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HEME CLUES
CLUES YO
138
Histology
Post-Graduate
12/16/2011

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Term
NEURTORPHIL
Definition
THE PHAGOCYTE - MOST ABUNDANT - ANTIMICROBIAL
Term
EOSINOPHIL
Definition
PARASITE DESTROYER - ALLERGY INDUCER
Term
BASOPHIL
Definition
ALLERGY HELPER - IGE RECEPTOR - HISTAMINE RELEASE
Term
MONOCYTE
Definition
THE DESTROYER - MP (HYDROLYTIC ENZYMES, COFFEE BEEN NUCLEUS (CD 4 -> TISSUE -> CD14 GRADUATE IN LEVEL)
Term
LYMPHOCYTE
Definition
THE WARRIOR - T B NK CELLS
Term
PLATELET
Definition
THE CLOTTER - NO NUCLEI, SMALLEST CELL
Term
BLAST
Definition
BABY HEMATOPOIETIC CELL
Term
BAND
Definition
BABY NEUTROPHILS - COMES OUT WITH THE GANG AS BACK UP IN FIGHT
Term
HIGH WBC N' HIGH PMNS
Definition
STRESS DEMARGINATION
Term
HIGH WBC AND <5% BLASTS
Definition
LEUKEMOID REACTION, SEEN IN BURN PT - EXTREME DEMARGINATION (LOOKS LIKE LEUKEMIA ALMOST)
Term
HIGH WBC AND >5% BLASTS
Definition
LEUKEMIA (WHEN <5% ITS ACTUALLY A LEUKEMOID REACTION)
Term
HIGH WBC N' BANDS TELL YOU?
Definition
LEFT SHIFT - HAVE AN INFECTION
Term
HIGH WBC N' B CELLS?
Definition
BACTERIAL INFECTION
Term
DISEASES WITH HIGH EOSINOPHILS
Definition
NAACP - NEOPLASMS, ALLERGY/ASTHMA/ADDISONS DISEASE (RELATIVE ESOINOPHIL DUE TO LACK OF CORTISOL CALLING THEM), COLLAGEN VASCULAR DISEASE (CAN'T MARGINATE), AND PARASITES
Term
DISEASE WITH HIGH MONOCYTES >15%
Definition
STELS - SYPHILIS (CHANCRE, RASH, WARTS), TB (HEMOPTYSIS, NIGHT SWEATS), EBV (TEENAGER SICK FOR MONTH), LISTERIA (BABY SICK, BAD MILK), SALMONELLA (FOOD POISONING)
Term
HIGH RETIC >1% TELL YOU?
Definition
RBCC BEING DESTROYED PERIPHERALLY (BM NO AFFECTED)
Term
LOW RETIC TELL YOU?
Definition
BM AFFECTED, NOT WORKING RIGHT, DOWN PRODUCTION
Term
WHAT IS POIKILOCYTOSIS
Definition
DIFFERENT SHAPES
Term
ANSIOCYTOSIS?
Definition
DIFFERENT SIZES
Term
CYTOSIS 'N CYTHEMIA?
Definition
HIGH LEVELS OF STUFF
Term
DIFF BETWEEN PLASMA N' SERUM?
Definition
PLASMA - NO RBC, HAS CLOTTING FACTORS

SERUM - NO RBC OR FIBRINOGEN
Term
WHAT IS CGD?
Definition
CHRONIC GRAN DZ, LOW COMPLEMENT DISEASE, NADPHA OXIDASE DEF - RECURRENT STAPH/ASPERGILLUS INFECTIONS - NITROBLUE TTZ STAIN IS NEGATIVE
Term
WHAT IS MPO DEF CAUSE?
Definition
CATALASE +VE INFECTIONS
Term
CHEDIAK HIGASHI
Definition
LAZY LYSOSOME SYNDOMRE - LYSOSOMES ARE SLOW TO FUSE AROUND BACTERIA
Term
ORGAN CAN MAKE RBC IF BONES FAIL?
Definition
SPLEEN - CAUSES SPLENOMEGALY
Term
WHAT CAUSES A SHIFT TO THE RIGHT IN HB CURVE?
Definition
INCREASE CO2, ACID/ALTITUDE, 2,3 DPG, EXERCISE, TEMP
Term
WHAT DOES CO POISON Hb?
Definition
COMPETIITIVE INHIB OF O2, ON HB - CHERRY RED LIPS, PINKISH SKIN HUE
Term
HOW DOES CYANIDE POISON HB?
