Term
| What type of vaccine is Hepatitis B ? |
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Definition
| Recombinant. Other recombinant vaccines are HPV and S. typhi. Ag are produced via a yeast cell |
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Term
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Definition
| It varies. Better in infants with 98-100% after 3 doses, than in adolescents and adults with 90-95%. |
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Term
| Which vaccines ares stored at 2-8C? |
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Definition
| Hep A, Hep B and Tetanus, Diphteria and Pertussis. |
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Term
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Definition
| The most common viral infection. 300 million are chronic carriers. 1/3 of pop with evidence of past or continuing infection. 15-25% of infected will die of liver causes (cirrhosis or HCC). Causes 80% of HCC. 1 mill people die/yr of diseases related to HBV infection. |
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Term
| HBV, who has more risk of chronic disease? |
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Definition
| Children. They are less symptomatic than adults, but have a much higher risk of developing chronic infection |
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Term
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Definition
| sex, blood transfusion, perinatal (+F in L-MIC, especially in mother HBeAg+). 50-100 times more infectious than hiv |
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Term
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Definition
6.5% prevalence in IDU
1.5 in pregnant women |
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Term
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Definition
| Pakistan 2006. Prevalence of 8.3%. RF id was receiving > than 10 medical injections in previous year (Quddus) |
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Term
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Definition
| non medical injections (2003 Pakistan). Low knowledge and awareness of HBV among pregnat women |
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Term
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Definition
| Endemic in China and SEA with 8-20% of people with chronic infection. Central Asia with 2-7% prev of chronic infection |
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Term
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Definition
Increased level of HBV DNA
In people tx with ART, reconsitution syndrome may reactivate HBV with
People signifacnt liver damage
People antiHBc postive who are infected with HIV have higher rate of reactivation of HBV
Livr related mortality 17X higher in HIV infected (MACS) |
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Term
| Methods of HBV diagnosis? |
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Definition
RPHA: reverse passive hemaglutination
EIA: Enzyme immunoassay
RAI: radioimmunoassay |
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Term
|
Definition
+F: perinatal
non-medical injections
IDU
blood transfusions |
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Term
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Definition
| Yes, bu 100-1000 fold lower concentration than in blood. |
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Term
| What is the effect of HBV on HIV infection?d |
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Definition
| Rate of serconversion to HIV 2 fold higher in MSM HBV infected (MACS). |
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