections be considered with HIV?
Definition
when RNA levels are >1000 at time of delivery
Supporting users have an ad free experience!