Term
| cardinal features connective tissue |
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Definition
support other basic type tissues
widely separated cells- abundant extracell matrix
-viscosity/tensile strength vary with location |
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Term
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Definition
embryonal: mesenchyme and mucous-contain amorphous ground substance made of hyaluronic acid (wharton jelly of umbilical cord)
adult: loose/dense (reg/irreg)/elastic/adipose |
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Term
| functions of Connect tissue |
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Definition
structural support: bone/cart and tend/ligaments
medium for exchange: blood supplies nutrients to cells/tissues of organs/remove waste
defense/protection |
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Term
| constituents of connective tissue |
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Definition
| cell/matrix/fiber/ground substance |
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Term
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Definition
derive from mesenchyme
-produce extracell matrix material
-form cell adhesion mechanisms to react w extracell matrix
examples: fibroblast/macrophage(immune system)/mast cell (allergic rxn histamine hipocrin)/plasma cell(antibody)/ chondrocytes (cell for cartilage)/osteoblast (bone-produce lots extracll matrix collagen)/ myofibroblasts/adipocytes |
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Term
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Definition
most common found CT cell
-actively secrete connect tissue matrix
-irreg branch cytoplasm
-pale large nucleus
-rich in RER and Golgi (collagen is protein) |
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Term
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Definition
small cell-few processes
less developed rer golgi
can convert into fibroblast |
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Term
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Definition
phagocytic activity
*derive from monocyte precursors in bone marrow
*rich in lysosomes
histiocyte in conn tiss/kupffer in liver/dust cell in lung/osteoclast/microglial cell in CNS
*ACT AS ANTIGEN PRESENTING CELLS |
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Term
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Definition
modified lymphocytes produce antibodies
-not seen in healthy tissue- seen in mucosa
-eccentric nucleus with dispersed chromatin "Cart Wheel Appearance) |
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Term
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Definition
fat cell-abundant in adipose tissue
-white fat adipocytes large contain single central fat vacuole
-periphery cytoplasm
-flat compressed nucleus against cell membrane |
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Term
| multilocular adipose tissue |
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Definition
brown fat
prominent in new born
metabolize fat to produce heat in new born (high mitochond density)
lost in childhood |
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Term
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Definition
numerous granules for heparin(anticoagulant-life saving drug in stroke) (chondroitin sulphate)
-granules contain histamin, neutral protease, eosinophil chemotactic factor
-produce number of mediators from membrane: leukotrienes/thromboxanes/prostaglandins |
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Term
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Definition
hay fever
bronchial asthma
hyperallergenic persons
anaphylactic shock |
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Term
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Definition
| collagen/reticular/elastic |
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Term
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Definition
3 amino acids make protein: glycine/proline/hydroxyproline
hydroxylation of proline accomplished by vitamin c- make h bond allow callagen to bend
-secrete as procallagen- balance supply/demand then cleaved by peptidase for polymerization into collagen fibril
-triple helix alpha chains secreted by fibrobast - assemble into cross link fibers/bundles |
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Term
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Definition
type 1: resist force/tension/stretch
*bone, tendon, dentin, skin
type 2: resist to intermitt press
*cartilage, intervertebral disc |
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