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HEME ONC PANCE
Heme Onc word assoc for PANCE
44
Other
Graduate
05/30/2012

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Cards

Term
Philadelphia chromosome
Definition
CML
Term
Auer rods
Definition
AML
Term
Reed-sternberg cells
Definition
Hodgkin’s lymphoma
Term
Painless LAD (us. Neck or axilla), LAD in orderly fashion; “B” signs + pruritis; splenomegaly; LN pain after drinking alcohol
Definition
Hodgkin’s lymphoma
Term
Fatigue, PM sweats, weight loss, painless LAD or neck mass
Definition
Lymphoma – do Lymph node biopsy. Bone marrow Bx and CT scan used for staging
Term
Painless LAD us. Scattered. “B” signs
Definition
Non-Hodgkin’s lymphoma
Term
Howell-Jolly bodies
Definition
sickle-cell
Term
Hx HTN, nephrotic syndrome, CRF or Renal insufficiency. Know CBC.
Definition
Anemia
Term
PICA, Pregnant & fatigue, Menstruation. Cheilosis
Definition
Fe Deficiency Anemia
Term
Anemia after colectomy, partial gastrectomy. Glossitis, decreased vibratory sensation
Definition
B12 or Pernicious anemia
Term
G6PD + Quinidine, Nitrofurantoin, Sulfa
Definition
Hemolytic anemia
Term
Fatigue, weakness, low fever, purpura, pallor, gingival bleeding. No HSM
Definition
Aplastic anemia
Term
Elevated Hgb, Hct, splenomegaly, post showering pruritis, plethora, engorged retinal veins
Definition
Polycythemia vera; Tx = Phlebotomy
Term
Splenectomy
Definition
Pneumococcal vaccine
Term
Sickle cell
Definition
Autosomal Recessive, pain in extremities after exercise, priaprism
Term
Spontaneous Hemarthrosis
Definition
Hemophilia A
Term
Mucosal or gingival bleeding, epistaxix, menorrhagia
Definition
Von Willebrand disease
Term
Continuous bleeding post-op or trauma. Given multiple blood transfusions. Low platelets, increased PT, INR, + fibrin split products (increased d-dimer)
Definition
DIC
Term
treat Fe def anemia until ??? is normal?
Definition
ferritin
Term
Inc ferritin, lo serum iron
Definition
Anemia of Chroninc Dz
Term
Acute Chest Syn
Definition
sickle cell
Term
Beta Thal Major
Definition
only HbF and HbA2
Term
Beta Thal Minor
Definition
Inc HbA2, basophilic stipling
Term
Age of swtich from HbF to HbA
Definition
4 to 6 mos
Term
BARTS
Definition
4 chain Alpha Thal, hypdrops fetalis
Term
Fava beans or ASA then hemolysis
Definition
G6PD Def
Term
(+) Coombs test
Definition
autoimmune hemolytic anemia
Term
Hemolytic anemia lab to monitor
Definition
haptoglobin
Term
(+) Schilling test
Definition
Vit B12 def
Term
hypersegmented neutrophils
Definition
Pernicious Anemia (autoimmune loss of Intrinsic Factor, no B12 absorption)
Term
child, post virus, petechial hemms, mucosal bleed
Definition
ITP
Term
bleed after minor cut, gums/nares/GI/GU bleed, superficial bruises, petechiae, NO hemarthroses
Definition
Platelet defect
Term
deep tissue bleed, NO bleed with minor cut, NO petechiae, (+) hemarthroses/hematomas, severe post-sx bleed
Definition
Clotting Factor Disorder
Term
h/o nose bleed as child, excessive bleed after dental cleaning, NO bruises/petechiae
Definition
vWF Def
Term
hemolytic anemia, severe thrombocytopenia, seizures, schistocytes and helmet cells on smear
Definition
TTP
Term
systemic thrombosis and hemorrhage; sepsis, major trauma, major surgery, post-delivery; transplant rejection
Definition
DIC
Term
Factor VIII Def
Definition
Hemophilia A
Term
Factor IX Def
Definition
Hemophilia B
Term
Chronic DIC
Definition
pancreatic CA
Term
Children Leukemia
Definition
ALL
Term
Bence-jones proteinria
Definition
Multiple Myeloma
Term
Hodg B sympts
Definition
night sweats, F, wt loss, total body puritis, pain in enlarged node after etOH
Term
Blasts >20% in marrow or circulating
Definition
Acute classification
Term
smudge cells
Definition
CLL
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