Definition
NON-COMP INHIBIT OF 02, ON HB - ALMOND BREATH
Term
WHAT IS MetHB?
Definition
HB W/FE 4+
Term
ACUTE INTERMITTENT PORPHYRIA
Definition
INCREASED PORPHYRIN, URINE DELTA-ALA, PORPHOBILINOGEN --> ABDO PAIN, NEUROPATHY, RED URINE
Term
PORPHYRIA CUTANEA TARDA
Definition
SUNLIGHT - SKIN BLISTES W/PORPHYRIN DEPOSITS, WOOD'S LAMP -- ORANGE-PINK
Term
ERYTHROCYTIC PROTOPORHYRIA
Definition
PORPHYRIA CUTANEA TARDA IN A BABY
Term
SICKLE CELL DISEASE
Definition
HOMOZYGOUS, HbS - GLU 6 - VAL -- VASO-OCCCLUSION, NECROSIS, DACTYLITIS, PAINFUL FINGERS/TOES AT 6PM, PROTECTS AGAINST MALARIA
Term
SICKLE CELL TRAIT
Definition
HETEROZYGOUS HBs - PAINLESS HEMATURIA, SICKLE WITH EXTREME HYPOXIA (CAN'T BE PILOT OR FIREMAN)
Term
WHAT IS HbC?
Definition
GLU6 - LYS - STILL CHARGED, SO NO SICKLING (ITS OUTSIDE THE CELL)
Term
WHAT IS ALPHA THALASSEMIA?
Definition
1 DELETION NORMAL
2 DELETIONS 'TRAIT' MICROCYTIC ANEMIA
3 DELETIONS HEMOLYTIC ANEMIA - HB H= B4
Term
WHAT IS BETA THALASSEMIA?
Definition
1 DELETION MINOR - INCREASED HBA2 AND HB4
2 DELETION TRAIT/INTERMIDIA/MAJOR: ONLY IF HBA2 AND HBF --> HYPOXIA AT 6MO
Term
WHAT IS COOLEY'S ANEMIA?
Definition
SEE W/BETA-THALASSEMIA MAJOR, NO HbA - EXCESS RBC PRODUCTOIN -- BABY MAKING BLOOD FROM EVERYWHERE - FRONTAL BOSSING WITH HEPATOSPLENOMEGALY n' LONG EXTREMITIES
Term
WHAT IS VIRCHOWS TRIAD
Definition
THROMBOSIS RISK FACTOR -
1/TURBULANT BLOOD FLOW, SLOW
2/HYPERCOAGULABLE, STICKY
3/VESSEL WALL DAMAGE, ESCAPES
Term
WHAT DOES ACUTE HYPOXIA CAUSE?
Definition
SHORTNESS OF BREATH
Term
WHAT DOES CHRONIC HYPOXIA CAUSE?
Definition
CLUBBING OF FINGERS/TOES
Term
INTRAVASCULAR HEMOLYSIS
Definition
RBC DESTROYED BY BLOOD VESSELS - LOW HAPTOGLOBIN (BINDS FREE FLOATING HB, ITS LOW B/C ITS ALL BOUND Up!)
Term
EXTRAVASCUALAR HEMOLYSIS
Definition
RBC DESTROYED BY SPLEEN - PROBLEM WITH RBC MEMBRANE, SPLENOMEGALY
Term
ENZYMES NEED LEAD (PB)
Definition
DELTA ALA DEHYDRASE, FERROCHELATASE
Term
WHAT DOES EDTA BIND TO?
Definition
X ^ 2+, ANYTHING FREE FLOATING WITH 2+ CHARGE (CA, MG, ETC)
Term
SMOOTH PHILTHRUM
Definition
FETAL ALCOHOL SYNDROME
Term
LONG PHILTHRUM
Definition
WILLIAMS
Term
SAUSAUGE DIGITS
Definition
PSEUDO-HYPOPARATHYROIDISM, PSORIATIC ARTHRITIS
Term
DISEASE WITH 6 FINGERS
Definition
PATAU, TRI 13
Term
DISEASE WITH 2 JOINTED THUMS
Definition
EDWARDS, 18 TRI
Term
DZ WITH PAINFUL FINGERS
Definition
SICKLE CELL DISEASE (MICROINFARCT)
Term
MICROCYTIC HYPOCHROMIC ANEMIAS?
