Term
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Definition
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Term
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Definition
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Term
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Definition
| Increased numbers of immature RBCs |
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Term
| What is the energy source for RBCs? (be specific) |
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Definition
glucose
(90% anaerobically degraded to lactate, 10% by HMP shunt) |
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Term
| What is the life span of a RBC? |
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Definition
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Term
| What are the names of and what's contained in the 2 types of granules found in thrombocytes? |
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Definition
Dense granules (ADP, calcium)
α granules (vWF, fibrinogen) |
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Term
| Life span of a thrombocyte |
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Definition
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Term
| What is the vWF receptor on thrombocytes (platelets)? |
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Definition
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Term
| What is the Fibrinogen receptor on thrombocytes (platelets)? |
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Definition
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Term
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Definition
| basophils, eosinophils, neutrophils, monocytes, and lymphocytes |
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Term
| Which leukocytes are granulocytes? |
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Definition
| basophils, eosinophils, and neutrophils |
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Term
| Which leukocytes are mononuclear cells? |
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Definition
| Monocytes and lymphocytes |
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Term
| What are the azurophilic granules in Neutrophils and what 4 enzymes are found in them? |
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Definition
Lysosomes:
Hydrolytic enzymes
Lysosyme
Myeloperoxidase
Lactoferrin (binds iron and inhibits growth of phagocytosed bacteria and some fungi) |
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Term
| 2 diseases in which you may see hypersegmented neutrophils: |
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Definition
| Vitamin B12 and folate deficiency |
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Term
| What is the cell surface marker for macrophages? |
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Definition
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Term
| What do eosinophils have that helps fight helminths? |
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Definition
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Term
| What 3 chemicals are found in the basophilic granules of basophils? |
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Definition
Heparin (anticoagulant)
Histamine (vasodilator) and other vasoactive amines
Leukotrienes (LTD4) |
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Term
| When Mast cells degranulate, what 4 things are released? |
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Definition
Histamine
Heparin
Tryptase
Eosinophil chemotactic factors |
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Term
| What is a major difference between Basophils and Mast cells? |
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Definition
| Basophils are found in the blood, Mast cells are found in tissue |
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Term
| What drug prevents mast cell degranulation? |
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Definition
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