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Histology Exam 1
Lecture 8 (Bone Tissue)
22
Other
Not Applicable
06/09/2008

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Term
Bone
Definition
- vascularized
- innervated
Term
Methods of Examining Bone
Definition
- H/E Stain
- Ground bone section
Term
Four Cells Associated with Bone Tissue
Definition
- Osteoprogenitor Cells
- Osteoblasts
- Osteocytes
- Osteoclasts
Term
Osteoprogenitor Cells
Definition
- Derived from mesenchymal cells
- become osteoblasts
Term
Osteoblasts
Definition
- Derived from Osteoprogenitor cells
- post-mitotic cells
- mononucleated cells on surface of bone
- form bone
- secrete osteoid
- calcify/mineralize oisteoid into mineralized bone matrix
- create new bone during embryogenesis
- remodel existing bone
- repair bone fractures
Term
Osteocytes
Definition
- osteoblasts encased in mineralized bone matrix
- found inside bone
- maintain bone
- does not make bone
Term
Osteoclasts
Definition
- derive from blood monocytes
- cannot form from osteoprogenitor cells, osteoblasts or osteocytes
- multinucleated
- on surface of bone
- destroy/remodel/resorb bone
Term
Compact Bone
Definition
- solid mineralized bone found around outer edges
Term
Cancellous Bone
Definition
- trabeculae for irregular framework surrounding marrow tissue with circulating blood
Term
Red Bone Marrow
Definition
- produces red/white BCs and platelets
- replaced by yellow as we age
Term
Yellow Bone Marrow
Definition
- contains fat and connective tissues
- produces some WBCs
Term
Osteons
Definition
- compact bone is organized into this
- aka Haversian Systems
Term
Central Canal
Definition
- contains blood vessels, lymph vessels and nerves
- surrounded by bone containing osteocytes
Term
Lamellar Bone
Definition
- AKA Osteons of Compact Bone arrangement
Term
Trabeculae
Definition
- thin plates of bone that form irregular framework in Cancellous Bone
- aka Spicules
- spaces between contain marrow tissue w/blood
Term
Periosteum
Definition
- dense irregular CT
- covers outer surface of bone
- anchored to bone by Sharpey's Fibers
- connects bone to tendons/ligaments
Term
Osteogenesis
Definition
- intramembranous
- endochondral
- both form bone of same histological structure
- both replace rep-existing connective tissue w/bone
Term
Intramembranous Ossification
Definition
- bone formation directly from mesenchyme - maxilla and mandible - alveolar bone
Term
Endochondral Ossification
Definition
- from hyaline cartilage
- long bones
- require hyaline cartilage model
- mesenchyme in region differentiates into hyaline cartilage
-
Term
articular cartilage
Definition
- hyaline cartilage remaining on ends of bone
Term
epiphyseal plate
Definition
- two strips of hyaline cartilage
- responsible for continued increase in length of bone
- eventually close and stop growing
Term
Mandibular Condyle
Definition
- only part of mandible formed by endochondral ossification
- source of post-natal growth of mandible
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