Definition
SMALL AND LACKING HB ANEMIA - FAST Lead - Fe DEF, ANEMIA OF CHRONIC DZ, SIDEROBLASTIC ANEMIA, ALPHA AND BETA THALASSEMIA, PB POISONING
Term
IRON DEF ANEMIA
Definition
MICROCYTIC HYPOCHROMIC, INCREASED TIBC, MENSES, GI BLEED, KOILONYCHIA -- INCREASED TIBC B/C ITS LOOKING FOR FE!!!
Term
ANEMIA OF CHRONIC DZ
Definition
MICROCYTIC HYPOCHROMIC - DECRASED TIBC, (MHC/MCV - LOW TIBC B/C ITS GOT FE BUT ITS LOSING BLOOD ALL TOGETHER FROM SOMEWHERE
Term
SIDEROBLASTIC ANEMIA
Definition
MICROCYTIC HYPOCHROMIC - DECRASE IN DELTA-ALA SYNTHASE, BLOOD TRANSFUSIONS (BECAUSE HEME IS AN INHIBITOR OF ALA SYNTHASE IN THE HEME PATHWAY - SO IT GET NEGATIVE FEEDBACK N' SHUTS DOWN)
Term
ALPHA THALASSEMIA
Definition
MICROCYTIC HYPOCHROMIC, ALPHA FOR ASIANS - CHR 16 DELETION
Term
BETA THALASSEMIA
Definition
MICROCYTIC HYPOCHROMIC, B FOR BELOW MEDITERRANEANS - CH 11 POINT MUTATION
Term
PB POISONING
Definition
MICROCYTIC HYPOCHROMIC - DECREASE IN ALA DEHYDROGENASE, DECREASE FERROCHELATASE, XRAY BLUE LINE, EATING OLD PAINT CHIPS
Term
MEGALOBLASTIC ANEMIAS? ONLY 3...
Definition
1/VIT B12 DEF (TAPEWORMS, VEGAS, TYPE A GASTRITIS, PERNICIOUS ANEMIA)
2/FOLATE DEF (OLD FOOD, MICROWAVED A LOT, AND GLOSSITIS)
3/ALCOHOL (FETAL ALCOHOL SYNDROME - SMOOTH PHILTHRUM, STUFF DOESN'T GROW)
Term
INTRAVASCULAR HEMOLYTIC ANEMIAS? (ONLY 2...)(DECREASED LEVELS OF HAPTOGLOBIN)
Definition
ALL IgM**
1/ G6PD DEF - SULFA DRUGS, MOTH BALLS, FAVA BEANS, SUDDEN DROP IN Hb
2/ COLD AUTOIMMMUNE - MONONUCLEOSIS, MYCOPLASM INFECTIONS, RBC AGGLUTINNATION
Term
EXTRAVASCULAR HEMOLYTIC ANEMIAS (NAME 4...)?
Definition
ALL OF EM IgG**
1/SPHEROCYTOSIS (DEFECTIVE SPHERIN OR ANKYRIN, + OSMOTIC FRAGILITY TEST)
2/WARM AUTOIMMUNE (ANTI-RH AB, DAPSONE, PTU, ANTIMALRIALS****, SULFA DRUGS
3/PARAXYSMAL COLD AUTOIMMUNE (BLEEDS AFTER COLD EXPOSURE, DONATH LANDSTEINER AB)
4/SICKLE CELL ANEMIA (CREW HAIRCUT XRAY , AVASCULAR NECROSIS OF FEMUR AND SHORT FINGERS)
Term
PRODUCTION ANEMIA'S - TWO TO THINK ABOUT...
Definition
DIAMOND BLACKFAN (NO RBC'S AND 2 JOINTED THUMBS)
APLASTIC ANEMIA (PANCYTOPENIA, AUTOIMMUNE, BENZENE, AZT, CAM, RADIATION
Term
basophilic stippling?
