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Histology
Hemopoiesis
27
Medical
Professional
06/12/2010

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Term
Name the three processes that constitute the hemopoiesis.
Definition
Erythropoisis, Leukopoiesis, and thrombopoiesis.
Term
When does hemopoiesis happen in the yolk sack?
Definition
First week
Term
In what period do the hepatic and splenic phases of hemopoiesis are operational?
Definition
3rd -7th month
Term
When does the bone marrow phase of hemopoiesis start?
Definition
After 10th birthday
Term
To which places is hemopoiesis confined after the 10th birthday?
Definition
Red Bone marrow9ribs, sternum,pelvis proximal epiphysis of femur and humerus.
Term
How is bone marrow classified?
Definition
Yellow and Red
Term
What characterizes the yellow bone marrow?
Definition
Adipose tissue
Term
What characterizes the red bone marrow?
Definition
Hemopoietic tissue, interspersed adipocytes.
Term
What elements make the bone marrow stroma?
Definition
Reticular cells (currently known as adventitial cells) and the reticular fibres they create.
Term
What are the adventitial cells?
Definition
Relating to the outer coat or adventitia of a blood vessel or other structure.
Term
What is the main difference between stem cells and colony forming units (CFUs)?
Definition
Stem cells produce all the subsets of hemopoietic cells & lack of morphological unique characteristics. CFU’s are capable of producing one particular subset of blood cells
Term
The PPSC gives raise to the
Definition
CFU-L from which lymphocytes develop, and the CFU-GEMM, from which GRANULOCYTIC ERYTHROCYTIC, MONOCYTIC AND MEGAKARYOCITIC CELLS develop.
Term
What characterizes the erythropoietic colonies?
Definition
ROUND NUCLEI,HOMOGENOUS CYTOPLASM
Term
What characterizes the granulocytopoietic colonies?
Definition
NON ROUND NUCLEI
Term
What characterizes the thrombocytopoietic colonies?
Definition
BIG CELLS W/MULTILOBULATED NUCLEI
Term
How many days does erythropoiesis take?
Definition
7
Term
What elements are necessary for a normal erythropoiesis?
Definition
Erythropoitin, vitamins b12,b6,C,E, FLOIC ACID, RIBOFLAVIN,PANTOTHENIC ACID, THIAMIN, IRON, COBALT,MAGANESE AND AMINO ACIDS
Term
Name in order the cells that appear in erythropoiesis.
Definition
P-PROERYTHROBLAST
B-BASOPHILIC ERYTHROBLAST
P-POLYCHROMATIC ERYTHROBLAST
O-ORTOCHROMATIC ERYTHROBLAST
R-RETICULOCYTE
E-ERYTHROCYTE
Term
What erythropoietic cell is characterized by the peak of rRNA content and in which the haemoglobin synthesis starts?
Definition
BASOPHILIC ERYTHROBLAST
Term
What is the earliest erythropoietic cell able to circulate?
Definition
ORTOCHROMATIC ERyTHROBLAST
Term
Name in order the cells that appear in granulocytopoiesis.
Definition
MYELOBLAST>PROMYELOCYTE>MYELOCYTE>BAND>MATURE GRANULOCYTE>MYELOCYTE.
Term
At what stage do the specific granules and hence the differentiation of the basophilic, eosinophilic and neutrophilic colonies starts?
Definition
MYELOCYTE
Term
At what stage does the mitotic phase of granulocytopoiesis ends?
Definition
MYELOCYTE
Term
How many days does granulocytopoiesis take?
Definition
14
Term
Name in order the cells that appear in thrombocytopoesis.
Definition
MEGAKARYOBLASTS,MEGAKARYOCYTES,PLATELETS
Term
What is the highest chromosomic number a megakaryocyte can achieve?
Definition
64
Term
Through what process does the megakaryocyte give raise to platelets?
Definition
MEGAKARYOCYTE CYTOPLASMIC FRAGMENTATION
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