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heart drugs I- Todd
angina pec./anticoag/etc.
53
Health Care
Undergraduate 2
03/15/2007

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Cards

Term
What are the two categories of arrhythmias?
Definition
Supraventricular and Ventricular
Term
Digoxin may cause which type of dysrhythmia?
Definition
Ventricular dysrhythmia
Term
Torsades de Pointes is associated with which type of dysrhythmia?
Definition
Ventricular
Term
Quinidine and Procainamide are under what class of antidysrhythmics?
Definition
Class Ia
Term
What are the 3 ADRs for Quinidine?
Definition
1. Proarrhythmia
2. Diarrhea
3. Cinchonism (tinnitus, nausea, headache, vertigo)
Term
Which class of sodium channel blockers prolongs the QT interval?
Definition
Ia
Term
Which drug is associated with causing hypotension and a Systemic Lupus Erythematosus-like syndrome?
Definition
Procainamide
Term
Which Class I drug has side effects of hypotension and heart failure?
Definition
Disopyramide
Term
How are class Ib drugs different than Ia in regards to repolarization?
Definition
Class Ib ACCELERATES repolarization whereas Ia delays repolarization.
Term
What is the major side effect of Lidocaine?
Definition
CNS problems
Term
What is the major side effect of class Ic Flecainide? And what population is especially at risk?
Definition
Death; People with structural heart abnormalities
Term
What are the 4 adverse effects of Class II Beta Blockers?
Definition
1. Sluggishness
2. Heart block
3. Heart failure
4. Bronchospasms
Term
What class of antidysrhythmic drugs is Amiodarone? And what are it's 6 side effects?
Definition
Class III- K channel blockers
1. lung toxicity
2. heart toxicity
3. skin (gray)
4. eyes
5. liver
6. thyroid
Term
What drug do you especially not want to combine with Amiodarone?
Definition
Warfarin
Term
What are the drugs that block the AV node?
Definition
Verapamil and Diltiazem
Term
Which Class III drug is also a beta blocker?
Definition
Sotalol
Term
What do you need to monitor when pts are taking dofetilide? And if it is low what are they at risk for?
Definition
Monitor Mg and K; If low, increase risk for Torsades
Term
Which class III drug is used for drug induced cardioversion (procedure where an electrical shock is delivered to the heart to convert an abnormal heart rhythm back to a normal rhythm)?
Definition
Ibutilide
Term
What are 5 Adverse effects of Verapamil and Diltiazem?
Definition
1. Heart block
2. Hypotension
3. Heart failure
4. GERD
5. Constipation
Term
What is the major adverse effect of Adenosine?
Definition
Patients will FLAT LINE for a few seconds.
Term
What is the first symptom of an adverse rxn to Digoxin and what are the other two?
Definition
Nausea;
1. Bradycardia
2. Arrhythmia
Term
Tx for chronic stable angina.
Definition
decrease oxygen demand
Term
What are your Drugs of Choice for chronic stable angina?
Definition
1. Nitrates
2. Beta blockers
3. Calcium channel blockers
Term
What is the pathophysiology of variant angina?
Definition
Spasm that occurs at any time.
Term
Beta blockers are not indicated for which type of angina?
Definition
Variant
Term
What are your drugs of choice for Variant angina?
Definition
1. Nitrates
2. Calcium Channel
Term
What is the pathophysiology of unstable angina?
Definition
vasospasm, platelet aggregation, thrombi/emboli
Term
What are your drugs of choice for unstable angina in order of use and what is the drug used after these to help maintain structure of the heart?
Definition
1. (MONA) Morphine, Oxygen, Nitrates, ASA
2. ACE Inhibitor
Term
What is MOA of Nitrates?
Definition
Vasodilation
Term
Which type of angina do you want to pay particularly close attention to the adverse rxn of Nitrates and what is this rxn?
Definition
Unstable angina; Hypotension
Term
What are the 3 adverse effects of Nitrates?
Definition
1. Headache
2. Hypotension
3. Tachycardia
Term
Name a drug interaction to be careful with when using Nitrates?
Definition
Phosphodiesterase 5 Inhibitors (Viagra, Cialis)
Term
What is the MOA of beta blockers?
Definition
1. Slow AV node
2. Decrease Contractility
Term
Name 4 Adverse effects of Beta blockers?
Definition
1. Heart failure
2. Asthma/COPD
3. Depression
4. Diabetes
Term
CCH's are not used in which type of angina?
Definition
Unstable
Term
Name the MOA of CCBs.
Definition
Reduction of afterload and some block AV node
Term
Name 5 side effects of CCBs.
Definition
1. Tachycardia
2. Bradycardia
3. Constipation
4. Edema
5. GERD
Term
What is the overall therapy for Angina?
Definition
1. Antiplatelet meds.
2. Cholesterol lowering meds
3. Angiotensin-converting enzyme inhibitors
Term
List 5 ways to decrease chances of Angina.
Definition
1. Lower cholesterol
2. lose weight
3. normal blood pressure
4. no diabetes
5. exercise
Term
Which route do you not want to give heparin?
Definition
IM
Term
What is heparin used for?
Definition
prevention of clots or prevent clot from growing
Term
What are 2 Adverse effects of heparin?
Definition
1. bleeding
2. HIT (Heparin Induced Thrombocytopenia)
Term
What do you want to monitor when patient is on heparin?
Definition
1. apTT (activated partial thromboplastin time)
2. platelets
Term
What do you especially need to monitor for patients on LMWH?
Definition
Renal function
Term
Used in DVT and PE prevention.
Definition
Fondaparinux
Term
True or false. Fondaparinux and Direct Thrombin Inhibitors do not cause HIT.
Definition
True
Term
What are the 2 uses for Direct Thrombin Inhibitors?
Definition
1. HIT
2. ACS (Acute Coronary Syndrome)
Term
Adverse effect of Warfarin
Definition
Bleeding
Term
What is the normal INR (international normalization ratio) range to monitor for patients taking warfarin?
Definition
1
Term
What is the prevention/tx range to monitor for patients taking warfarin?
Definition
2-3
Term
Name one ADP receptor antagonist
Definition
Clopidogrel
Term
Name the only type of med that dissolves clots.
Definition
Thrombolytic meds
Term
Name 5 contraindications for Thrombolytic meds.
Definition
1. INTRACRANIAL HEMORRHAGE
2. Stroke
3. Intracranial neoplasm
4. Internal bleeding
5. Aortic dissection
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