Definition
LOTS OF IMMATURE CELLS, INCREASED mRNA, PB POISONING
Term
BITE CELLS
Definition
UNSTABLE HB INCLUSIONS G6PD DZ
Term
BURR CELLS
Definition
PYRUVATE KINASE DEF, LIVER DZ, POST SPLEENECTOMY
Term
CABOT RINGS
Definition
VIT B12 DEF, PB POISONING
Term
DOEHLE BODY
Definition
PMN LEUKOCYTOSIS (INFECTION, STERIODS, TUMOR)
Term
DREPANOCYTE
Definition
SICKE CELL ANEMIA
Term
HELMET CELL
Definition
FRAGMENTED RBC, HEMOLYSIS; DIC, HUS, TTP AND VASCULITIS (ALSO HAS BURR CELLS)
Term
HEINZ BODIES
Definition
HP PRECIPITATES AND STICKS TO CELL MEMBRANE - G6PD DEF
Term
HOWELL-JOLLY BODIES
Definition
SPLEEN OR BONE MARROW SHOULD HAVE REMOVED NUCLEI FRAGMENTS (HEMOLYTIC ANEMIA, SLEEN TRAUMA, CANCER
Term
PAPPENHEIMER BODY
Definition
FE PPT INSIDE CELL (SIDEROBLASTIC ANEMIA
Term
PENCIL CELLS
Definition
CIGAR CELLS - CELL IN FE IRON DEF
Term
ROULEUX FORMATION
Definition
MULTIPLE MYELOMA
Term
SCHISTOCYTE
Definition
BROKEN RBC, DIC, ARTIFICAL HEART VALVES TEARING UP RBC
Term
SIDEROBLAST
Definition
MACROPHAGES PREG WITH FE (GENETIC OR MULTIPLE TRANSFUSIONS
Term
SPHEROCYTE
Definition
OLD RBC
Term
SPUR CELLS - ACANTHOCYTE
Definition
LIPID BILAYER DZ
Term
STOMATOCYTE
Definition
LIVER DZ
Term
TARGET CELL - CODOCYTES
Definition
*****THALASSEMIAS (EASTERN/MEDITTARIAN HIST OF DECENT) OR FE DEF DZ
Term
TEAR DROP CELL - DACROCYTE
Definition
RBC'S ARE BEING SQUEEZED OUT OF BONE MARROW, HEMOLYTIC ANEMIA, BONE MARROW CANCER
Term
CLOTTING CASCADE
Definition
STOP BLEEDING
Term
PLATELET PROBLEMS
Definition
BLEEDING IN SKIN N' MUCOSA
Term
CLOTTING PROBLEMS
Definition
BLEEDING IN TO CAVITIES
Term
INCREASED PTT AND BLEEDING TIME
Definition
VON WILLIEBRAND DISEASE AND LUPUS**
Term
BERNARD-SOULIER
Definition
BABY WITH BLEEDING FROM SKIN N' MUCOSA - BIG PLATELETS FLOATING AROUND B/C IT NEVER ADHESIONED TO ENDOTHELIUM (LOW Gp1B)
Term
GLANZMANN'S
Definition
BABY BLEEDING FROM SKIN N' MUCOSA (LOW Gp2/3) -- CAN BE MIMIC'D BY DRUG ABCIXIMAB B/C MOA IS BLOCK THIS! - USED DURING ANGIOPLASTY STENT OR NO STENT
Term
FACTOR 13 DEF PRESENT?
Definition
BABY UMBLICIAL STUMP BLEEDING (FIRST TIME ANYONE BLEEDS
Term
FACTOR 5 LEIDEN?
Definition
MUTATION OF FACTOR 5 LEAVES PROTEIN C AND S FLOATING AROUND UNAFFECTED. LEADS TO HEREDITARY HYPERCOAGULABLE STATE. NORMALLY PROTEIN C n' S BREAK DOWN 5
Term
HOW DOES vWF DISEASE PRESENT?
Definition
HEAVY MENSTRUAL BLEEDING, AUTOSOMAL DISEASE AND PT WILL THINK ITS NORMAL B/C MOM WILL TELL THEM YEAH I BLEED THAT MUCH TOO WHEN I WAS YOUNGER
Term
vWF DISEASE TYPES?
Definition
1/TYPE 1 AD, DECREASED PROD OF vWF
2/TYPE 2 AD, vWF AND *****RISTOCETIN AGGREGATION TEST POSITIVE - KEYWORD RISTOCETIN TEST***
3/ TYPE 3, AR - NO VWF - OH FUCK
Term
WHAT IS HEMOPHILIA A?
Definition
DEFECTIVE FACTOR 8! - ITS AROUND AND NUMBER IS NOT AFFECTED, THE ACTIVITY IS <40% (REMEMBER ACTIVITY AFFECTED)! -- BLEED INTO CAVITIES, HEAD N' ABDOMEN (CLASSIC DENTIST VISIT, TOOTH WON'T STOP BLEEDING AFTER EXTRACTION)
Term
HEMOPHILIA B?
