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| Egymption architect, physician, polymath, might have written first surgical texts. |
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| World's oldest medical treatise |
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| Edwin Smith papyrus C. 1600 BC. Discusses diagnosis and treatment of traumatic military injuries. |
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| 1550 BC contains practical advice and magic. There are over 700 drug formulae givem |
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| Most important medical texts in Ancient China |
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The Yellow Emporor's Inner Cannon -Illness has natural causes. -Illness is a disruption of Chi -Human body is a microcosm that reflects the world as a whole, the macrocosm. -Natures 5 phases (wood, fire, earth, metal, water) correspond to parts of the mind/body. |
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| A vital energy that travels through body along "meridians". Disruption of it's flow leads to illness. |
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| Imbalances of yin yang leads to illness according to ancient Chinese. Yin principal is negative, cold, dark, empty, earthly, and feminine. Yang is positive, warm, bright, full, heavenly, and masculine. |
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| Greek contributions to Science |
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-invented purely scientific curiosity -tried to find natural causes -fewer unquestioned assumptions=fewer restraints on imagination. |
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~650-580 BC -first philosopher scientist. Relied on reason rather then experiments -materialist, causal view of nature -Earth is a disc surrounded on all sides by water. -Water is the essence of all things -steam: expanded water, earth: consolidated water. |
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492-432 BC -Materialist and causal view of nature -Originator of the 4 element model of nature: fire, air, water, and earth. These combine because of two forces: love and hate. -unsuccessful combos: malformed monsters -successful combos: humans and animals -Believed we "thought" with our blood. |
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460-360 BC -Peak of Greek philosophy. -ATOMISM -Atoms are infinte in # and shape, neither created or destroyed. -Qualities of matter derive from atom composition -Life and sould are same thing, fire atoms -Breath brings in soul atoms, death, asphyxisa caused by lack of soul atoms |
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| Limitations of first period of Greek natural philosophy |
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-No experimental method -No chemistry beyond atomic/elemental theory -No conception of force/energy beyond attraction/repulsion |
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460-361 BC (~same as Democritis) -Changed early Greek medacine to be more observational and ethical. ("do no harm")("Observe with senses") -Rejected religion,stressed pragmatism and experience. -Study patient rather then disease, gentle treatments |
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| -Hippocratic Collection/Hippocratic Corpus |
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-Collection of works quoting the teachings of Hippocrates. -contained 60-70 works by roughly 19 authors |
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4 fluids of the body -blood, bile, black bile, phlegm -Illness happened in phases; degeneration of humours, coction, CRISIS (evacuation of humours) |
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| Sanguine, choleric, melancholic, phlegmatic |
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| 1858. Replaced humoural pathology with cellular pathology. |
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| Hippocrates view on inheritance |
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-All parts of body produce seed material; traits in offspring arise from mixing male and female seed. -Darwin believed this, called it pangenesis |
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life giving principle in the air which enters the lungs, is taken to the left side of the heart, and distributed by the arteries to the body to sustain it. -Brain is a radiator that cools blood and separates water and mucous. Brain is center of thought and feeling. |
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| The Hippocratic Oath is an oath historically taken by physicians and other healthcare professionals swearing to practice medicine honestly. May not be hippocratic at all and is not historically accurate |
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Aristotle introductory info -Hometown, where he studied.. |
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384-322 BC -Born in Macedonia -father was physician -Studied in Athens at 17 at Plato's Academy for 20 years. -Studied Bio on island of Lesbos. -Fled Lesbos, returned to Macedonia; tutored prince for several years |
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| Hippocrates hometown and travels |
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| -Cos, Asclepiad father. Travelled in Balkans and Asia Minor. |
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| Believed there are no divine beings. Impersonal necessity and natural law govern the world. |
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| Aristotle, Socrates, and Plato ideological shift |
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| Away from purely natural curiosity of the Ionian philosophers, toward more human-centered and theological interests. |
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| Lyceum, in Athens. Est. 334 BC. |
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| died in exile on the island of Chalcis |
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| Natural groups of organisms |
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| Groups whose members have correlated attributes. Some attributes lead to natural groupings, others lead to unnatural groupings. |
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| What attributes tend to lead to natural groups of organisms? |
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-They are essential to organism -They have functional dependence -relatedness/common ancestor |
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| Aristotle's view on anatomy |
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| He thought anatomy should be comparative. Species should be differentiated as their uniqueness was important. |
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| Aristotle's view on physiology |
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-Agreed with Hippocrates -Brain cools the blood and produces mucous. -heart is the organ of soul and intelligence -food is 'cooked' in gut |
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| Who is said to have founded natural history |
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| Aristotle. He was an inspiration to later biologists. |
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| What was wrong with Aristotle's methods? |
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-infected with Plato's essential-ism, no conception of evolution. -not rigorously natural -Natural history could be made to fit Christian theology. |
