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Histology
Integument
70
Histology
Graduate
10/30/2012

Additional Histology Flashcards

 


 

Cards

Term
What are the 3 layers of the skin?
Definition
epidermis, dermis, hypodermis
Term
What are the 5 layer of epithelium in order from deep to superficial?
Definition

1. stratum basale

2. stratum spinosum

3. stratum granulosum

4. stratum lucidum

5. stratum corneum

Term
This layer of epithelium is composed of many layers of flat, dead cells.
Definition
stratum corneum
Term
This layer of epithelium is a translucent squamous layer that lacks organelles.
Definition
stratum lucidum
Term
This layer of epithelium is limited to thick epidermis (footpad, nose, teat).
Definition
stratum lucidum
Term
This layer of epithelium is 1-4 cells thick and composed of flat polygonal cells with basophilic granules.
Definition
stratum granulosum
Term
This layer of epithelium is 2-5 cells thick and is composed of cuboidal to squamous cells.
Definition
stratum spinosum
Term
This layer of the epidermis is attached to the basement membrane by hemidesmosomes.
Definition
stratum basale
Term
This layer of epithelium is composed of 1 layer of cells.
Definition
stratum basale
Term
In the epidermis, stem cells are located in the stratum _________.
Definition
basale
Term
In the stratum ________, mitosis is abundant.
Definition
basale
Term
Cells in the stratum _________ constantly proliferate and can cause cancer.
Definition
basale
Term
The stratum basale is connected to the basement membrane by _____________.
Definition
hemidesmosomes
Term
Brown dots that can be seen in the stratum basale are ___________.
Definition
melanin pigments
Term
__________ is the cell's protection against UV light.
Definition
Melanin
Term
The stratum spinosum is held together by ____________.
Definition
desmosomes
Term
The stratum _________ is connected by desmosomes.
Definition
spinosum
Term
Closer to the basal layer, stratum spinosum cells are more _________ and are more _________ superficially. 
Definition
cuboidal, squamous
Term
The stratum spinosum can be ____ layers in thin skin.
Definition
1-2
Term
The stratum __________ contains keratohyalin granules.
Definition
granulosum
Term
Hair, feathers, and hooves are examples of ______ keratin.
Definition
hard
Term
The corneum is made of _____ keratin.
Definition
soft
Term
The cells in the stratum granulosum make _________ granules.
Definition
keratin
Term
_________ are derived from the neural crest during development.
Definition
Melanocytes
Term
Melanin produced by melanocytes are taken up by _____________.
Definition
keratinocytes
Term

True or False:

You cannot differentiate melanocytes with H&E staining.

Definition
True
Term
Where does melanin accumulate in keratinocytes?
Definition
over the nucleus
Term
____________ contain cytoplasmic extensions.
Definition
Melanocytes
Term
________ increased production of melanin.
Definition
UV rays
Term
___________ cells are derived from monocytes.
Definition
Langerhans/dendritic
Term
Langerhans cells contain _______ granules.
Definition
Birbeck
Term
_________ cells have antibodies at their surface to trap antigens and present them to lymphocytes.
Definition
Langerhans
Term
Langerhans cells are most prominent in the stratum _________.
Definition
spinosum
Term
_________ cells are slow-acting mechanoreceptors for touch.
Definition
Merkel's
Term
Merkel's cells are located within the __________.
Definition
basal layer
Term
_____________ are neuroendocrine cells with dense core granules.
Definition
Merkel's cells
Term

True or False:

Axons that terminate on Merkel's cells are myelinated.

Definition
True
Term
Hair follicles are derived from the _____________.
Definition
epidermis
Term
Hair follicles are located in the _______ layer of the ________.
Definition
reticular, dermis
Term
The four major components of a hair follicle are:
Definition

1. internal root sheath

2. external root sheath

3. dermal pappila

4. hair matrix

Term
Keratinized shingles on hair are known as __________.
Definition
cuticles
Term
The _________ is only found in large hairs and is made of keratinized cuboidal cells.
Definition
medulla
Term
The _____________ is a capillary network around follicles and glands.
Definition
cutaneous plexus
Term
Secondary hair is smaller in diameter and has no _________.
Definition
medulla
Term
Wool is a type of _________ hair.
Definition
secondary
Term
_________ hair is associated with sweat glands, sebaceous glands, and arrector pili.
Definition
Primary
Term
___________ hair is found either in a single or compound follicle
Definition
Primary
Term
____________ hair is shallow and has no sweat glands nor pili muscle.
Definition
Secondary
Term
Whiskers are a type of _________ hair.
Definition
sensory
Term
_________ hairs are associated with some skeletal muscles.
Definition
Sensory
Term
Compound follicles are often fused at the level of the _____________.
Definition
sebaceous gland
Term
A __________ must form before cells in the dermis can send signals to stimulate the proliferation of cells in the epidermis for hair follicle development.
Definition
placode
Term
After a placode is formed, a _____ forms from dermal condensate.
Definition
bud
Term
During the hair cycle, after a hair follicle has been growing, _________ migrate to the bottom of the follicle and begin to form another follicle.
Definition
stem cells
Term
Dogs with short hair have a _______ hair cycle.
Definition
short
Term
Which gene is not functional in long-haired dogs?
Definition
FGF-5
Term
________ signals the hair follicle to stop growing.
Definition
FGF-5
Term
FGF-5 secretion is __________ in aged people.
Definition
increased
Term
Sebaceous glands use which type of secretion mechanism?
Definition
holocrine
Term
________ glands are simple, tubular glands with a coiled secretory portion and a straight duct.
Definition
Apocrine
Term
Sweat glands are _________ glands.
Definition
apocrine
Term
________ glands are found mainly in areas like the nose and footpads.
Definition
Merocrine
Term
Unlike domestic animals, most of the primates' bodies contain _______________.
Definition
merocrine sweat glands
Term
What are the layers of the dermis from deep to superficial?
Definition

1. reticular dermis

2. papillary dermis

Term
The __________ is made of connective tissue that supports the epidermis.
Definition
papillary dermis
Term
The papillary layer is made of _____ collagen from reticular cells.
Definition
Type III
Term
The reticular dermis is made of _____ collagen and elastic fibers.
Definition
Type I
Term
___________ is smooth muscle near hair follicles.
Definition
Arrector pili
Term
_____________ function as pressure receptors.
Definition
Lamellar/Pacinian corpuscles
Term
Loss of __________ in the hypodermis causes loose and sagging skin.
Definition
white fat cells and elastin fibers
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