| Term 
 | Definition 
 
        | MOA: may have affinity for GABAa receptor may be agonist for adenosine A1 receptor
 
 uses: insomnia, anxiety
 
 A/E: headache, dizziness, GI upset, fatigue morning after
 
 C/I: pregnancy, breastfeeding
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | MOA: inhibits reuptake of serotonin, NE, DA 
 uses: depression, anxiety, sleep disorders, nerve pain related to HSV
 
 A/E: photosensitivity, anxiety, dry mouth, dizziness, GI upset, fatigue, sexual dysfunction
 |  | 
        |  | 
        
        | Term 
 
        | C/I: Pregnancy, breastfeeding |  | Definition 
 
        | EVERYTHING but: arnica
 cranberry
 echinacea
 ginger
 
 (So these can't have it happen):
 Valerian
 St. John's Wort
 Saw palmetto
 milk thistle
 licorice
 horse chestnut seed extract
 hawthorn
 gingko
 feverfew
 black cohosh
 aloe vera
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | MOA: inhibits 5 alpha reductase, blocks androgen receptor in prostate, blocks alpha 1 receptors, inhibits components of IGF-1 signalling pathway, anti-inflammatory 
 uses: BPH, chronic pelvic pain in women
 
 A/E: GI upset, breast tenderness, decreased libido
 
 C/I: hormone-dependent cancers
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | MOA: antioxidant, reduces inflammatory LTs, helps transcribe liver proteins 
 uses: liver and GB disease
 antidote to Amanita mushroom poisoning
 
 A/E: mild GI/diarrhea, may lower blood sugar
 
 C/I: allergy to plants in aster/daisy/sunflower family
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | MOA: releases endogenous secretin, which increases mucous coating in GI tract 
 uses: gastric/duodenal non-H. pylori ulcer
 bronchitis
 sore throat
 hepatitis
 
 A/E: GI, diarrhea
 |  | 
        |  | 
        
        | Term 
 
        | Horse Chestnut Seed Extract |  | Definition 
 
        | MOA: inhibits elastase and hyaluronidase, which breaks down collagen in capillary walls 
 uses: chronic venous insufficiency
 varicose veins
 hemorrhoids
 
 A/E: itching, nausea, GI upset
 
 C/I: raw or homemade preps!! these contain *ESCULIN*, which is toxic; diabetes, hypoglycemia, <18 yo
 
 interactions: diabetes meds
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | MOA: dilates coronary vessels, increases HR, diuretic, anti-oxidant 
 uses: mild CHF, angina, HTN
 
 A/E: headache, nausea, dizziness, palpitations
 
 C/I: children
 
 ineractions: may potentiate anti-arrhythmics, inotropes, b-blockers, cardiac glycosides
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | MOA: anti-oxidant anti-inflammatory
 inhibits platelet aggregation
 induces vasodilatin
 possible neuroprotective effect
 
 uses: Alzhemier's, dementias, memory enhancement, intermitten claudication (calf pain), impotence, MS, tinnitus, vertigo
 
 A/E: dizziness, GI, allergic dermatitis
 
 C/I: raw or cooked seeds!! they contins **____TOXIN**, which can cause seizures, death
 
 interactions: drugs metabolized by cyp450, anti-coagulants, anti-platelets, NSAIDs, trazodone
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | MOA: phenolic and sesquiterpene compounds, which have anti-emetic, anti-inflammatory, anti-platelet props, increases GI motility 
 uses: N&V, motion sickness, osteoarthritis, low back pain
 
 A/E: heartburn, dermatitis
 
 C/I: allergy, gallstones, bleeding problems
 
 interactions: anti-coagulants, anti-platelets, some chemotherapy meds
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | MOA: anti-inflammatory, anti-paltelet, anti-tumor; maybe via parthernolide, a sesquiterpene lactone 
 uses: migraine prophylaxis, RA, cancer
 
 A/E: GI upset, oral irritation
 
 C/I: allergy to plants in aster/daisy/sunflower family
 
 interactions: anti-coagulants, NSAIDs, anti-platelets, thrombolytics
 |  | 
        |  | 
        
        | Term 
 
        | What has anti-inflammatory effects? |  | Definition 
 
        | aloe vera arnica
 echinacea
 feverfew
 ginger
 gingko
 milk thistle (reduces inflammatory LTs)
 saw palmetto (but first think androgen blocker)
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | MOA: anti-inflammatory, activates macrophage cytotoxic activity against microorganisms and tumor cells 
 uses: (orally) cold, flue, URI; (topically) boils, acne
 
 A/E: rash, asthma, anaphylactic in allergies, GI upset
 
 C/I: allergy to plants in aster/sunflower/daisy/chrysanthemum/ragweed, autoimmune diseases
 
 interactions: immunosuppressant drugs
 |  | 
        |  | 
        
        | Term 
 
        | C/I: allergy to plants in aster/daisy/sunflower family |  | Definition 
 
        | Arnica Echinacea
 Feverfew
 Milk thistle
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | MOA: acidifies urine and prevents E. coli bacteria adherance to bladder wall 
 uses: UTI, ulcer causes by H. pylori, dental plaque
 
 A/E: GI upset, diarrhea
 
 C/I: none
 
 interactions: none
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | EVERYTHING but (these DON'T cause it): aloe vera
 arnica
 ginger
 hawthorn
 
 
 (These cause it)
 black cohosh
 cranberry
 echinacea
 feverfew
 gingko
 horse chestnut seed extract
 licorice
 milk thistle
 saw palmetto
 St. John's wort
 Valerian
 |  | 
        |  | 
        
        | Term 
 
        | treats ulcers caused by H. pylori |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | treats non-H. pylori ulcers |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | MOA: partial agonist on serotonin receptors; no known estrogen properties 
 uses: menopausal symptoms, irregular menses, PMS, labor induction
 
 A/E: headache, dizziness, (rare) hepatotoxic
 
 C/I: liver disease
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | MOA: has helenalin, a sesquiterpene lactone, which is anti-inflammatory, anti-carcinogenic 
 uses: muscle sprain/strain, contusion, hematoma, osteoarthritis
 
 A/E: (topical) contact dermatitis, irritation, burning
 
 C/I: DO NOT USE ORALLY!!; allergy to plants in the aster/daisy/sunflower family; do not use on borken or damaged skin
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | MOA: anti-inflammatory, increases collagen content of granulation tissue 
 uses: (topically) burns, diabetic ulcers, skin lesions, insect repellant; (orally) esophageal, gastric/intestinal irritation, ulcverative colitis, constipation, diabetes
 
 A/E: (oral) abdominal cramping, diarrhea, may decrease blood sugar
 
 C/I: (topical) contact allergy; (oral) pregnancy, breastfeeding
 
 interactions: diarrhea caused by laxative effect may dcrease absorption of other meds
 |  | 
        |  | 
        
        | Term 
 
        | topical for burns, diabetic ulcers, other skin lesions |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | arnica (helenalin) feverfew (parthenolide)
 ginger
 |  | Definition 
 
        | herbals and their sesquiterpene lactones |  | 
        |  | 
        
        | Term 
 
        | raw/homemade preps contain **ESCULIN** |  | Definition 
 
        | horse chestnut seed extract |  | 
        |  | 
        
        | Term 
 
        | releases endogenous secretin |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | C/I: liver disease A/E: hepatotoxicity
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | treats liver and GB disease |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | antidote to Amanita mushroom poisoning |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  |