Term
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Definition
Amprenavir Atazanavir Fosamprenavir Indinavir Nelfinavir Rotinavir Saquinavir Topranivir Lopinavir/Rotinavir Darunavir |
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Term
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Definition
Bind to active site on protease and prevent cleaving of HIV polyproteins virus remains immature/noninfectious |
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Term
Which is the most effective anti-retroviral |
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Definition
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Term
| Protease inhibitors should be used with |
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Definition
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Term
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Definition
Hyperlipidemia/Hyperglcemia Elevated LFT's Incr bleeding in hemophilia decr bone mineral density Fat metabolism |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| contains propylene glycol (anti-freeze) |
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Term
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Definition
| prolonged PRI and incr bilirubin |
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Term
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Definition
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Term
| Drug interactions of Protease Inhibitors |
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Definition
Ketaconazole Clarithromycin Grapefruit juice Rifampin Phenobarb Phenytoin Carbamazepine St. John Wort/garlic |
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Term
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Definition
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Term
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Definition
| Blocks entry of HIV into CD4 cells |
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Term
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Definition
Diarrhea Injection site rxn (SQ) Nausea/Fatigue Insomnia |
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Term
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Definition
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Term
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Definition
Blocks Chemokine receptor for CCRS-> HIV unable to bind and enter T-cell Must use tropism test for efficacy |
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Term
| What test MUST be performed in order to determine efficacy of Maraviroc |
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Definition
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Term
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Definition
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Term
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Definition
Fever UTI Hepatotoxic CV toxicity malignancy |
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Term
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Definition
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Term
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Definition
| Inhibits integrase -> inhibits viral DNA from incorporating into human DNA |
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Term
| How do you dose Raltegravir |
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Definition
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Term
| Ratlegravir interacts w/ what drug |
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Definition
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