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Histology Exam 1 - ANS
Autonomic Nervous System
47
Histology
Professional
09/17/2011

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Term
PNS
Definition
extremities
Term
CNS
Definition
brain, brainstem, and spinal cord
Term
grey matter
Definition
contains neuronal bodies
Term
white matter
Definition
contains nerves and ganglia
Term
homeostasis
Definition
balance between catabolism and anabolism; fluid balance and blood distribution; blood gas concentration and pH
Term
reflexive activity
Definition
unconscious
Term
reflex
Definition
a stereotyped motor response to a given sensory stimulus
Term
afferent and efferent neurons
Definition
peripheral components of the autonomic reflex arc
Term
central components of the autonomic reflex arc
Definition
spinal cord grey matter; the hypothalamus; the medulla oblongata
Term
parasympathetic and sympathetic
Definition
2 main divisions of the autonomic nervous system
Term
visceral motor system
Definition
another name for the autonomic nervous system
Term
Parasympathetic Division
Definition
"Rest and Digest"; associated with anabolism
Term
Sympathetic Division
Definition
"Fight or Flight"; associated with catabolsim
Term
paravertebral ganglia
Definition
"sympathetic chain ganglia", which compose the sympathetic chain/trunk
Term
Enteric Nervous System
Definition
regulated by sympathetic and parasympathetic input
Term
myenteric plexus
Definition
outer lining of GI organs
Term
submucosal plexus
Definition
within loose connective tissue of GI organs
Term
dual innervation
Definition
input and output balance between both parasympathetic and sympathetic divisions of the autonomic nervous system
Term
only sympathetic innervation
Definition
sweat glands, liver, spleen, most blood vessels, adrenal medulla
Term
Cholinergic Sympathetic Innervation
Definition
sweat glands in all domestic spp. (except horses) and blood vessels of skeletal mm.
Term
muscarinic receptors
Definition
cholinergic sympathetic postganglionic receptors
Term
ACh
Definition
neurotransmitter released by postganglionic cholinergic sympathetic neurons
Term
mimetic chemical
Definition
mimics a neurotransmitter
Term
lytic chemical
Definition
antagonizes a neurotransmitter
Term
adrenal medulla
Definition
links the sympathetic nervous system with the endocrine system
Term
chromaffin cells
Definition
cells within the adrenal medulla that share embryonic origin with ganglionic neurons; release epinephrine upon stimulation by sympathetic preganglionic neurons
Term
adrenal glands
Definition
responsible for the "Defense-Alarm Reaction" and circulating epinephrine
Term
ANS receptors
Definition
dictate the effect of neurotransmitters
Term
neurotransmitter effects on receptors
Definition
changes in ion permeability (ligand-gated ion channels); and changes in intracellular activity (second messenger sysstem)
Term
Nicotinic ACh Receptor (nAChR)
Definition
ligand-gated ion channel; excitatory to target
Term
acetylcholinesterase
Definition
inactivates nAChR and mAChR
Term
Muscarinic ACh Receptor (mAChR)
Definition
G-Protein linked channel; stimulatory or inhibitory
Term
M1 and M4
Definition
mAChR within the nervous system
Term
M2
Definition
mAChR inhibitory to cardiac m., conductile tissue, and sympathetic neurons
Term
M3
Definition
mAChR with parasympathetic GI effects; affects exocrine glands and endothelium
Term
nitric oxide (NO)
Definition
elicited by M3, after M3 activation by cholinergic sympathetic innervation in skeletal mm., to elicit vasodialation
Term
Norepinephrine (NE)
Definition
sympathetic post-ganglionic neurotransmitter
Term
Adrenergic Receptors
Definition
acted upon by norepinephrine
Term
MAO
Definition
monoamine oxidase
Term
alpha and beta
Definition
subtypes of adrenergic receptors
Term
Alpha 1 Adrenergic Receptors
Definition
excitatory to smooth mm. (splanchnic vessels, erector pili, GI sphincters)
Term
Alpha 2 Adrenergic Receptors
Definition
inhibitory to presynaptic neurons and parasympathetic neurons
Term
Beta 1 Adrenergic Receptors
Definition
excitatory to cardiac m. and conductile tissue
Term
Beta 2 Adrenergic Receptors
Definition
inhibitory to smooth mm.
Term
Signs of Horner's Syndrome
Definition
miotic pupil, enophthalmos, third eyelid protrusion, ptosis, and hyperhidrosis (in horses)
Term
Signs of loss of sympathetic input
Definition
ipsilateral vasodilation and denervation supersensitivity
Term
Denervation Supersensitivity
Definition
adrenergic receptors on sweat glands
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