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Histology block-2 Lymph
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13
Histology
Graduate
02/11/2011

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Term
Lymph Capillaries
Definition
thin-walled vessels lined with endothelium

clefts between endothelial cells
- incomplete basement membrane

end blindly in extracellular spaces, retrieve lymph
Term
Lymphatic Vessels
Definition
large lumen comparatively

Valves to prevent backflow
Term
Lymphatic Ducts
Definition
similar to veins, except more smooth muscle in media
Term
Lymph Nodes: Outer vs Inner(deep) Cortex
Definition
Outer Cortex - B Cells

Inner(deep) cortex - T cells
Term
Path of flow through lymph node
Definition
Enters through Afferent lymphatic vessel
>>>
subcapsular sinus
>>>
paratrabecular(cortical) sinuses
>>>>
medullary sinus
>>>>>
efferent lymphatic
Term
Lymph Node: Medulla
Definition
medullary sinuses between medullary cords.

cords are aggregations of diffuse lymphoid tissue
Term
Diffuse Lymphoid Tissue
Definition
Free cells(lymphocytes) of lymphoid tissue

lymph nodes, spleen, tonsils, digestive, respiratory.
Term
Lymphoid Nodules
Definition
Found in cortex of lymph nodes and in white pulp of spleen

Primary Nodule: rounded collection of tightly packed small lymphocytes

Secondary nodule: spherical cluster of larger pale staining cells.
Term
Blood Vessels path in Lymph Nodes
Definition
enter and leave at the hilus and run in trabeculae(through cortex)

Blood can enter lymp nodes through high endothelial venule
Term
Spleen has White pulp and Red Pulp
Definition
White pulp- Lymphoid tissue: lymphocytes, plasma cells, macrophages.

Central Artereis pass into pulp from trabeculae

Red Pulp: rich in blood. Contains sinuses surronded by splenic(billroth) cords.

Supporting meshwork filled with macrophages, blood elements and plasma cells
Term
Blood Vessel Course in Spleen
Definition
Enters at hillus
>>>>>
trabecular artery
>>>>>
Central Arteries(white pulp)
>>>>>
Penicillus(red pulp)
>>>>
venous(splenic) sinuses
>>>>
pulp vein, trabecular vein, splenic vein
Term
Functions of Spleen
Definition
Storage and destruction of blood cells and platelets

production of: lymphocytes, antibodies

hemoglobin degradation and iron stored in macrophages
Term
Thymus
Definition
Medulla is continuous from one lobule to the next.

Each lobule has its own cortex

Function: Releases hormones responsible for Differentiation and maturation of T cells
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