Term
| What is the total volume of blood in the average adult? |
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Definition
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Term
| Approximately what percentage of total volume of blood consist of Red Blood Cells? |
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Definition
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Term
| What's the difference in Serum and Plasma? |
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Definition
| Plasma contains coagulation clotting factors, serum does not. |
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Term
| What is a dynamic process of cell production that maintains and regulates the cellular population of leukocytes, erythrocytes, and platelets? |
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Definition
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Term
| What is the precursor to all cell lines? |
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Definition
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Term
| What gives rise to red blood cells? |
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Definition
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Term
| What gives rise to platelets? |
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Definition
| Megakaryocytic blast cells |
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Term
| What gives rise to neutrophiles, eosinophils, and basophils? |
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Definition
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Term
| What gives rise to monocytes? |
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Definition
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Term
| Where is Erythrocytes primarily produced in? |
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Definition
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Term
| How long does the RBC maturation sequence take? |
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Definition
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Term
| What is the generation of red blood cells known as? |
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Definition
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Term
| What happens to the nucleus of the RBC as it matures? |
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Definition
| It decreases in size and eventually extruded from the cell |
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Term
| What is the first phase of erythrocyte development? |
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Definition
| Pronormoblast (Rubriblast) |
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Term
| What cell follows the Pronormoblast in the Erythroid Maturation Order? |
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Definition
| Basophilic Normoblast (Prorubricyte) |
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Term
| What cell follows the Basophilic Normoblast in the Erythroid Maturation Order? |
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Definition
| Polychromatic Normoblast (Rubricyte) |
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Term
| What cell follows the Polychromcatic Normoblast in the Erythroid Maturation Order? |
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Definition
| Orthochromatic Normoblast (Metarubricyte) |
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Term
| What cell follows the Orthochromatic Normoblast in the Erythroid Maturation Order? |
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Definition
| Polychromatic Erythrocyte (Reticulocyte) |
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Term
| What cell follows the Polychromatic Erythrocyte in the Erythroid Maturation Order? |
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Definition
| Erythrocyte (Red Blood Cell) |
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Term
| What is a term used to describe a cell of normal color? |
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Definition
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Term
| What is a term to describe pale RBCs that have an increased central pallor as a result of decreased hemoglobin and iron production? |
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Definition
| Hypochromic (Hypochromasia) |
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Term
| What is a term that refers to RBCs that show a faint blue color after staining with Wright's stain? |
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Definition
| Polychromic (Polychromasia) |
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Term
| What is a term used to describe variation in the cell size? |
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Definition
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Term
| What is a term used to describe large RBCs? |
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Definition
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Term
| What is a term to describe small RBCs? |
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Definition
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Term
| What is a term used to indicate an increased variation in the shape of RBCs? |
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Definition
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Term
| What is a pattern of stacked RBCs that stick together (stacked coin appearance)? |
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Definition
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Term
| What is the clumping of cells? |
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Definition
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Term
What is the formula to calculate the corrected WBC count on a differential with the following:
9.0 X 10^9 WBCs/L, 8 NBCs |
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Definition
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Term
| What is the cytoplasmic portions that circulate within the blood that are an essential part of the blood-clotting mechanism? |
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Definition
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Term
| What is the normal total PLT count? |
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Definition
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Term
| What is the normal range for a platelet estimate reported as "Adequate"? |
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Definition
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Term
| What is the the Thrombocyte Maturation Sequence? |
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Definition
| Megakaryoblast, Promegakaryocyte, Megakaryocyte, Platelet |
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Term
| What is the stain of choice for a Differential Cell count? |
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Definition
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Term
| What is the measure of the regeneration or production of RBCs? |
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Definition
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Term
| What is the adult reference range for reticulocytes? |
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Definition
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Term
| What is a term to describe an elevated reticulocyte count? |
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Definition
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Term
| What stain is used for counting reticulocytes? |
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Definition
| Supravital New Methylene Blue Stain |
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Term
| If you had 30 reticulocytes counted in 5 fields of 200 RBCs, what is the percent Reticulocyte? What about 45 retics? |
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Definition
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Term
| What is a conventional definition of a decrease in RBCs, HGB and HCT below established normal values for healthy persons of the same age, gender, and race and under similar conditions |
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Definition
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Term
| What is the MCV for microcytic cells? |
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Definition
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Term
| What is the MCV for Macrocytic cells? |
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Definition
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Term
| What is the MCV for normocytic cells? |
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Definition
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Term
| What is the Screening test for PNH? |
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Definition
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Term
| What is the confimatory test for PNH? |
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Definition
| Ham's Acidified Serum Test |
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Term
| What presents as a Normocytic/Normochromic Anemia but with a severely lowered Hemoglobin and Hematocrit? |
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Definition
| Anemia caused by acute blood loss |
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Term
| What anemia occors over an extended period of time, results in Iron Deficiency Anemia, associated with disorders of the GI Tract and heavy menstrual flow? |
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Definition
| Anemia caused by chronic blood loss |
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Term
| What anemia occors over an extended period of time, results in Iron Deficiency Anemia, associated with disorders of the GI Tract and heavy menstrual flow? |
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Definition
| Anemia caused by chronic blood loss |
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Term
| What develops when the intake of iron is inadequate and when the need for iron increases or when chronic loss of Hemoglobin is present? |
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Definition
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Term
| What are Genetic Disorders of structure and/or synthesis of one or more of the globin chains - results in abnormal structure? |
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Definition
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Term
| What are Genetic Disorders of structure and/or synthesis of one or more of the globin chains - results in abnormal structure? |
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Definition
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Term
| What is a condition in which Homozygous Hgb S (Hgb SS) or Hemoglobin S is expressed due to a substitution of one amino acid in the globin chain? |
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Definition
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Term
| What is Heterozygous Hgb S and Hgb A chains? |
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Definition
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Term
| What is the most common Double Heterozygous Syndrome? |
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Definition
| Sickle Cell-Hgb C disease (Hgb SC) |
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Term
| What is a defective globin synthesis results in defective Hemoglobin production and damage to the RBCs? |
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Definition
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Term
| What results when one of the two genes that produce the Beta globin chains is defective? |
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Definition
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Term
| What is characterized by a Severe Anemia detected in early childhood as the gamma chain to beta chain switch takes place? |
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Definition
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Term
| What Anemia occurs when iron accumulates in the perinuclear mitochondria of normoblasts and reveal the iron as blue deposits surrounding the nucleus? |
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Definition
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Term
| What anemia occurs from excess accumulation of iron from acquired or hereditary conditions in which the body's rate of iron acquisition exceeds the rate of loss? |
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Definition
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Term
| What heavy metal anemia are children at special risk due to affects on the Central Nervous System and impaired mental development? |
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Definition
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Term
| What anemia is associated with hypersegmented neutrophils? |
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Definition
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Term
| What anemia results from a poor diet lacking in green leafy vegetables, dried beans, liver, beef and oranges? |
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Definition
| Megaloblastic Anemia due to Folate Deficiency |
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Term
| What Anemia is seen with strict vegatarians? |
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Definition
| Megaloblastic Anemia's due to Vitamin B12 Deficiency |
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Term
| What anemia is associated with Pure Red Cell Aplasia and diamond-blackfan anemia? |
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Definition
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Term
| This anemia hemolyzes RBCs at cold temperatures 10-30C caused by the IgM Antibody |
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Definition
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