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Histo embryology final
study for histo embryo final
67
Health Care
Professional
02/25/2008

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Cards

Term
Is cementum thicker apically or cervically?
Definition

 Apically

(also thick in interradicular areas)

10-15 microns cervically

50-200 microns apically 

Term
What is the definition of cementum?
Definition
A hard avascular connective tissue covering roots of teeth; like bone but bone is vascular
Term
What are 3 roles of cementum?
Definition
  1. Covering root dentin (covering dentinal tubules)
  2. Site of attachment for periodontal fibers
  3. Compensate for resorption (maintains height lost to resorption)
Term
T or F: cementum resportion is abnormal
Definition
True
Term
How is cementum similar to bone?
Definition
  • Lacunae w/ cementocytes within
  • Canaliculi
  • Incremental lines (aka resting lines) produced from continuous phasic deposition of cementum - NOT EXACTLY REMODELING, BONE REMODELS, CEMENTUM DOES NOT
Term
How do bone and cementum differ?
Definition
  • Not vascularized
  • Minor ability to remodel
  • Resist resorption (due to lack of vascularization)
  • Lacks neural component thus no pain
  • 70% bone is inorganic (cementum only 45-50%)
  • 2 unique cementum molecules CAP (cementum attachment protein) and IGF
Term
Describe the steps in the development of cementum:
Definition
  • HERS induces underlying ectomesenchymal cells of the pulp to differentiate into odontoblasts and secrete predentin
  • HERS becomes interrupted
  • Ectomesenchymal pulp cells come into contact with predentin and differentiate into cementoblasts
  • Cementoblasts lay down cementum
Term
What are 3 theories of how cementoblasts are activated to lay down cementum?
Definition
  1. Dental follicle cells may receive reciprocal signal from HERS or dentin to differntiate into cementoblasts
  2. HERS cells differentiate directly into cementoblasts
  3. Possible role of epithelial cell rests of Malassez
Term
What is the most common type of collagen in cementum, dentin and bone
Definition
Type I collagen
Term

From where does intermediate cementum (hyaline layer of Hopewell-Smith) originate?

Where is it located?

It's function?

It's composition?

Definition
  • It originates from HERS before it disintegrates; functions to seal dentinal tubules;
  • found between the granular dentin layer of Tomes and the secondary cementum (origin cementoblasts)
  • Mineralized greater than adjacent dentin or secondary cementum 
Term
List properties and chemical composition of cementum
Definition

Pale yellow

More permeable than other dental tissues

45-50% hydroxyapetite (inorganic) [bone has higher inorganic content]

50-55% collagenous and non-collagenous organic matrix proteins 

Term
What are three methods of classifying cementum?
Definition
  1. Presence or absence of cells
  2. Prefunctional and functional
  3. Origin of collagenous fibers of the matrix
Term
Where are acellular and cellular cementum most likely found and why?
Definition
  • Acellular (primary) - found along the majority of the root; does not require cells where cementum is thin because the fluid that bathes these cells keeps it viable
  • Cellular (secondary) - near apex and interradicular; found where cementum is thicker to maintain viabilitiy cellular usually overlies acellular
Term
What is cementoid?
Definition

Young matrix that becomes secondarily mineralized

Cementoid + hydroxyapetite = cementum 

Term
What are two major differences between cellular and acellular cementum?
Definition
  1. Cells and no cells
  2. Acellular has slow growth and incremental lines are relatively close together; cellular grows fast and lines are far apart
Term
What are the two origins of collagen fibers in the organic matrix of cementum?
Definition
Sharpey's fibers (PDL) and cementoblasts
Term
Differentiate between intrinsic, extrinic, and mixed collagen fibers of cementum:
Definition
  • Extrinisc - derived from Sharpey's fibers (periodontal ligament); perp. or oblique to root surface
  • Intrinsic - derived from cementoblasts - parallel to root surface and right angles to extrinsic fibers
  • Mixed - area with both intrinsic and extrinsic 
Term
Describe the distribution of types of cementum on the root:
Definition

