Term
HSV1
- type
- primary cell target
- incubation
- site of latency
- means of spread
- clinical manifestations |
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Definition
Type: α
Primary cell target: mucoepithelial cells
Incubation: 2-12 days
Site of latency: neurons (trigeminal)
Means of spread: close contact
Symptoms:
- gingivostomatitis
- herpetic whitlow
- keratoconjunctivitis
- herpes encephalitis |
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Term
HSV2
- type
- primary cell target
- incubation
- site of latency
- means of spread
- clinical manifestations |
|
Definition
Type: α
Primary cell target: mucoepithelial cells
Incubation: 2-12 days
Site of latency: neurons (sacral)
Means of spread: sexual transmission & close contact
Symptoms:
- genital herpes
- neonatal herpes |
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Term
Epstein-Barr virus (EBV)
- type
- primary cell target
- incubation
- site of latency
- means of spread
- clinical manifestations |
|
Definition
Type: γ
Primary cell target: oropharyngeal epithelial cells, B-cells
Incubation: 30-50 days
Site of latency: B-cells
Means of spread: saliva
Clinical manifestations:
- infectious mononucleosis
- Burkitt's lymphoma
- nasopharyngeal carcinoma
- oral hairy leukoplakia
- lymphoproliferative syndromes |
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Term
Varicella zoster virus (VZV)
- type
- primary cell target
- incubation
- site of latency
- means of spread
- clinical manifestations |
|
Definition
Type: α
Primary cell target: mucoepithelial cells
Incubation: 10-14 days
Site of latency: neurons
Means of spread: respiratory and close contact
Clinical manifestations:
- chicken pox
- shingles
- post-herpetic neuralgia |
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Term
Cytomegalovirus (CMV)
- type
- primary cell target
- incubation
- site of latency
- means of spread
- clinical manifestations |
|
Definition
Type: β
Primary cell target: monocytes, lymphocytes, epithelial cells
Incubation: 4-6 weeks
Site of latency: monocytes, lymphocytes
Means of spread:
- secretions: saliva, urine, semen, blood, milk
- transfusions
- tissue transplant
- congenital
Clinical Manifestations:
- cytomegalic infusion disease
- mononucleosis
- CMV opportunistic disease
- retinitis |
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Term
Human herpes virus 6 (HHV6)
- type
- primary cell target
- incubation
- site of latency
- means of spread
- clinical manifestations |
|
Definition
Type: β
Primary target cell: T-cells
Incubation: 5-10 days (roseola)
Site of latency: T-cells
Means of spread:
- saliva
- urine
- blood
- probably genital secretions
Clinical manifestations:
- exanthem subitum (roseola, 6th disease)
- febrile syndrome w/o rash in infants |
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Term
Human herpes virus 7 (HHV7)
- type
- primary cell target
- incubation
- site of latency
- means of spread
- clinical manifestations |
|
Definition
Type: β
Primary cell target: T-cells
Incubation: ?
Site of latency: T-cells
Means of spread: saliva
Clinical manifestations:
- exanthem subitum (roseola, 6th disease) |
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Term
Human herpes virus 8 (HHV8)
- type
- primary cell target
- incubation
- site of latency
- means of spread
- clinical manifestations |
|
Definition
Type: γ
Primary cell target: lymphocytes, others
Incubation: ?
Site of latency: unknown
Means of spread: close contact (sexual), possibly saliva
Clinical manifestations:
- Kaposi's sarcoma |
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