Term
| What is forward ABO testing? |
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Definition
| Looking for antigen (check RBCs w/ reagent antisera) |
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Term
| What is reverse ABO testing? |
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Definition
| Looking for Ab (check serum/plasma w/ reagent A1 and B cells) |
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Term
| A person w/ type O blood has what type of antigens? Ab? |
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Definition
| Antigen: neither, Ab: anti-A, -B, and -AB |
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Term
| A person w/ type A blood has what type of antigens on their RBCs? Ab in serum? |
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Definition
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Term
| A person w/ type B blood has what type of antigens? Ab? |
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Definition
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Term
| A person w/ type AB blood has what type of antigens? Ab? |
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Definition
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Term
| What condition of the fetus can occur when the mother has Rh (-)? |
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Definition
| Hemolytic Disease of the Fetus and Newborn (HDFN) |
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Term
| Rhesus factor refers to the presence of what? |
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Definition
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Term
| What are the Rh antibodies? Can they pass the placental barrier? |
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Definition
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Term
| What is a type and screen? Type of Cross? |
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Definition
| ABO/RH/Ab screen (pretransfusion test). Type and screen plus crossmatching. |
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Term
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Definition
| Immediate spin (IS) or AHG |
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Term
| Describe the pathogenesis of HDFN. |
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Definition
| Occurs when a mother is RhD (-) and sensitization to Rh D antigens (by feto-maternal transfusion during pregnancy) can result in the production of maternal IgG anti-RhD antibodies. This becomes a problem in subsequent pregnancies when the baby is Rh-D (+) |
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Term
| What is given to an Rh-D (-) mother to prevent sensitization of the immune system to Rh D antigens? |
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Definition
| IM solution of IgG anti-D (anti-RhD) Ab destroy fetal Rh D (+) RBCs that have passed from the fetal circulation to the maternal circulation (RhoGAM) |
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Term
| What are some s/sx of HDNF? |
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Definition
| Hepatosplenomegaly, jaundice, anemia |
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