Definition
FACTOR 9 MISSING!! (UNLIKE HEM A, WHERE ACTIVITY OF 8 IS DECREASED, HERE IN HEM B THE FACTOR, 9, IS MISSING!!) - BLEED INTO JOINTS***
Term
DISEASES THAT HAVE LOW LAP SCORE?
Definition
CML AND PNH
Term
DISEASES THAT HAVE HIGH LAP SCORE?
Definition
LEUKEMOID REACTION - SERIOUS STRESS DEMARGINATION OF WBC
Term
DIFF BETWEEN ACUTE N' CHRONIC LEUKEMIA?
Definition
ACUTE - STARTED IN BONE MARROW, SQUEEZES OUT RBC
CHRONIC - STARTED IN PERIPHERY, NOT CONSTRAINED - WILL EXPAND
Term
DIFF BETWEEN MYELOID AND LYMPHOID LEUKEMIAS?
Definition
MYELOID - INCREASED RBC, WBC, PLATELETS, MP, (DECREASED LYMPHOID CELLS), BONE MARROW BIOPSY
LYMPHOMA; INCREASED NK, T, B CELLS, (DECREASED MYELOID CELLS) - DO LYMPH NODE BIOSPY
Term
DEFINE ALL?
Definition
ACUTE, SO BONE MARROW. LYMPHOID, SO DECREASED MYELOID CELLS (NK, T, N' B CELLS ARE UP) -- <15 Y/O PT, BONE PAIN, PAS STAIN POSITIVE, and TdT POSITIVE
Term
DEFINE AML?
Definition
ACUTE, SO BONE MARROW. MYELOID, SO INCREASED RBC, WBC, N' MP. -- 15-30YO MALE, SUDAN STAIN, AUER RODS (PEROXIDASE +), M3, VIT A, t15;17
Term
DEFINE CML?
Definition
CHRONIC, PERIPHERY STARTING AND MYELOID CELL ARE UP. -- 30-50yo WOMAN t9;22 PHILLY CHR, DECREASED LAP SCORE**** BCL-ABL GENE
Term
DEFINE CLL?
Definition
>60yo MALES, LYMPHADENOPATHY, SOCCER BALL NUCLI, SMUDGE CELLS
Term
WHAT IS HODGKINS LYMPHOMA?
Definition
REED STERNBERG CELLS, EBV, CD30 MARKER FOR CELLS
Term
WHAT IS NON-HODGKINS B CELL LYMPHOMA?
Definition
FOLLICULAR 14;18T, BCL-2 (ADULT)
BURKITTS 8;14T, C-MYC, STARRY SKY MP (KIDS) (AFRICAN KID - JAW, AMERICAN - ABDO MASS)
Term
WHAT IS NON-HODGKINS T CELL LYMPHOMA?
Definition
MYCOSIS FUNGOIDES; TOTAL BODY RASH
SEZARY SYNDROME; CEREBREFORM CELLS
Term
WHAT IS POLYCYTHEMIA RUBRA VERA?
Definition
HCT >60%, DECREASED EPO****, BUDD CHIARI, PLETHORA "PRURITIS AFTER BATHING"
Term
WHAT IS ESSENTIAL THROMBOCYTHEMIA?
Definition
VERY HIGH PLATELET COUNT (-EMIA), STAINABLE FE, DECREASED C-MPL
Term
WHAT IS MYELOFIBROSIS?
Definition
MEGAKARYOCYTES, FIBROTIC MARROW - TEAR DROP CELL, EXTRAMEDULLARY HEMATOPOIESIS (SPLEEN MAKING BLOOD)
Term
WHAT ARE PLASMA NEOPLASMS?
Definition
LOTS OF AB PRODUCTION
Term
WHAT IS WALDENSTORM MACROGLOBULINEMIA?
Definition
IgM AND HYPERVISCOUS (M FOR MACRO, N' m UPSIDE DOWN IS WALDENSTORM)
Term
WHAT IS MONOCLONAL GAMMOPATHY OF UNDERTERMINED SIGNIFICANCE?
Definition
OLD PERSON WITH GAMMA SPIKE*** GAMMA SPIKE ALSO MULTIPLE MYELOMA
Term
WHAT IS MULTIPLE MYELOMA?
Definition
SERUM M PROTEIN, IgG, URINE BENCE-JONES PROTEIN, ROULEUX, PUNCHED OUT LESIONS, KAPPA LIGHT CHAINS
Term
HEAVY CHAIN DISEASE?