Acellular afibrillar near CEJ

Acellular extrinisic: cervix to nearly whole root; inc in thickness near apex

Cellular: apical 1/3 and furcations 

Term
Describe the OMG rule at the CEJ
Definition

Cementum overlaps enamel 60%

Cementum meets enamel 30%

Gap between cementum and enamel 10% 

Term
What are some consequences of aging for cementum?
Definition
  • Becomes irregular due to calcification of ligament bundles where they attach to calcium
  • Continuous deposition of cementum in apical area (+ Maintains tooth height; - blocks apical foramen)
  • Cementum resorption followed by deposition creating reversal lines
  • Resorption of root dentin replaced through cemental repair
Term
What are cementicles?
Definition

Single or multiple calcified round or ovoid nodules found in the PDL; found free in the ligament and attached or embedded in cementum; due to injury or age

Term
With a loss of cementum what else is lost?
Definition
Attachment
Term
Cemental repair occurs when?
Definition
After resorption of root dentin or cementum due to trauma; reparative cementum restores attachment
Term
What happens to cementum and alveolar bone during orthodontic movement?
Definition
Cementum resists resorption so is maintained which alveolar bone resorbs and remodels to move the teeth
Term
If cementum has no innervation why may a patient experience sensitivity following a scaling and root planing?
Definition
If cementum is removed the dentin is exposed and can be painful
Term
When does the alveolar process start developing?
Definition
During tooth eruption
Term
What are the layers of bone in the alveolar process?
Definition
  • Bundle bone (aka alveolar bone proper) - (closest to tooth lining alveolus)
  • Central spongiosa - standard bone w/ volkman and haversian canals
  • Outer cortical plate - lamellar w/ haversian systems
Term
Describe bundle bone (alveolar bone proper).
Definition
  • May be perforated by Sharpey's fibers of the PDL or may be just compact bone
  • Sharpey's fibers would be perpindicular or oblique to the bundle bone
  • Appears more radiodense because of inc. mineral content around bundles - called lamina dura in xrays
  • Perforated by foramina transmitting nerves and vessels
Term
Where is the alveolar crest found?
Definition

1.5-2 mm below level of the CEJ

Slanting of the crest is indicative of perio disease and bone loss

Term
What happens when a tooth doesn't have an antagonist?
Definition
Osteopenia, resorption of the alveolar bone, because of inactivity of the tooth
Term
What are some characteristics of the PDL?
Definition

Thinnest midroot

Thickness from .15 to .38 mm

Width decreases w/ age b/c of inc. production of cementum

High turnover rate

 

Term
When does the PDL form and from what?
Definition
Forms from the dental follicle shortly after the root
Term
Where is acellular afibrillar cementum located and what is its role?
Definition

Near the CEJ

Lacks collagen so it has no role in attachment

May be a developmental anomaly 

Term
Where is acellular extrinsic fiber cementum located, what is its function, and origin of fibers?
Definition

Located from cervical margin to apical third

Functions in anchorage

Fibers originate extrinsically

Principal tissue of attachment

Term
What is the origin, location, and function of cellular intrinsic fiber cementum?
Definition

Intrinsic fibers

Middle to apical third and furcations

Adaptation (maintain occlusal height) and repair (cemental damage) 

Term
What is the origin, location, and purpose of secondary cellular mixed fiber cementum?
Definition

Fiber origin is intrinsic and extrinsic with extrinsic being thicker (5-7 microns) and intrinsic being (1-2 microns)

Bulk of secondary cementum

Located in apical portion and furcations

For adaptation 

Term
What is the function of oxytalan fibers?
Definition

Regulate vascular flow in relation to tooth function

Run obliquely from cementum to blood vessels

Most numerous in cervical area 

Term
What are the purposes of the PDL?
Definition
  • Shock absorber
  • Tooth support
  • Proprioception
Term
Which dentoalveolar fibers are most numerous?
Definition
Oblique fibers
Term
What is origin of each dentoalveolar fiber?
Definition

Alveolar crest group: below CE junction, downward and outward

Horizontal group: apical to ACG; right angle to root

Oblique group: oblique direction attaching coronally to bone

Apical group: apex base of socket

Interradicular group: 

Term
What is the origin of each gingival ligament fiber?
Definition

Dentogingival - cementum to f/a gingiva

Alveologingival - alveolar bone to f/a gingiva

Circular - completely in gingiva around neck of tooth

Dentoperiosteal -  runs apically from the cementum over the outer cortical plate to alv. process or vestibule (muscle) or floor of mouth

