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Nucleoside Reverse Transcriptase Inhibitors |
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Zidovudine (Retrovir®, AZT)
Abacavir (Ziagen®)
Tenofovir (Viread®)
Emtricitabine (Emtriva®)
Zalcitabine (Hivid®)
Didanosine (Videx®, ddI)
Stavudine (Zerit®, D4T)
Lamivudine (Epivir®)
MOA: Inhibits reverse transcriptase; incorporates into viral DNA |
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Non-Nucleoside Reverse Transcriptase Inhibitor |
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Etravirine (Intelence®)
Efavirenz (Sustiva®)
Nevirapine (Viramune®)
Delavirdine (Resciptor®)
MOA: Binds to reverse transcriptase and blocks the RNA-dependent and DNA-dependent DNA polymerase activities including HIV-1 replication |
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Saquinavir (Invirase®)
Indinavir (Crixivan®)
Nelfinavir (Viracept®)
Ritonavir (Norvir®)
Amprenavir (Agenerase®)
Lopinavir/Ritonavir (Kaletra®)
Foramprenavir (Lexiva®)
Atazanavir (Reyataz®)
Tipranavir (Aptivus®)
MOA: Binds to the active site of HIV protease and inhibits the activity of this enzyme |
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Maraviroc (Selzentry®)
MOA: Binds to human CCR5 receptors, blocking HIV gp120 attachment and preventing cell entry
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Selzentry®
Entry Inhibitor
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Enfuviritide (Fuzeon®)
MOA: Inhibits fusion of virus with host cell membrane, blocking entry and subsequent viral replication |
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Raltegravir (Isentress®)
MOA: Inhibits HIV integrase, preventing viral DNA insertion into host cell DNA |
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Isentress®
Integrase Inhibitor |
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