Term
| Functions of Integument (PREMISE) |
|
Definition
Protection - dessication, bacteria, etc
excretion
Regulation - Temperature, Water balance
Excretion - Through Glands
Metabolism - Fat storage, VitD synthesis
Immune - provides info to lymph system
Sensation - Touch, Pressure, Pain, temp
Endocrine - Secretes hormones, cytokines |
|
|
Term
|
Definition
(1) Epidermis - Outer layer, Avascular, Keratinized Stratified squamous
(2) Dermis - Deeper layer, Vascular - Dense irregular connective
(3) Hypodermis - underlies Skin, loose areolar CT, (superficial fascia) permits movement of skin |
|
|
Term
| Thick Skin, Characteristics |
|
Definition
Palms and Soles
Thick epidermis - thick keratinzed layer
High dermal papillae(adhesion of dermis/epidermis) Fingerprints
Numerous Sweat glands |
|
|
Term
| Thin Skin, Characteristics |
|
Definition
Thin epidermis and keratin Layer
Hair follicles |
|
|
Term
| Layers of skin, Deep to Superficial |
|
Definition
Stratum Basale
Stratum Spinosum
Stratum Granulosum
Stratum Lucidum
Stratum Corneum |
|
|
Term
|
Definition
single layer of basophilic Columnar
Contains stem Cells which develop into Keratinocytes
Desmosomes and Hemi-Desmosomes
(with tonofilaments)
Intermediate Filaments(cytokeratins) (cell to cell adhesion)(Tonofilaments) |
|
|
Term
|
Definition
Polyhedral cells bearing processes(spines)
keratinzation begins
Intermediate filaments form bundles(tonofibrils) |
|
|
Term
|
Definition
Produce lamellar bodies/granules forms lipid sheet. Prevents desication.
80% of cell evenlope is loricrin
Keratohyalin granules: Promote aggregation of keratin fibers. Contain flagrin and trichohyalin |
|
|
Term
|
Definition
thin layer that appears clear in thick skin.
Granules, nuclei and organelles not present |
|
|
Term
|
Definition
| Several layers of flat dead cells |
|
|
Term
|
Definition
Precursor cells originate in neural creset
Produce Melanin, released from processos
Located under Stratum Basale |
|
|
Term
|
Definition
stellate(star shape) located in epidermis (spinosum)
take up antigens then present to lymphoid cells
contact allergic response in skin and delayed hypersensitivity |
|
|
Term
|
Definition
Papillary layer: Papillae, thin C.T. fibers, nerve endings, capillaries
Reticular Layer: Deeper main portion, Denser C.T., Muscle fibers, fat |
|
|
Term
|
Definition
subpapillary plexus: Thin branches loop upwards into papillae. Between Papillary and reticular layer
Cutaneous plexus: Supply's hair follicles and glands. Between Hypodermis and dermis.
Atriovenous shunts: Bypass capillaries, thermoregulation |
|
|
Term
|
Definition
Meissner corpuscles: In Papillae. Touch.
Merkel cell: In basale Touch. Neural crest
Free endings: No myelin, Pain and Temp
Peritrichial endings: around hairs, detect movement. |
|
|
Term
|
Definition
Eccrine: Common, merocrine. deep in dermis/hypodermis. Duct double cuboidal. Duct loses wall and spirals through epidermis.
Apocrine - Connect to hair follicles. . Puberty, Underarms, pubic area, areola. |
|
|
Term
|
Definition
Dermis next to hair follicles.
Oil/sebum into hair follicles.
Stratified Epithelium.
Holocrine |
|
|
Term
|
Definition
Fetal to Adult:
- collagen fibres thicken, collagen synthesis decreases
- elastic fibres increase in number and thickness
- elastin in adult is five times the amount in fetus
Adult to Old Age:
- cross linking of collagen fibres, loss of elastic fibres
Solar Elastosis:
- caused by excessive exposure to sun
- skin becomes fragile, loses suppleness, develops wrinkles |
|
|