Transseptal - cementum between adjacent teeth over alveolar crest 

Term
What is most numerous gingival ligament fibers?
Definition

Dentogingival

 

 

Term
In terms of blood supply to the PDL, what major vessels does it originate from, and in what areas of the mouth is it most prominent?
Definition

Derived from the superior and inferior alveolar arteries

Posterior > anterior

Mandibular > maxillary 

Term
In terms of nervous supply to PDL, where does it originate and in which portion of the tooth does it predominate?
Definition
Derived form the inferior and superior alveolar nerves and found mostly in the apical region
Term
What are major characteristics of the interstitial space of the periodontium?
Definition

Present between fiber and containing the nerve and vascular supply

Lots of ground substance here to withstand masticatory forces  (70% water)

Dermatan sulfate is major glycosaminoglycan 

Term
What happens to the PDL when funtion is reduced?
Definition

PDL narows and fiber bundle number and thickeness decreases

Primarily due to inc. cementum deposition 

Term
What are the four stages of the eruptive tooth stage?
Definition
  1. Root formation
  2. Movement
  3. Penetration
  4. Occlusal contact
Term
Teeth are constantly moving in the preeruptive phase. What are the two types of movement?
Definition
  • Total bodily movement
  • One portion remains fixed and the rest moves leading to changes in the tooth germ
Term
What happens to the tissue directly over an erupting tooth?
Definition
Blood vessels and nerves degenerate and macrophages destroy cells and fibers through hydrolytic enzymes
Term
What is the gubernacular cord? And canal?
Definition

CT overlying successional tooth that connects with the lamina propria of oral mucosa by means of a fibrous CT that contains remnants of dental lamina;

Canal widens and allows the cord to pass --> canal is seen lingual to primary teeth

Term
What are the rates of intraosseous and extraosseous tooth movement
Definition

Intraossesous 1 - 10 microns/day

Extraossesous 75 microns/day 

Term
What is cleidocranial dysplasia?
Definition
When clavicles are not present or hypoplastic and there are multiple unerupted teeth
Term
What are the theories of tooth eruption?
Definition
  • Root formation
  • Bone remodeling
  • Dental follicle attracts osteoclasts which initiate bone remodeling
  • Traction power of fibroblasts of PDL
Term
What are four factors controlling mesial drift?
Definition
  1. Contraction of transseptal fibers
  2. Adaptability of bone tissue
  3. Anterior compartment of occlusal force
  4. Pressure from soft tissue
Term
Differentiate between active and passive eruption?
Definition
Active is to compensate for occlusal/incisal wear and passive is gradual recession of gingiva and alveolar bone; both lead to longer crown
Term
Where are osteoclasts derived from?
Definition
monocyte-macrophage lineage
Term
Where are the minor salivary glands (generally) and are they putting out mixed, serous, or mucous secretions?
Definition
Term
Rank parotid, submandibular, and sublingual gland in terms of size and percentage of total salivary output.
Definition

Parotid - largest - 25% of output

Submandibular - intermediate size - 60% output

Sublingual - smallest - 5%

Term
Which minor salivary glands are purely serous?
Definition
Von Ebners located below the sulci of the circumvallate and foliate papillae
Term
Where in the oral cavity are minor salivary glands not found?
Definition
  • Anterior hard palate
  • Gingiva
Term
Where are the Weber and Blandin-Nuhn minor salivary glands found?
Definition

Weber - posterior lateral tongue

Glands of Blandin-Nuhn - ventral tongue 

Term
What gives saliva its buffering capacity?
Definition
Bicarbonate and phosphate ions
Term
What does the lactoferrin in saliva do?
Definition
Binds free iron to deprive bacteria of it in order to enhance antimicrobial properties of saliva
Term
How does saliva maintain tooth integrity?
Definition
Facilitates ionic exchange of calcium and phosphate ions
Term
What is the embryologic origin of the salivary glands and order of development?
Definition

Parotid - ectoderm

Sublingual and submandibular - foregut endoderm 

 

Parotid - 4-6 weeks

Submandibular 6 weeks

Sublingual and minor glands 8-12 weeks 

 

Differentiate ectomesenchyme --> fibrous capsule --> septa 

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