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HFF2 Test #1
Blood, Cardiovacular, EKG
100
Medical
Undergraduate 1
01/12/2014

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Term
Functions of Blood
Definition
Distribution
Regulation
Body Protection
Term
Distribution
(Blood Transports?)
Definition
*O2 from lungs & nutrients from digestive
*Metabolic waste from cells to lungs & kidneys
*Hormones from endocrine glands
Term
Regulation
(Blood Maintains)
Definition
*Body Temps
*pH in body tissues
*Liquid Vol in circulatory system
Term
Protection
(Blood prevents blood loss by?)
Definition
*Activating plasma proteins & platelets
*Initiating clot formation
Term
Protection
(Blood Prevents Infection By?)
Definition
*Utilizing antibodies
*Activating WBC
Term
Physical Characteristics
(Averg. Vol. of Blood)
Definition
Males: 5-6L
Females: 4-5L
(Normalvolemia)
Term
Hypovolemia
Definition
Low Blood Vol.
Term
Hypervolemia
Definition
High Blood Vol.
Term
pH of Blood
Definition
7.35-7.45, x=7.4
Term
Osmolarity
Definition
300 mOsm or 0.3 Osm
(This value reflects the concentration of solutes in the plasma)
Term
Salinity of Blood
Definition
0.85%
(Reflects concentration of NaC1 in blood)
Term
Temp of Blood
Definition
38'c
Term
Blood accounts for what % of body weight?
Definition
8%
Term
What kind of tissue is blood?
Definition
Connective Tissue
Term
2 Major Components of Blood
Definition
Liquid=Plasma (55%)
Formed Elements (45%)
Term
What are formed elements?
Definition
RBC
WBC
Platelets
Term
What are platelets?
Definition
Fragments of megakaryocytes from bone marrow
Term
Hematocrite Levels
Definition
Males: 47% (+- 5%)
Females: 42% (+-5%)
Term
Components of Plasma
Definition
Water: 90-92%
Proteins: 6-8%
Organic Nutrients: Glucose, Carbs, Amino Acids
Electrolytes: Sodium, Potassium, Calcium, Chloride
Nonprotein Nitrogenous Sustance: Lactic acid, urea
Respiratory Gases: O2 CO2
Term
What Proteins are in Plasma?
Definition
*Albumins: Maintain osotic pressure
*Globulins
*Fibrinogen: Clotting protein
Term
Are WBC's complete cells?
Definition
YES
Term
Are RBC's complete cells?
Definition
NO
No nuclei, organelles & platelets are just cells fragments
Term
Most blood cells do NOT divide but are renewed by cells in bone marrow
Definition
Term
RBC's
Definition
Biconcave Disc
Flexible
Anucleate (No cell division)
Circulate 120 days
Filled w/ Hb (97% of cells contents)
Hb functions in gas transport
Term
Most numerous of the formed elements
Definition
Males: 5.2-5.8mil cell/cubic millimeter
Females: 4.3-5.2mil cell/cubic millimeter
Term
RBC's Function
Definition
Respiratory gas transport
Term
Oxyhemoglobin
Definition
Hemoglobin bound to O2
(Happens in lungs)
Term
Deoxyhemoglobin
Definition
Hb after O2 diffuces into tissues
Term
Carbaminohemoglobin
Definition
Hb bound to CO2
(happens in tissues)
Term
Hematopoiesis
(Blood Cell Formation)
Definition
Occurs in red bone marrow
(Myeloid tissue)
Term
RBC Disorders
Definition
*Polycythemia- Abnormal excess of RBC's
*Anemia- Blood has low O2 carrying capacity
Term
Anemia: Insufficient RBC's
Definition
Hemorrhagic Anemia
Hemolytic Anemia
Aplastic Anemia
Term
Anemia: Decreased Hb Content
Definition
Iron Deficiency Anemia
Pernicious Anemia
Term
Anemia: Abnormal Hb
Definition
Thalassemia
Sickle Cell Anemia
Term
WBC's
(Only blood components that are complete cells)
Definition
4800-10000 cubic millimeter
Many are phagocytic
Term
2 Major Types of WBC's
Definition
Granulocytes: Neutrophils, Eosinophils, Basophils
Agranulocytes: Monocytes, Lymphyocytes
Term
Leukocytosis
(WBC count >11000/mm3)
Definition
Normal response to bacterial/viral invasion
Term
Leukopenia
Definition
Decrease in WBC count below 4800/mm3
Term
Leukemia
Definition
Cancer of WBC's
Term
Granulocytes: Neutrophils
Definition
*Major component of pus
*60% of total WBC
Term
Agranulocytes: Lymphocytes
Definition
*30% or more of WBC
*Most important cell of immune system
*2 Tyes (T & B cells)
Term
Leukocytes Disorders
Definition
Leukemia
* Cells are numerous but nonfunctional
*Leukemias are names according to the abnormal WBC's involved
Term
Mononucleosis
Definition
Epstein Barr virus infects B lymphocytes & salivary glands
"Kissing Disease"
Term
Lymphoma
Definition
Neoplasm of lymph nodes, tonsils, spleen & lymph fluid
Term
Clotting
Definition
Injury causes thrombocytes to aggregate & tissues release thromboplastin
Term
Fibrinogen converted to fibrin=
Definition
Clot
Term
Thrombosis
Definition
Clotting
Term
Thrombus
Definition
A clot
Term
Embolus
Definition
Traveling Clot
Term
Infarction
Definition
Tissue death from clot getting lodged in vessel
Term
Hemophilia
Definition
Genetically inherited from mother to male child
Term
Allergy
Definition
Immune system overreacts
Term
Autoimmune
Definition
Reacts to self
Term
Immune Deficiency
Definition
HIV, SCID
Term
Autoimmune Rheumatic Fever
Definition
SS: Myocarditis 1-4 wks after strep
D: No definitive
T: Antibiotics
Term
Autoimmune Rheumatoid Arthritis
Definition
SS: Common in women > 40, ulnar deviation
D: Physcial symptoms, ESR Increased
T: Corticosteroids
Term
Autoimmune Myasthenia Gravis
Definition
SS: Muscle fatigue, decreased resp function
D: Antibodies acetyocholine receptors
T: Cholinergics
Term
Autoimmune SLE
Definition
SS: Butterfly rash, joint pain
D: Antibody Test
T: Corticosteroids
Term
Autoimmune Scleroderma
Definition
SS: Hardening of connective tissue
D: Physcial Symptoms
T: Immune Suppressors
Term
SCID
Definition

