Term
| furosemide, bumetanide, torsemide: class? |
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Definition
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Term
| hydrochlorathiazide, chlorathalidone, metolazone: class? |
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Definition
|
|
Term
| enalapril, captopril: class? |
|
Definition
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Term
|
Definition
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Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| spironolactone, eplerenone: class? |
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Definition
| aldosterone inhibitors = K+ sparing diuretics |
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Term
|
Definition
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Term
| MOA of furosemide vs. HCTZ |
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Definition
| furosemide inhibits Cl- reabsorption; HCTZ inhibits Na reabsorption |
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Term
|
Definition
| azotemia, hypokalemic metabolic acidosis, skin rash, ototoxicity |
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Term
|
Definition
| azotemia, hypokalemic metabolic acidosis, skin rash, thrombocytopenia, neutropenia |
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Term
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Definition
| inhibits ventricular remodeling, reverses endothelial dysfunction, decreases afterload by inhibiting conversion of angiotensin I to angiotensin II |
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Term
|
Definition
| cough, angioedema, hypotension, renal insufficiency, rash, fetopathic |
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Term
|
Definition
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Term
|
Definition
| acute renal failure, hyperkalemia |
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Term
| AE: self limiting SLE-like syndrome |
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Definition
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Term
|
Definition
| hyperkalemia, gynecomastia |
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Term
| MOA: inhibits AV node conduction by centrally increasing vagal tone |
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Definition
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|
Term
| proven to reduce mortality |
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Definition
| ACEi, aldosterone inhibitor, ARB, aspirin, beta blockers |
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|
Term
| symptomatic relief only; no reduction in mortality |
|
Definition
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|
Term
|
Definition
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|
Term
| AE: thrombocytopenia, neutropenia |
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Definition
| HCTZ, chlorathalidone, metolazone |
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|
Term
| indicated for CHF class III, particular CHF+shock |
|
Definition
| inotropics: digoxin, dobutamine |
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|
Term
| MOA: inhibits ventricular remodeling |
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Definition
| ACEi, beta blockers, aldosterone inhibitors |
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Term
| always indicated in pts with <40% EF |
|
Definition
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|
Term
| what defines each class in the NYHA classification? |
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Definition
| I: CHF with exertion; II: CHF with normal activity; III: CHF with minimal exertion; IV: CHF at rest |
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Term
| tx for acute pulmonary edema |
|
Definition
| LMNOP: lasix, morphine, nitrates, oxygen, [upright] position |
|
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Term
| what compensatory mechanism is beneficial in the long-run? |
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Definition
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|
Term
| hypertrophic cardiomyopathy causes [systolic/diastolic] heart failure |
|
Definition
|
|
Term
| restrictive cardiomyopathy causes [systolic/diastolic] heart failure |
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Definition
|
|
Term
| pericardial diseases (pericarditis, pericardial effusion, constrictive pericarditis) causes [systolic/diastolic] heart failure |
|
Definition
|
|
Term
| chronic anemia causes [systolic/diastolic] heart failure |
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Definition
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|
Term
| doxorubicin causes [systolic/diastolic] heart failure |
|
Definition
|
|
Term
| what are the 3 determinants of stroke volume? |
|
Definition
| contractility, preload, and afterload |
|
|
Term
| Takotsubo's cardiomyopathy is caused by... |
|
Definition
| elevated levels of catecholamines and other stress-induced hormones; aka. "broken heart syndrome" |
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|
Term
| nitrates act preferentially on ___ |
|
Definition
| veins and large coronary aa. |
|
|
Term
| MOA of clopidogrel and its indication |
|
Definition
| inhibits ADP-activation of platelets; indicated for arterial clots |
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|
Term
| abiciximab: class? indication? |
|
Definition
| gpIIb/IIIa inhibitor; indicated for ACS and non-Q wave MI |
|
|
Term
| enoxaparin: class? indication? |
|
Definition
| LMWH = anticoagulant; indicated for venous clots |
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|
Term
|
Definition
| warfarin as a large loading dose |
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|
Term
|
Definition
|
|
Term
| nifedipine: class? effect on heart rate? |
|
Definition
| Ca channel blocker; increases heart rate as a reflex to vasodilation |
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