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| What was the Museum in Alexandria like? |
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| It was a University. "House of Muses" |
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| Who are Herphilus and Erastratus? |
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| (310-260 BC)Physicians and anatomists at Alexandria. Known via secondary sources only. Both probably preformed human dissection (on criminals?) |
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| What was the roman view on physiology and anatomy? (Herphilus and Erastratus) |
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| Blood is synthesized from food and distributed through veins. Pneuma (spirit) is replenished by respiration. Veins and arteries are dead end canals that seeped into organs. |
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| The Roman idea of spirit which is carried by the arteries to the veins. It is then converted into animal spirits which are carried to the muscles, causing movement |
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| What was Erasistratus' view on illness? |
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| Blood left the veins and went into arteries and blocked distribution of pneuma, causing illness. |
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| The shift away from Greek methodology and observation towards phenomology and philosophy. |
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AD 23-79 Historian, encyclopedist. Lawyer, civil administrator, military officer to Roman society. -Wrote 37 volume encyclopedia, Natural History |
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| written by Pliny the Elder. Almost all info culled from ancient authors. Became solid reference work for the next 1500 years. |
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| (1st cent. AD) Wrote large encyclopedia, one portion- De Medicina, survived. Hippocratic, surgeon should assist nature in healing process. Became one of the first medical books to be printed. |
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(AD 130-200) (Height of Roman Empire) -Surgeon to gladiatorial school at Pergamon. -Most prestigious physician in Rome. Mimicked and ridiculed by other physicians. No students or school. |
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Deeply religious, opposed to atomism. -Hippocratic. -Studied anatomy using animals and bones from tombs. |
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| Galen's biological insights |
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-Voice controlled by laryngeal nerves that led to brain, supported idea brain is center of thought and reason. -Arteries contain blood, not air. -Kidney makes urine, not bladder. -Gut peristalsis -Cutting spinal cord at different places led to different results |
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| Galen's beliefs (that turned out to be false) |
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-Blood does not circulate, it moves from liver to tissues. -Venous blood distributes food. -blood enters arterial system through pores connecting r & l ventricles |
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| Galen's therapies for illness |
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-balance humours with diet -balance humours with bloodletting and purging -invasive surgery |
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| Main difference between Greek and Islamic/Arabic Science |
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| Arabic was more experimental. Standardized, hints of control, randomized drug trials. |
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| Reasons science in Islam flourished |
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| Intellectuals were not all religious.Influenced by Greeks. Strength in math, optics, chemistry, medicine. |
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-"a mysterious transformation" -Aims: transmute base metals into gold. Philosophers stone. To find elixirs for health and immortality. Forerunner of Chemistry |
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| Contribution of Alchemy to modern science |
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Chemical techniques & concepts; distillation, glassware (alembic), solutions, acids and bases, transformation, chemical analysis. |
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Abu Sina or Ibn Sina. 980-1037 AD. -Greatest Islamic intellectual. Works became basis of curriculum in European medical schools until mid 17th cent. Physician, mathematician, philosopher, astronomer, physicist. Believed medicine was a science.That cures to illness should be repeatable. |
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| By Avicenna, 14 volume works which incorporated Greek, Roman, and Islamic medicine. Encapsulated Aristotle's concept of purpose in nature, and Galen's anatomy. |
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| 1288. Questioned Galen's blood movement and suggested circulation. First to perform human dissections |
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| Reasons science in Islam passed to Europe in later centuries |
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-No self-sustaining scientific revolution -Printing press allowed for more distribution |
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| The Assimilation of ancient writings into a Christian framework. |
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"Doctor Universalis" (1200-1280) -Literary scholar, alchemist, and teacher. Foremost medieval naturalist. Dsicovered/isolated Arsenic. Open minded about Chemistry. Described new plants, animals, and minerals. -"Aristotle's Ape" |
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| (1225-1274) Pupil of Albertus Magnus. Greatest synthesizer of Science and Ideology in the 13th century. Believed that the Bible plus works by ancient authors provided a complete, self-consistent guide to reality. |
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(1908-1179) Nun, abbess, mystic who wrote religious visions. Healer, naturalist, musician. Sought natural causes of diseases and mental illness. |
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| Frederick 2 of Hohenstaufen |
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| (1194-1250)Student of science and contributor to it. Did not share religion and assumptions of scholastic. Established University of Naples. Chartered Salerno Medical College |
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| Founded by Frederick of Hohenstaufen in 1224. It still exists and is called the University of Napes Fedrico 2. |
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| Chartered by Frederick of Hohenstaufen in 1231. Formal curriculum with standardized exams, produced many medical treatises. Separated the duties of physician from duties of pharmacist. |
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| Universities in Medieval times |
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-Flourished during scholastic period. -Grew from churches -International. Students came from all over Europe. -Most study was in Latin. |
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