Severe Combines Immunodeficiency Syndrome
*Defect in B & T Cells

"Bubble Boy"

Term
Normal Values CBC
Hgb
Definition
Males: 13.5-18 g/dL
Females: 12-16 g/dL
Term
Normal Values CBC
Hct
Definition
36-54%
Term
Normal Values CBC
PT
Definition
10 -13 sec
Term
Normal Values CBC
RBC's
Definition
4.2-6.3 mill/mL
Term
Normal Values CBC
WBC's
Definition
4500-11000 mill/mL
Term
Normal Values CBC
PLT
Definition
150000-350000 mL
Term
Normal Values CBC
Granulocytes & Agranulocytes
Definition
Neut- 60%
Lymph- 25%
Mono- 10%
Eos- 3%
Baso- 2%
Term
Normal Values CBC
Sed Rate ESR
Definition
<20mm/hr
Term
Cardiovascular Systems Function
Definition
Trasport Blood
Term
3 Types of Blood Vessels
Definition
Arteries(Arterioles)
Capillaries
Veins(Venules)
Term
Function of Arteries
Definition
Take blood away from heart
Term
What is the largest artery?
Definition
Aorta
Term
Function of Veins
Definition
Take blood to the heart
Term
What is the blood flow sequence?
Definition
Superior & inferior vena cava~ R atrium~ tricuspid valve~ R ventricle~ pulmonary trunk & arteries to lungs~ pulmonary veins leaving lungs~ L atrium~ bicuspid valve~ L ventricle~ Aortic semilunar valve~ aorta~ to the body
Term
2 circuits in the cardiovascular system
Definition
Pulmonary Circuit (blood to lungs)
Systemic Circuit (blood to rest of body)
Term
Blood Pressure
Definition
Force exerted by circulating blood Vol. on walls of artery during circulation
Term
Systolic Pressure
Definition
High when heart expels blood, peroid of contractions of both atrial & ventricles
Term
Diastolic Pressure
Definition
Occurs when all heart chambers are relaxed
Term
Systole
Definition
Contraction of heart chambers
Term
Normal heart rate?
Definition
60-100bpm
Term
Varicose veins
Definition
Develop when the valves of veins become weak
Term
Phlebitis
Definition
Inflammation of a vein that can lead to blood clots & possible death
Term
Automaticity
Definition
Ability to trigger electrical impules w/o being stimulated by another source
Term
SA (sinoatrial) Node
Definition
Initiates the heartbeat & causes the atria to contract on average every 0.85 sec
Term
AV (Atrioventrical) Node
Definition
Conveys the stimulus & initiates contraction of ventricles
Term
ECG (Electrocardiogram)
Definition
A recording of electrical changes that occur in the myocardium during cardiac cycle
Term
Holter Monitor
Definition
Portable EKG that records heart activity 24/7
Term
Stress Test
Definition
EKG records while patient exercises
Term
Echocardiogram
Definition
Sound waves transmitted through heart to look for structural/functional abnormalities
Term
Angiogram
Definition
xray w/ contrast media
Term
Cardiac Catheterization
Definition
Insertion of a catheter to visualize hearts activity, measure pressure and look for blockage
Term
Cardiovascular Disease (CVD)
Definition
Leading cause of death in western countries
Term
Atherosclerosis
Definition
Due to a build-up of fatty material (plaque), mainly cholesterol, under inner lining of arteries
Term
Congenital Heart Disease
Definition
Born with a defect in left & right side of heart
Term
Heart murmur
Definition
Valves are narrowed so blood rushes around before closing
Term
Congestive Heart Failure
Definition
Blood accumulates in ventrices causing edema in body or pulmonary circuit
Term
Hypertension (high bp)
Definition
20% of Americans suffer from hypertension
Term
Hypertenstion is present when?
Definition
Systolic pressure is 140 or greater or Diastolic pressure is 100 or greater
Term
What are healthy levels for Cholesterol, LDL< HDL and trig?
Definition
Cholesterol <200
LDL <100
HDL >50
trig <200
Term
What are Epinephrine, Beta blockers, Digitalis, Morphoine and Nitroglycerin used for?
Definition
Epinephrine- Increase BP
Beta Blockers- Reduce BP
Digitalis- Increase cardiac output
Morphine- Pain
Nitroglycerin- Smooth muscle relaxant
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