Definition
INCREASED IgA
Term
HISTOCYTOSIS X?
Definition
KID WITH ECZEMA, SKULL LESIONS, DIABETES INSIPIDUS, AND EXOPHTHAMOS
Term
COOBS TEST TELL US?
Definition
AB INVOLVED
Term
DIRECT COOBS TEST?
Definition
ON SURFACE OF CELL - HEMOLYTIC ANEMIA
Term
INDIRECT COOBS TEST?
Definition
IN SERUM
Term
WHAT IS TYPE N' CROSS BLOOD MATCH?
Definition
PT BLOOD MATCH, READY FOR US, GOING TO SURGERY
Term
WHAT IS TYPE N' MATCH BLOOD MATCH?
Definition
TYPE THE BLOOD TYPE N' WAIT, JUST CHILLING ON THE SIDE
Term
WHAT IS FORWARD TYPING?
Definition
USES AB TO DETECT AG, "fabULOUS"
Term
WHAT IS BACKWARD TYPING?
Definition
USES AG TO FIND AG
Term
WHAT DOES BLOOD A TELL YOU?
Definition
ANTIGEN FOR A, AB FOR TYPE B
Term
WHAT DOES TYPE O TELL YOU?
Definition
NO ANTIGENS, UNIVERSAL DONOR
Term
WHAT DOES TYPE AB TELL YOU?
Definition
HAVE BOTH ANTIGENS, SO RECOGNIZED BY BOTH BLOOD TYPES, SAVE TO BE UNIVERSAL RECIPIENT IN BLOOD EXCHANGE
Term
WHAT DOES Rh + TELL YOU?
Definition
HAS D ANTIGEN
Term
WHAT DOES Rh - TELL YOU?
Definition
DOES NOT HAVE D ANTIGEN
Term
WHAT IS HEMOLYTIC DISEASE OF NEWBORN
Definition
Rh - MOM'S PLACENTA TEARS, 100CC OF BABY BLOOD SEES MOM/PRODUCES AB, ATTACKS FETUS!!!
Term
WHAT IS RHOGAM?
Definition
SHOT GIVEN TO HELP WITH PREVENT HEMOLYTIC DISEASE OF NEWBORN - ANTI-D IgG
Term
WHEN TO GIVE RHOGAM?
Definition
AT 28WKS FOR FIRST DOSE, THEN 72HRS POST DELIVERY (Rh+BABY)
Term
MOST COMMON TRANSPLANT?
Definition
BLOOD
Term
SYNGENIC TRANSPLANT?
Definition
TWIN TO TWIN
Term
ALLOGRAFT?
Definition
HUMAN TO HUMAN
Term
XENOGRAFT?
Definition
PIG VALVE...ENOUGH SAID
Term
HYPERACUTE REJECTION
Definition
WITHIN HOURS, PREFORMED ANTIBODIES, ORGAN SWELLING - TAKE IT BACK OUT
Term
ACUTE REJECTION
Definition
THE ONLY ONE WE'LL KEEP IN THE PT WITH TREATMENT - 4 DAYS TO YEARS LATER - T CELLS AND MACROPHAGES - CELL MEDIATED IMMUNITY GOT A WHIFF OF IT
Term
CHRONIC REJECTION
Definition
GOTTA TAKE IT OUT SOONER OR LATER, FIBROBLAST, YOU'LL SEE CALCIFICATIONS
Term
WHAT IS GRAFT VS. HOST?
Definition
THAT ONE LONE GUNMAN OF A LEUKOCYTE REMAINING FROM THE DONOR JUST GOES OUT LIKE RAMBO LOOKING FOR REVENGE!! - BONE MARROW TRANSPLANT REJECTION, Tk and MACROPHAGES
Term
WHAT IS IMMUNOPRIVLEGED SITE?
Definition
WELL NOT ACTUALLY A GOOD THING IN DISEASE AFFECTED STATE, BUT GOOD FOR DONATE/TRANSPLANTS - NO LYMPHATIC FLOW - NO ANTIGENS SO EASY TRANSPLANT (BRAIN, CORNEA, THYMUS, TESTES - NOTE HEART NOT LISTED NEED >60 HLA TYPING MATCH, ITS VERY UN-IMMUNOPRIVLEGED)
Term
WHAT IS INR?
Definition
MEASURED PT (DIVIDED BY) / CONTROL PT
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