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8% of body wt in kg convert lbs to kg by / by 2.2 .08 x 70kg 5.6L |
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| low number of normal red blood cells |
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| plasma is more than 2 liters of coke |
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| white cells less than 1% and platelets |
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90% water 7g/100 ml bld 7% plasma ( protein) =70g/L |
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| 60% of plasma proteins and maintains plasma volume by osmotically drawing water into bld stream |
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| blood clotting proteins - 5% of plasma proteins |
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35% of plasma proteins a globulins transport High Density Lipoproteins b globulins transport low density lipoproteins and transferrin g globulins - produce antibodies |
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| y globulins gamma globulins |
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Definition
synthesized by lymphocytes IgG act on bacteria and other foreign agents IgE act on Allergens |
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| too low -HIV chemotherapy |
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| too high fighting infection |
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| granular leukocytes polymorphonuclearcytes |
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Definition
granular, multilobed, produced in red bone marrow neutrophils , eosinophils,basophils |
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| produce histamine and heparin (anticoagulant) |
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| organic molecules in blood in blood plasma |
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Definition
glucose 70-120 cholesterol <200mg |
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Definition
| NH3, urea BUN, uric acid, creatine, bilirubin |
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| NA+, K+, Ca+2, HCO3 (buffer) |
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| blood plasma w/o clotting proteins |
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| genetic inability to synthesize blood clotting proteins |
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may have recognition site proteins called antigens 5million /mm3 blood |
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| transport O2 &CO2 by binding to hemoglobin |
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Definition
| produced in red bone marrow of vertebrae & rib cage. live for four months |
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Definition
| hormone released in kidneys stimulates erythropoeisis in bonemarrow |
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| degeneration of red bone marrow |
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Definition
| blood platelets (cell fragments) produced in red bone marrow. Stimulated by Thrombopoietin hormone from the liver. |
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| reticulo-endothelial system |
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Definition
| the spleen and liver filter out old damaged RBC |
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Term
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Definition
1. vascular spasm 2. formation of blood platelet plug via platelet adhesion and aggregation. 3. formation of Fibrin Protein Clot (coagulation) |
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| formation of fibrin protein clot |
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Definition
1. intrinsic pathway: bld platelets,platelet factor,prothrombinase 2. Extrinsic pathway: injured tissue cells, tissue factor, prothrombinase common pathway: prothrombin + ( prothrombinase +Ca2)=thrombin. thrombin+ fibrinogen= fibrin clot |
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to dissolve clot plasminogen (made in liver) + TPA (released from healing cells) =plasmin =fibrinolysis |
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Definition
WBC 7,000/ mm3 blood leukopenia / leucocytopenia/lower than normal HIV chemotherapy leukocytosis higher than norma, fighting off infection |
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Term
| polymorphonuclearcytes/ granular leukocytes |
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Definition
granular leukocytes are multilobed. 60% of WBC are neutrophils attack bacteria eosinophils - allergic reactions basophils - release histamine -inflammation and release heparin - anticoagulant |
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Definition
monocytes - macrophages- large phagocytes lymphocytes 25%( leukocytes /WBC) org. lymph B lymphocytes -org. Bone marrow T lymphocytes - org Thymus gland |
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synthesize & release immunoglobulins (bacteria) precipitation & agglutination- clumping opsonization - marking for phagocytosis lysis- activating Tc cells to lyse foreign body |
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Th helper T Cells release interferon release cytokines- activate B lymphocytes to ... Tc cytotoxic T cels -release perforin |
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Agglutinogens(antigens on surface of RBC) + Agglutinins (antibodies in plasma) cause . . . |
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| release heparin and histamine |
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Definition
| basophils (a type of granular leukocytes /WBC ) |
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| all involved in allergic reactions |
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Definition
| eosinophils, b lymphocytes, Th Helper T lymPhocytes, basophils, Tc Cytotoxic lymphocytes |
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| increases capillary permeability |
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| phagocytize antigen-antibody complexes in allergic reactions |
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Definition
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| when B lymphocytes come in contact with foreign agents they transform into |
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Definition
| plasma cells that release antibodies |
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| basophils are also called |
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Definition
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| monocytes that leave the bloodstream |
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Definition
| enter the tissue as macrophages |
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