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Histology Exam 1 - Muscle
Muscle
30
Histology
Professional
09/18/2011

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Term
increase
Definition
effect of the sympathetic branch of the ANS on heart rate
Term
decrease
Definition
effect of the parasympathetic branch of the ANS on heart rate
Term
autorhythmic
Definition
neuronal activity is not required to initiate or maintain cardiac muscle contraction
Term
pacemaker region
Definition
contains cardiac cells that are spontaneously active; sets the contraction rate of the heart by initiating action potentials that propagate between cardiac cells
Term
cardiac myocyte
Definition
single nucleus, branched, interdigitations via intercalated discs
Term
gap junctions
Definition
electrically join cardiac muscle cells
Term
desmosomes
Definition
mechanically connect cardiac muscle cells
Term
thick filaments
Definition
formed by myosin bundles
Term
thin filaments
Definition
formed by F-actin and associated proteins of the tropomyosin and troponin complex
Term
sarcomeres
Definition
create striations in cardiac and skeletal muscle
Term
z-lines
Definition
areas found at the ends of each sarcomere where actin thin filaments attach to alpha actinin
Term
6
Definition
the number of thin filaments surrounding each myosin thick filament
Term
Ca2+
Definition
required for cardiac muscle contraction; binding of this element to the troponin complex regulates muscle contraction and relaxation
Term
ATPase
Definition
myosin head
Term
ATP binding to myosin head
Definition
required for dissociation of myosin head from actin filament to return to a state where it can bind to actin again
Term
inorganic phosphate (Pi) and ADP
Definition
produced through the binding of ATP to the myosin head
Term
dihydropyridine (DHP) receptors
Definition
voltage-gated Ca2+ channels
Term
opening of DHP receptors
Definition
initiated by membrane depolarization from positive charge being delivered to the gap between the T-tubule and sarcoplasmic reticulum
Term
ryanodine receptors
Definition
Ca2+ channels in the sarcoplasmic reticulum; bind Ca2+ and release it into the cell cytoplasm
Term
Ca2+-induced Ca2 release
Definition
initiated by Ca2+ binding to ryanodine receptors; primary source of Ca2+ for cardiac muscle contraction
Term
troponin complex
Definition
binds Ca2+ and initiates the sliding filament process
Term
muscle relaxation
Definition
initiated by decreasing cytoplasmic Ca2+ concentration and subsequent Ca2+ dissociation from the troponin complex
Term
characteristics of muscle tissue
Definition
irritability, contractility, extensibility, and elasticity
Term
types of muscle tissue
Definition
smooth, cardiac, and skeletal
Term
lightning bolt nuclei
Definition
artifact in smooth muscle tissue
Term
smooth muscle
Definition
locations: blood vessels, walls of viscera, capsule of spleen, skin, and pupil
Term
purkinje cells
Definition
modified cardiac muscle cells; increase conduction; subendothelial; large cells
Term
epimysium
Definition
fascia; external CT covering of muscle tissue
Term
perimysium
Definition
CT that wraps around muscle bundles
Term
endomysium
Definition
CT that wraps individual muscle fibers
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