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Histology Exam 2
Lectures 13-21 and Questions
181
Other
Not Applicable
06/17/2008

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Term
endocrine system
Definition
- consists of glands that produces hormones to regulate growth, development, and metabolic activities of cells
Term
receptors
Definition
cells must have ____ for hormones in order to respond to them
Term
endocrine glands
Definition
- have no ducts
Term
-stomach
- small intestine
- lungs
Definition
cells that are part of the diffuse endocrine system that are parts of the ____, ____, and ____.
Term
pituitary gland
Definition
- hypophysis aka
Term
pituitary gland
Definition
- physically attached to hypothalamus by stalk
Term
pituitary gland
Definition
- physiologically attached to hypothalamus by blood vessels
Term
anterior pituitary gland
Definition
- adenohypophysis aka
Term
anterior pituitary gland
Definition
- contains epithelial glandular tissue
- contains pars distalis
- secretes hormones into surrounding capillaries
Term
posterior pituitary
Definition
- neurohypophysis aka
Term
posterior pituitary gland
Definition
- contains pars nervosa
- contains axons that produce and secrete two types of hormones
Term
pars distalis
Definition
- largest part of anterior pituitary
Term
pars nervosa
Definition
- largest part of the posterior pituitary gland
Term
pars distalis
Definition
- secretes hormones into surrounding capillaries
- contains 5 types of epithelial cells
Term
pars distalis
Definition
- secretes two different types of hormones
- contains axons
Term
anterior
Definition
- largest half of pituitary gland
Term
pituitary gland
Definition
- aka "master gland"
Term
pituitary gland
Definition
- function is controlled by the hypothalamus
Term
1. cortex
2. medulla
Definition
the adrenal gland consist of two distinct regions
1.____
2.____
Term
different
Definition
cortex and medulla have _____ embryological origins.
Term
cortex of adrenal gland
Definition
- outer region of adrenal gland
- underneath CT capsule
- divided into 3 zones
Term
steroid
- ex: cortisol
Definition
- hormones secreted by the cortex of the adrenal gland
Term
medulla of adrenal gland
Definition
- inner region of the adrenal gland
- functions like nervous system
Term
medulla of adrenal gland
Definition
- produces catacholamines such as epinephrine
Term
thyroid gland
Definition
- gland located in the neck
- consists of 2 lobes
- contains follicles
Term
simple
Definition
follicles have ____ epithelium consisting of follicular cells.
Term
follicular cells
Definition
- found in follicles
- surround colloid
- synthesize and secrete thryoid hormones
Term
thyroglobulin
Definition
- form of thyroid hormone stored in colloid
- extracellularly stored
Term
parafollicular cells
Definition
- surround colloid btwn follicular cells
- synthesize and secrete calcitonin
- do not make thyroid hormone
Term
calcitonin
Definition
- decreases blood calcium levels
Term
parathyroid gland
Definition
- located on thyroid gland
- usually 4 of them
- synethesize PTH
Term
PTH
Definition
- raises blood calcium levels
Term
pineal gland
Definition
- located within the brain
- contains cells that secrete melanin
- contains supporting cells
Term
pinealocytes
Definition
- cells that secrete melatonin
Term
glial cells
Definition
- function as supporting cells for pinealocytes
Term
integument
Definition
- skin + eccrine sweat glands + apocrine sweat glands + sebaceous glands
Term
epidermis
Definition
- stratified squamous keratinized epithelium
- contains nerves, ducts, no blood vessels
Term
dermis
Definition
- loose and dense irregular CT
- glands, blood vessels, nerves, hair follicles and smooth muscle
Term
hypodermis
Definition
- not part of skin
- loose CT and fat
Term
thin skin
Definition
- most of body
- thinner epidermis
- contains hair follicles, sebaceous glands, hair arrector pili muscles, eccrine sweat glands, and apocrine sweat glands
Term
thick skin
Definition
- palms and soles
- thicker epidermis
- contains no hair follicles, arrector pili muscle or sebaceous glands
- contains eccrine sweat glands, but not apocrine glands
Term
arrangement of keratinocytes in epidermis
Definition
- stratum corneum
- stratum lucidum
- stratum granulosum
- stratum spinosum
- stratum basale
Term
keratinocytes
Definition
- most numerous epithelial cell of epidermis
- arranged in 5 layers
Term
stratum basale
Definition
- single layer of keratinocytes resting on basale lamina
- mitotic cells of epidermis
- source of regenerated cells
Term
stratum corneum
Definition
- essentially dead keratinocytes filled with keratin
- nucleus and organelles are degraded
- layer shed from epidermis
Term
melanocytes
Definition
- produce skin pigmentation
