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Histology
lecture 1
24
Histology
Graduate
08/20/2014

Additional Histology Flashcards

 


 

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Term
BASOPHILIC
Definition
-HEMATOXYLIN
-BLUE
-STAINS ACIDIC STRUCTURES
Term
ACIDOPHILIC/EOSINOPHILIC
Definition
-EOSIN
-PINK
-STAINS BASIC STRUCTURES
Term
PLASMA MEMBRANE FUNCTIONS
Definition
-SELECTIVE BARRIER
-EXOCYTOSIS AND ENDOCYTOSIS
DIFFUSION
SELECTIVE, FACILLITATED AND ACTIVE TRANSPORT
-CELL TO CELL AND CELL TO MATRIX SIGNALLING
- ION CHANNELS
Term
RIBOSOME (STRUCTURE)
Definition
-MADE UP OF rRNA AND 2 PROTEIN UNITS
-BASOPHILIC
-ELECTRON DENSE
Term
MITOCHONDRIA (STRUCTURE)
Definition
-DOUBLE MEMBRANE
-INNER MEMBRANE FOLDS TO FORM CRISTAE
-INTERMEMBRANOUS SPACE
-MATRIX (WITHIN CRISTAE)
Term
MITOCHONDRIA (FUNCTION)
Definition
-ENERGY PRODUCTION
-HEAT PRODUCTION
-PHOSPHORYLATES NUCLEOTIDES
-UNDERGOES FISSION
-APOPTOSIS PARTICIPANT
-PARTICIPATES IN SOME PROTEIN SYNTHESIS
-PROTEINS THAT ARE MADE IN THE CYTOPLASM HAVE A MITOCHONDRIA LOCALIZATION SIGNAL
Term
Protein synthesis (Non- RER)
Definition
-mRNA transcribed in nucleous
-leaves through nuclear pores with poly A tail, and capp
-small ribesomal subunit interacts with start codon of mRNA
-large subunit is called and begins polypeptide chain adding amino acids via the anticodon binding
-stop codon reached polypeptide chian is released
Term
RER Protein Synthesis
Definition
-synthesis occurs similar before reaching the large ribosomal subunit
-once ribosomal complex is formed, it is moved to the ER membrane and binds
-when stop codon is reached the polypeptide chain is released into the cisterna of RER
Term
OUTER MITOCHONDRIAL MEMBRANE
Definition
-Aqueous channels formed by PORIN
-Proteins <5000D can enter
Term
INTERMEMBRANOUS SPACE
Definition
-Contains enzymes that PHOSPHORYLATE NUCLEOTIDES
Term
INNER MITOCHONDRIAL MEMBRANE
Definition
-Have CRISTAE (folds)
-Site of ETC and ATP SYNTHASE
-CARDIOLIPIN (maintains electrochemical gradient because it is impervious to ions)
-THERMOGENIN in BROWN fat (heat) ***
Term
MITOCHONDRIAL MATRIX
Definition
-Contains enzymes for KREBS CYCLE and FATTY ACID OXIDATION
-Some DNA and RNA
-Some PROTEIN SYNTHESIS (ribosome-like structures)
Term
SMOOTH ER (FUNCTION)
Definition
-LIPID METABOLISM
-DETOXIFICATION
-GLUCOSE BREAKDOWN
CALCIUM SEQUESTRATION
-MEMBRANE SYNTHESIS
Term
ROUGH ENDOPLASMIC RETICULUM (STRUCTURE)
Definition
-SMOOTH ER + RIBESOMES
-LINEAR
-CONTINUOUS WITH NUCLEAR ENVELOPE AND SER
Term
SMOOTH ER (STRUCTURE)
Definition
-SINGLE MEMBRANE
-SERIES OF CISTERNAE
Term
CISTERNAE
Definition
-FLATTENED DISKS USUALLY STACKED IN MULTIPLES WHICH COMPRISE OF THE GOLGI APPARATUS
Term
ROUGH ER (FUNCTION)
Definition
-SER FUNCTIONS
-PROTEIN SYNTHESIS
-POST-TRANSLATIONAL MODIFICATIONS
-N-LINKED GLYCOSYLATION
Term
rER PROTEINS
Definition
-Proteins for EXPORT
-Proteins for LYSOSOMES
-Proteins for specific granules in LEUKOCYTES
-MEMBRANE Proteins
Term
RER PROTEINS MANUFACTURED
Definition
-EXPORT
-LYSOSOMAL
-GRANUOLES IN LEUKOCYTES
-MEMBRANE PROTEINS
Term
POST-TRANSLATIONAL MODIFICATIONS OF RER
Definition
-Initial glycosylation of glycoproteins
-Synthesis of phospholipids
-Assembly of multichain proteins
Term
PROTEIN TRANSPORT FROM RER
Definition
-RER
-TRANSPORT VESSICLES FROM RER TO CIS GOLGI
-END AT TRANS GOLGI
-RELEASE OF SECRETORY VESICLES AND LYSOSOMES
Term
PROTEIN SECRETION PATHWAY
Definition
Rough ER -> cis Golgi -> trans Golgi -> vesicle to be secreted
Term
GOLGI APPARATUS (Funtcion)
Definition
-Completes POST-TRANSLATIONAL MODs
-PACKAGES proteins (Essentially the shipping center for proteins from the ER)
-Directs proteins to correct cellular compartments
-O-linked Glycosylation
Term
PROTEIN TRANSPORT FROM RER
Definition
-RER
-TRANSPORT VESSICLES FROM RER TO CIS GOLGI
-END AT TRANS GOLGI
-RELEASE OF SECRETORY VESICLES AND LYSOSOMES
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