Term
|
Definition
| MCV low, Hb low, Hc low, pica is present |
|
|
Term
|
Definition
| MCV low, reticulocyte count high, skeletal abnormalities |
|
|
Term
|
Definition
| MCV low, mild anemia, abnormal hemoglobin electrophoresis, asymptomatic |
|
|
Term
|
Definition
| MCV variable, autosplenectomy, reversible aggregation of erythrocytes |
|
|
Term
| Megaloblastic Anemia (folate deficiency) |
|
Definition
| Hypersegmented neutrophils, MCV high, corrected by administration of folate |
|
|
Term
|
Definition
| hypersegmented neutrophils, MCV high, atrophic gastritis, CNS effects |
|
|
Term
| Autoimmune hemolytic anemia warm type |
|
Definition
| organomegaly, abrupt onset hemolysis, jaundice |
|
|
Term
| Autoimmune hemolytic anemia cold type |
|
Definition
| insidious onset hemolysis, no organomegaly, more common in women |
|
|
Term
|
Definition
| spherical RBCs, aplastic crisis triggered by parvovirus, splenectomy corrects anemia |
|
|
Term
|
Definition
| schistocytes, Heinz bodies, hemolysis in response to oxidative stress |
|
|
Term
| Immune Thrombocytopenic purpura |
|
Definition
| presents with petechiae in children, often get spontaneous remission |
|
|
Term
| Thrombotic thrombocytopenic purpura |
|
Definition
| thrombocytopenia, microangiopathic hemolytic anemia, Fever, neurological abnormalities, renal failure |
|
|
Term
| Hemolytic uremic syndrome |
|
Definition
| thrombocytopenia, microangiopathic hemolytic anemia, Fever, renal failure |
|
|
Term
| Disseminated Intravascular coagulation |
|
Definition
| D dimer elevated, PT and PTT elevated, shistocytes present |
|
|
Term
| Heparin induced thrombocytopenia |
|
Definition
| thrombocytopenia, detection of HIT antibodies |
|
|
Term
|
Definition
| PT normal, PTT elevated, mixing study shows correction of PTT |
|
|
Term
|
Definition
| PT and PTT normal, clot stability assay shows instable clot |
|
|
Term
|
Definition
| Thrombin time elevated, PTT elevated, reptilase time prolonged |
|
|
Term
|
Definition
| Thrombin time elevated, PTT elevated, reptilase time normal |
|
|
Term
| von Willebrand Disease types 1, 2A, 2M |
|
Definition
| reduced ristocetin cofactor activity, no agglutination in RIPA assay |
|
|
Term
| von Willebrand Disease type 2B |
|
Definition
| reduced ristocetin cofactor activity, agglutination in RIPA assay |
|
|
Term
|
Definition
| fibrinogen cofactor in platelet assay causes agglutination, ristocetin-vWF cofactor in platelet assay causes no agglutination |
|
|
Term
| Glanzmann's thrombasthenia |
|
Definition
| fibrinogen cofactor in platelet assay causes no agglutination, ristocetin-vWF cofactor in platelet assay causes agglutination |
|
|
Term
| Vitamin K antagonist present |
|
Definition
| PT elevated, INR elevated |
|
|
Term
|
Definition
| activated protein C resistance |
|
|
Term
|
Definition
| 130% normal levels of prothrombin |
|
|
Term
|
Definition
| homocysteinemia, venous and arterial thrombotic events |
|
|
