Term
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Definition
| Skeletel support, protect vital organs, house marrow, store minerals |
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Term
| Two types of bones, macroscopically |
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Definition
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Term
| Parts of a typical long bone |
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Definition
| diaphysis, medullary, physis, metaphysis |
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Term
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Definition
| ends of bone covered by hyaline cartilage |
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Definition
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Term
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Definition
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Term
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Definition
| new bone between diaphysis and epiphysis |
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Term
| first cell to develop from osteoprogenitor |
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Definition
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Term
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Definition
| bond surface, resembling epithelial layer |
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Term
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Definition
| matrix closest to osteoblasts, not yet calcified, collagen rich. |
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Term
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Definition
| mature bone cells. maintain extracellular matrix. |
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Term
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Definition
| multinucleate giant cells involved in resorption. |
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Term
| extracellular matrix: 2 components |
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Definition
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Term
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Definition
| synthesized by osteoblasts and cytes; collage type I and ground substance. |
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Term
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Definition
| responsible for rigidity of bone. Calcium, phosphate, etc. |
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Term
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Definition
| complex of concentric lamellae (aka osteon) |
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Term
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Definition
| tiny canals radiating from each lacuna, serve as channels for nutrient transport |
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Term
| Structure of Compact bone |
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Definition
| numerus osteons between outer and inner circumferential lamellae |
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Term
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Definition
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Term
| Structure of Cancellous bone: |
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Definition
| anastomosing spicules, trabeculae, thin plates of osseous bone. No recognizabel Haversian systems. |
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Term
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Definition
| connective tissue membrane; outer fibrous layer and inner celullar layer |
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Term
| Is there periosteum at the articular surfaces of bones? |
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Definition
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Term
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Definition
| lines bone marrow spaces and trabeculae of cancellous bone. Single layer of cells - osteoprogenitors, osteoblasts, osteoclasts, and connective tissue |
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Term
| intramembranous ossification |
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Definition
| bone forms directly from mesenchymal connective tissue |
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Term
| endochondral ossification |
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Definition
| bone forms indirectly, via a cartilage model |
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Term
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Definition
| non-calcified pre-osseous tissue |
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Term
| the frontal and parietal bones in the skull develop by: |
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Definition
| Intramembranous ossification |
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Term
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Definition
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Term
| primary bone is characterized by: |
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Definition
| random deposition of fine collagen fibers, lower mineral content, high osteocytes. |
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Term
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Definition
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Term
| secondary bone is characterized by: |
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Definition
| lamellae between rows of lacunae, organized into Haversian systems |
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Term
| the periosteal bud is composed of |
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Definition
| blood vessels from the periosteum, mesenchymal cells all invading the degenerating cartilage |
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Term
| the primary center of ossification is established when |
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Definition
| the periosteal bud reaches the degenerating midsection of the cartilage model |
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Term
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Definition
| bone trabeculae with calcified cartilage cores |
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Term
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Definition
| cartilage cores have been replaced by lamellar bone |
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Term
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Definition
| chondrocytes form columns of stacked cells parallel to long axis of bone |
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Term
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Definition
| large chondrocytes, matrix reduced to thin septa between chondrocytes |
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Term
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Definition
| chondrocytes die, capillaries and CT invade lacunae at base of cell columns |
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Term
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Definition
| osteoblasts form, deposit bone on calcified cartilage |
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Term
| osteoclasts are acidophilic or basophilic? Why? |
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Definition
| acidophilic; abundant lysosomes, Golgi, mitochondria |
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Term
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Definition
| acid phosphates, collagenase, other enzymes |
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Term
| a resorption lacuna is aka |
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Definition
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Term
| bone has more or less GAG than cartilage? |
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Definition
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Term
| during intramembranous ossification, the perichondrium becomes the |
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Definition
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Term
| during primary ossification, calcified cartilage appears _________ and primary bone appears __________ |
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Definition
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Term
| during endochondral ossification, the process of ossification spreads toward the _________ of the future bone. |
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Definition
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Term
| secondary centers of ossification appear when? |
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Definition
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Term
| why are there no isogenous groups in bone? |
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Definition
| the hard matrix does not allow for interstital growth. |
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Term
| what is the brush border of an osteoclast? |
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Definition
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Term
| waht are the two purposes of bone resporption? |
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Definition
| remodelling, Ca++ homeostasis |
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Term
| what do haversian canals contain? |
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Definition
| capillaries, lympatics, nerves |
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Term
| what holds adjacednt osteons together? |
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Definition
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