Term
melanin
Definition
- functions as protection against UV radiation and pigmentation for skin
Term
langerhans' cells
Definition
- part of IR
- processes microbial antigens
Term
merkel cells
Definition
- associated with nerve endings
- ____ + nerve = noci or mechanoreceptors
Term
dense irregular
(collagen type I)
Definition
- CT layer of skin is ____
Term
eccrine sweat glands
Definition
- sweat is produced by secretory cells and released onto surface of skin by single duct
Term
apocrine sweat glands
Definition
- do not make sweat
- found in armpit and pubic area
- secrete mucin that empties onto skin through duct associated with hair follicle
- mucin + bacteria = stink
Term
sebaceous glands
Definition
- secrete sebum through hair follicle in thin skin
Term
sebum
Definition
- produces by sebaceous glands
- moisturizes hair and skin
Term
free nerve endings
Definition
- just an axon within epidermis
- functions as nociceptors
Term
merkel cell
Definition
- associated with sensory nerve to function as mechanoreceptor
Term
meissner's corpuscles
Definition
- mechanoreceptors distributed throughout skin
- especially in areas sensitive to touch (fingertips)
Term
paccinian corpuscle
Definition
- mechanoreceptor
Term
oral vestibule
Definition
- area outside teeth
Term
oral cavity proper
Definition
- area inside teeth
Term
oral competence
Definition
- ability to hold food and saliva in mouth
Term
mastication
Definition
- chewing
Term
deglutition
Definition
- swallowing
Term
1. oral competence
2. mastication
3. bolus prep
4. deglutition
5. speech
Definition
5 functions of oral cavity
Term
oral mucosa
Definition
- mucous membrane of oral cavity
- functions for protection, sensation and secretion
Term
mucosa
Definition
- means epithelium, basal lamina and loose CT (lamina propria)
Term
stratified squamous epithelium
Definition
- can be parakeratinized, orthokeratinized and nonkeratinized
Term
- keratinocytes
- melanocytes
- langerhans' cells
- merkel cells
Definition
- cells of oral mucosa
Term
keratinocytes
Definition
- most numerous cell of oral mucosa
Term
nonkeratinized
Definition
- cells have nuclei in ALL layers
Term
parakeratinized
Definition
- some cells have nuclei and others are anucleate
Term
orthokeratinized
Definition
- most similar to skin
- upper layers are anucleate
Term
lamina propria
Definition
- CT: cells (same as normal CT) and extracellular matrix containing collagen type I and elastic fibers
Term
submucosa
Definition
- layer of CT underneath lamina propria
- can be attached to muscle or bone
Term
lining mucosa
Definition
- nonkeratinized stratified squamous
- function as protection and nonspecific defense
- most in oral cavity
Term
masticatory mucosa
Definition
- parakeratinized and orthokeratinized stratified squamous epithelium
- functions to protect against forces of chewing
- found in gingiva and hard palate
Term
specialized mucosa
Definition
- has papillae, tastebuds, and keratinized stratified squamous epithelium
- specialized for sense of taste
- found on dorsal side of tongue
Term
hard palate
Definition
- masticatory mucosa
- lamina propria attached to bone
- lots of rete pegs
Term
soft palate
Definition
- lining mucosa
- nonkeratinized stratified squamous epithelium
- contains palatine minor salivary gland
Term
palatine minor salivary gland
Definition
- all mucous secreting gland in soft palate
Term
outer surface of lip
Definition
- stratified squamous keratinized
Term
red border
Definition
- junction of dry skin/moist mucosa
- keratinized epithelium with deep rete pegs
- blood vessels come close to skin
- doesn't have any glands
Term
labial mucosa
Definition
- lining mucosa
- minor labial salivary glands
Term
dorsal surface of tongue
Definition
- lingual papillae on anterior 2/3 of tongue
- specialized mucosa
Term
lingual papillae
Definition
- filiform
- fungiform
- foliate
- circumvallate
Term
filiform papillae
Definition
- most numerous type
- shaped like cones
- NO taste buds
- function mainly mechanical
- may function in aiding food back to throat or cleaning oral cavity and teeth
Term
fungiform papillae
Definition
- mushroom-shaped
- some tastebuds on surface
- blood vessels close to surface
- appear as red dots on tongue
Term
foliate papillae
Definition
- parallel ridges on lateral margins of posterior tongue oriented at right angles to long axis of tongue
- has tastebuds
Term
circumvalate papillae
Definition
- round structures arranged in V shape
- junction btwn anterior and posterior tongue
- largest papillae
- 100s of tastebuds
- function in taste
- associated with all serous secreting minor lingual salivary glands (von Ebner)
Term
serous glands of von Ebner
Definition
- found on circumvallate papillae
- all serous secreting minor lingual salivary gland
