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Histology
Cytology
60
Histology
Professional
09/13/2011

Additional Histology Flashcards

 


 

Cards

Term
Prokaryotic cells
Definition
bacteria; no membrane bound organelles
Term
How many types of cells in the human body?
Definition
200
Term
What does cytoplasm contain?
Definition
organelles, inclusions, matrix
Term
Features of organelles
Definition
living structures, permanent, perform specific functions
Term
Lipid bilayer
Definition
hydrophobic end and hydrophilic end(faces outwards); phospholipids with few cholesterol
Term
Peripheral protiens
Definition
on the outside of the phospholipid bilayer
Term
Integral proteins
Definition
found in the lipid bilayer
Term
Transmembrane protiens
Definition
cross the entire lipid bilayer
Term
Cell coat
Definition
glycocalyx, formed by glycoproteins and glycolipids
Term
Microvilli
Definition
increase surface area; small intestine and proximal convoluted tubule, brush border
Term
Mitochondria
Definition
double membrane organelle, contains DNA, oxidative enzymes, Liver cells (1000 per cell)
Term
What are the main components of the cell?
Definition
Organelles, inclusions, matrix
Term
Mention 3 features of an organoid
Definition
living structures, permanent, and specific function
Term
List membranous organoids
Definition
Cell membrane, mitochondria, rough endoplasmic reticulum, golgi apparatus, lysosomes, smooth endoplasmic reticulum
Term
Which organoid has a double membrane
Definition
mitochondria
Term
List non-membranous organelles
Definition
ribosomes, cytoskeleton
Term
What is the main lipid of the cell membrane?
Definition
phospholipid
Term
What are the types of proteins in the cell membrane?
Definition
integral and peripheral
Term
What do you know about the cell coat and its function?
Definition
made up of glycoprotiens and glycolipids; cell recognition and adhesion
Term
What are the functions of the cell membrane?
Definition
cellular homeostasis, selective permeability, transport of nutrients and oxygen and removal of waste, endocytosis, pinocytosis, phagocytosis, exocytosis, cell membrane receptors, cell coat
Term
What are the types of enzymes inside the mitochondria and their functional significance?
Definition
oxidative enzymes that produce ATP
Term
What is the functional significance of DNA inside of the mitochondria?
Definition
Only organelle that can divide and replicate on its own
Term
Which cells of the body contain large numbers of mitochondria?
Definition
Liver (can be 1000 per cell)
Term
What is the function of Rough Endoplasmic Reticulum?
Definition
Protein synthesis, starts glycosylation and sulphation
Term
Mention a cell that contains abundance of RER and its function
Definition
plasma cell, makes and transports protiens
Term
What are the main components of Golgi apparatus (3)?
Definition
flattened saccules, transfer or microvesicles, secretory vesicles
Term
What are the functions of Goli apparatus?
Definition
Adding sugar, packaging and concentration of secretory proteins, forms lysosomes, recycling reusable membrane proteins
Term
What are the enzymes inside lysosomes?
Definition
hydrolytic
Term
What are the functions of lysosomes during life?
Definition
intracellular digestion, get rid of worn out organelles, release enzymes out of cell
Term
What are the function of lysosomes after death?
Definition
post-mortum autolytic changes
Term
Give examples of cells rich in lysosomes
Definition
neutrophils and marcophages
Term
What are the functions of smooth endoplasmic reticulum?
Definition
steroid hormone synthesis, drug detoxification, glycogen metabolism, calcium release and capture (muscle contraction)
Term
What is the function of attached ribosomes?
Definition
form proteins that are secreted or stored in the cell
Term
What is the function of free ribosomes?
Definition
form proteins that remain in the cell as cytoplasmic functional elements
Term
Name 3 structures that contain microtubules
Definition
centrioles, cilia, flagella, mitotic spindle
Term
What is the structure of a centriole?
Definition
9 sets of triplets of microtubules (27)
Term
What is the structure of a cilium?
Definition
hair-like motile process, 9 sets of duplets with two in the middle of microtubules (20)
Term
What is the structure of a microvillus?
Definition
non-contractile actin microfilaments
Term
What are the different types of microfilaments and their functions?
Definition
Actin (contractile in muscle, non-contractile in microvilli) and myosin (contractile)
Term
List the cytoplasmic inclusions that may be found in the cell
Definition
glycogen, lipids, pigments
Term
What are the four basic components of the nucleus?
Definition
nuclear membrane, nuclear matrix, nucleolus, and chromatin
Term
What is the chemical nature of the nucleolus?
Definition
aggregates of RNA and protein
Term
What are the 3 types of RNA and their role in protein synthesis?
Definition
mRNA (transcription), tRNA (translation), rRNA (ribosomes)
Term
What is the chemical nature of chromatin?
Definition
double strands of DNA forming a double helix
Term
Where is the genetic material of the cell located?
Definition
In the chromatin inside the nucleus
Term
What are the 2 types of chromatin? Which is the biologically active type?
Definition
Heterochromatin and Euchromatin (active)
Term
What is the number of chromosomes in the body cells?
Definition
46
Term
What is the number of chromosomes in ovum/sperm?
Definition
23
Term
What is the clinical significance of karyotyping?
Definition
detects genetic anomalies
Term
What are the main 2 stages of the cell cycle?
Definition
Interphase and mitosis
Term
What do you know about the 3 phases of the interphase?
Definition
G1-cell growth, S - DNA synthesis, G2 - duplication of centrioles
Term
What are the cells that have no cell cycle?
Definition
Nerve cells and cardiac muscle cells
Term
What are the 4 stages of mitosis?
Definition
Prophase, metaphase, anaphase, telophase
Term
What happens during prophase?
Definition
centrioles move to poles, nuclear membrane and nucleolus disappear, coiling of chromosomes
Term
What is the hallmark of metaphase?
Definition
spindle formation with chromosomes lining up
Term
What happens during anaphase?
Definition
seperation of chromatids, migration, circular furrow at equator
Term
What characterizes telophase?
Definition
Splitting into two cells
Term
What is the number of chromosomes in daughter cells after mitosis?
Definition
46
Term
Where does meiosis take place?
Definition
Germ cells
Term
What is the number of chromosomes in daughter cells after meiosis?
Definition
23
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