- serves as solvent for food molecules called "tastants"
Term
tastebuds
Definition
- contained within epithelium of fungiform, foliate, and circumvalate papillae
- also located on epiglottis, soft palate, larynx and oral pharynx
- sensory organ receptors for taste
Term
posterior 1/3 of tongue
Definition
- no lingual papillae/tastebuds
- lingual minor salivary glands
- tonsils in lamina propria
Term
ventral tongue
Definition
- no papillae/tastebuds
- nonkeratinized stratified squamous epithelium
- lining mucosa
- lamina propria directly attached to muscles of the tongue
Term
1. mucosa
2. submucosa
3. muscularis externa
4. adventitia/serosa
Definition
four layers of digestive tract, starting from lumen:
Term
chief cell
Definition
- located in stomach
- secretes pepsinogen
Term
pepsinogen
Definition
- secreted by chief cells
- changed to pepsin by stomach acid
Term
pepsin
Definition
- starts protein digestion
Term
parietal cell
Definition
- located in stomach
- secrete HCl to activate pepsin
- secrete gastric intrinsic factor
Term
HCl
Definition
- activates pepsinogen --> pepsin
Term
Gastric Intrinsic Factor
Definition
- absorbs vitamin B12
Term
gastric glands
Definition
- chief cells
- parietal cell
Term
enterocyte
Definition
- located in small and large intestine
- digestion and absorption of fats, proteins and carbohydrates
Term
paneth cell
Definition
- located in small intestine
- releases antibacterial agents in response to bacteria
Term
goblet cells
Definition
- located in the small and large intestine
- mucous-secreting cell that protects from acids
Term
- bile duct
- hepatic artery
- portal vein
Definition
three components of portal triad of liver
Term
- hepatocytes
Definition
liver cell
Term
bile caniculus
Definition
- two hepatocytes form this
- site where bile is first released
Term
sinusoid
Definition
- hepatocytes border on ____
- special type of blood vessel of liver
Term
- classical
- portal
- liver acinus
Definition
three lobules of liver
Term
classical/anatomic lobule
Definition
- lobules emphasizes endocrine function of liver
Term
portal lobule
Definition
- lobule emphasizes the exocrine function of the liver
Term
liver acinus
Definition
- used to explain liver pathology
Term
- exocrine: digestive enzymes --> ducts
- endocrine: hormones --> blood
Definition
difference between exocrine pancreas and endocrine pancreas
Term
exocrine pancreas
Definition
- digestive enzymes --> ducts
Term
endocrine pancreas
Definition
- hormones --> blood
Term
biliary tract
Definition
- consists of bile ducts from liver and gallbladder
- transports and releases bile into duodenum for digestion
Term
lymph
Definition
- seepage of fluid from blood
- tissue fluid
- primarily water
- contains lymphocytes
- transports antigens
Term
lymphatic system
Definition
- diffuse lymphatic tissue
- lymphatic nodules
- lymphatic organs
Term
bone marrow and thymus
Definition
- primary lymphatic organs
Term
lymph node and spleen
Definition
- secondary lymphatic organs
Term
diffuse lymphatic tissue
Definition
- accumulation of immune cells
- usually found in loose CT
- GALT, MALT, BALT
Term
lymphatic nodule
Definition
- groups of b-lymphocytes in CT
- contain immune cells that react to foreign molecules and destroy them
Term
bone marrow
Definition
- primary lymphatic organ
- location for b-cell maturation
- if b cells do not mature here, there will be no b cells
Term
thymus
Definition
- primary lymphatic organ
- site of t cell maturation and differentiation
- if this is missing, there will be no t cells
Term
thymus cortex
Definition
- site of immature t cells that cannot function in body
Term
medulla of thymus
Definition
- t-cells that can leave and function in body
Term
lymph nodes
Definition
- secondary lymphatic organ
- connected to lymphatic vessels
- filter lymph
- produce lymphocytes and antibodies
- store lymphocytes
Term
cortex of lymph nodes
Definition
- part of lymph node that contains lymphatic nodules w/lots of b cells
Term
deep cortex of lymph nodes
Definition
- part of lymph node that contains lots of t cells
Term
medulla
Definition
- part of lymph node that contains lots of plasma cells
Term
spleen
Definition
- secondary lymphatic organ
- largest lymphatic organ
- hemopoiesis in fetal development
- compensatory hemopoiesis in adults
- destruction of aged RBCs
- filtration of blood
- production of abys
- reservoir for RBCs and platelets
Term
white pulp of spleen
Definition
- has blood vessel called central artery
- lymphatic nodules with b cells
- periarterial lymphatic sheath (PALS) with t cells
Term
red pulp of spleen
Definition
- contains all types of blood and immune cells
- has capillary called splenic sinusoid
Term
blood
Definition
- antigens enter spleen from ____.
Term
white
Definition
antigens reach the central canal in the ____ pulp.
Term
b cells
Definition
____ cells are induced to proliferate into plasma cells.
Term
antibodies
Definition
plasma cells release ____ into circulation in the white pulp.
Term
conducting portion of respiratory system
Definition
- takes air from environment to lungs
Term
respiratory portion of respiratory system
Definition
- site of gas exchange
Term
c-shaped hyaline cartilage
Definition
- structure that keeps trachea lumen open
Term
plates of hyaline cartilage
Definition
- structure that keeps the bronchus open
Term
smooth muscle
Definition
- support for the wall of the bronchiole
Term
olfactory cell
Definition
- contains receptors for sense of smell
Term
conducting
Definition
- olfactory
- ciliated columnar
- goblet cell
- clara/bronchiolar cells
Term
ciliated columnar cell
Definition
- move material away from respiratory tract w/cilia
Term
goblet cell
Definition
- secretes mucus
- participates in mucociliary elevator
Term
clara/bronchiolar cell
Definition
- secrete some components of surfactant to reduce surface tension
Term
type I alveolar cell
Definition
- component of gas exchange barrier/ air-blood barrier
Term
type II alveolar cell
Definition
- produce/secrete all components of surfactant
Term
alveolar macrophage
Definition
- clear surfactant and debris from alveoli and respiratory bronchioles
Term
- bone marrow
- thymus
Definition
name the primary lymphatic organs:
Term
- thymus
- lymph node
Definition
name the lymphatic organs that are organized with a cortex and medulla:
Term
- lymph node
- spleen
Definition
name the secondary lymphatic organs:
Term
spleen
Definition
name the lymphatic organ organized as red pulp and white pulp:
Term
- spleen
- lymph nodes
Definition
name the lymphatic organs that have groups of lymphatic nodules:
Term
bone marrow
Definition
If this organ does not function properly, there won't be any b-cells throughout the body:
Term
lymph node
Definition
name the lymphatic organ that functions to filter lymph:
Term
spleen
Definition
name the lymphatic organ that functions to filter blood:
Term
thymus
Definition
if this lymphatic organ does not function properly, there will not be any t-cells throughout the body:
Term
spleen
Definition
name the lympatic organ that functions to destroy aged RBCs:
Term
renal corpuscle
Definition
- filtering unit of kidney
- produce filtrate of blood plasma
Term
glomerular filtration barrier
Definition
- allows proteins smaller than albumin to exit circulation
- prevents anionic proteins from leaving circulation
Term
proximal convoluted tubule
Definition
- reabsorbs glucose, amino acids, ions and vitamins back into surrounding kidney tissue
Term
loop of henle
Definition
- formation of urine
Term
distal convoluted tubule
Definition
- regulates urine pH
- controls Na/K levels
Term
macula densa cells
Definition
- measures concentration of Na in filtrate
Term
juxtaglomerular cells
Definition
- measure blood pressure in arterioles
- secrete renin if Na low
Term
collecting ducts
Definition
- collects urine from the distal convoluted tubule
Term
interstitial cells
Definition
- secrete erythropoietin
Term
erythropoeitin
Definition
- functions in RBC production
Term
gametogenesis
Definition
- production of sperm/ova
Term
oviduct
Definition
- picks up oocytes that are released from the ovary
Term
hormones
Definition
the endocrine system consists of endocrine glands that produce ____.
Term
receptors
Definition
cells must have ___ for the hormones in order to respond to them.
Term
target
Definition
hormones are carried from the cells that secrete them through CT or vascular system to ___ cells.
Term
hypothalamus, vascular
Definition
the pituitary gland is controlled by and physically attached to the ____, while physiologically attached by a ____ network.
Term
pars distalis
Definition
the adenohypophysis is made of epithelial glandular tissue and the ____ is the largest part.
Term
hypothalamus
Definition
the _____ controls the release of hormones from the pars distalis into surrounding capillaries.
Term
pars nervosa
Definition
which is the largest part of the neurohypophysis, which contains axons and also secretes 2 types of hormones?
Term
cortex, steroid
Definition
the ___ is the outer region of the adrenal gland underneath the tissue capsule and is divided into 3zones, each secreting a different ___ hormone.
Term
medulla, catecholamines
Definition
the ___ is the inner region, functioning like nervous system and producing ____ like adrenaline.
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