Term
|
Definition
Weight Gain
Cardiac/Seizure risk
Alpha Blockage (Hypotenssion, Tachy HR)
Anticholinergic effects
Antihistaminic effects (sedation, ataxia)
Sexual Disfunction
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|
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Term
|
Definition
Serotonin Syndrome
Anticholinertic effects,
decreased sexual ability
drowsiness
weight gain
restlessness
tiredness and weakness
insomnia |
|
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Term
|
Definition
GI complaints
Restlessness
Aggitation
Sexual Disfunction
Weight Loss
Decreased appitite
Seritonin syndrom in combined with MAOI
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|
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Term
|
Definition
TCA
Drug interactions:
Alcohol - CNS dep.
Cogentin - Inc. anticholinergic effects
Hypogycemics- low FSBS
Levothyroxine - CNS aggitation, Tachicardia
Lithium - inc. R/F seizures |
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Term
|
Definition
TCA
Drug interactions:
Alcohol - CNS dep.
Cogentin - Inc. anticholinergic effects
Hypogycemics- low FSBS
Levothyroxine - CNS aggitation, Tachicardia
Lithium - inc. R/F seizures |
|
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Term
|
Definition
TCA
Drug interactions:
Alcohol - CNS dep.
Cogentin - Inc. anticholinergic effects
Hypogycemics- low FSBS
Levothyroxine - CNS aggitation, Tachicardia
Lithium - inc. R/F seizures |
|
|
Term
|
Definition
TCA
Drug interactions:
Alcohol - CNS dep.
Cogentin - Inc. anticholinergic effects
Hypogycemics- low FSBS
Levothyroxine - CNS aggitation, Tachicardia
Lithium - inc. R/F seizures |
|
|
Term
|
Definition
TCA
Drug interactions:
Alcohol - CNS dep.
Cogentin - Inc. anticholinergic effects
Hypogycemics- low FSBS
Levothyroxine - CNS aggitation, Tachicardia
Lithium - inc. R/F seizures |
|
|
Term
|
Definition
TCA
Drug interactions:
Alcohol - CNS dep.
Cogentin - Inc. anticholinergic effects
Hypogycemics- low FSBS
Levothyroxine - CNS aggitation, Tachicardia
Lithium - inc. R/F seizures |
|
|
Term
| TCA Over Dose: Signs and Symptoms |
|
Definition
Fatal in OD
CNS depression
Seizures
Resp. Arrest
Arrythmias (QRS prolongation, V-fib)
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|
|
Term
|
Definition
Cholinergic rebound if stoped abbruptly.
Tapper over days to weeks. |
|
|
Term
|
Definition
MAOI
(2nd or 3rd line treatment)
Avoid Aged cheeses or processed meats
Avoid OTC decongestants
Risk for Serotonin syndrome
Aways have a med holiday of 2weeks prior to initiation of MAOI or switching to other class
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|
|
Term
Selegiline
(Dermal Patch)
|
|
Definition
Indicated for Parkenson's
MAOI
(2nd or 3rd line treatment)
Avoid Aged cheeses or processed meats
Avoid OTC decongestants
Risk for Serotonin syndrome
Aways have a med holiday of 2weeks prior to initiation of MAOI or switching to other class
|
|
|
Term
|
Definition
MAOI
(2nd or 3rd line treatment)
Avoid Aged cheeses or processed meats
Avoid OTC decongestants
Risk for Serotonin syndrome
Aways have a med holiday of 2weeks prior to initiation of MAOI or switching to other class
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|
|
Term
|
Definition
SSRI
(1st choice)
Fewer interactions
R/F Seritonin syndrome if used with MAOI, avoid meds that increase seritonin
may cause weight loss
|
|
|
Term
|
Definition
SSRI
(1st choice)
Fewer interactions
R/F Seritonin syndrome if used with MAOI, avoid meds that increase seritonin
may cause weight loss |
|
|
Term
|
Definition
SSRI
(1st choice)
Fewer interactions
R/F Seritonin syndrome if used with MAOI, avoid meds that increase seritonin
may cause weight loss |
|
|
Term
|
Definition
SSRI
(1st choice)
Fewer interactions
R/F Seritonin syndrome if used with MAOI, avoid meds that increase seritonin
may cause weight loss |
|
|
Term
|
Definition
SSRI
(1st choice)
Fewer interactions
R/F Seritonin syndrome if used with MAOI, avoid meds that increase seritonin
may cause weight loss |
|
|
Term
|
Definition
SSRI
(1st choice)
Fewer interactions
R/F Seritonin syndrome if used with MAOI, avoid meds that increase seritonin
may cause weight loss |
|
|
Term
|
Definition
SNRI
(1st choice)
LIVER TOXIC
Approved for DM Neuropathy
Fewer interactions
R/F Seritonin syndrome if used with MAOI, avoid meds that increase seritonin
may cause weight loss |
|
|
Term
|
Definition
SNRI
(1st choice)
LIVER TOXIC
Approved for DM Neuropathy
Fewer interactions
R/F Seritonin syndrome if used with MAOI, avoid meds that increase seritonin
may cause weight loss
|
|
|
Term
|
Definition
Other Antidepressent
Inhibits breakdown of DA and NE
R/F SEIZURES
Side effects: Nervousness, H/A, Insomnia, dizziness
May improve sexual function
2nd line treatment for anxiety disorders |
|
|
Term
|
Definition
Triazolopyridines
Other Antidepressent
LIVER TOXIC - brand name off the market
Inhibits 5HT reuptake and blocks receptors
Does not cause Anticholinergic Effects
R/F Pripism |
|
|
Term
|
Definition
Triazolopyridines
Other Antidepressent
Inhibits 5HT reuptake and blocks receptors
Does not cause Anticholinergic Effects
Helps with insomnia
R/F Pripism |
|
|
Term
|
Definition
Tetracyclics
Increased NE & 5HT in synapse
Helps with anxiety
R/F: wt gain, constipation, asthma exacerbation |
|
|
Term
What is a good choice for someone with depression and chronic pain?
|
|
Definition
|
|
Term
What is a good choice for someone with Akathisia
(motor restlessness)? |
|
Definition
|
|
Term
|
Definition
Mood Stablizer
Contraindicated in prego and CRF
NSAID's will cause increase in Lithium
Body views Lithium as sodium, anything that increase retension of sodium will cause increase retension of Lithium. |
|
|
Term
Anxiety:
What is the first choice drugs?
|
|
Definition
SSRI's/ SNRI's
Escitalopam (GAD, Panic, Social)
Paroxetine (GAD, Panic, Social)
Venafaxine(GAD, Panic, Social)
Duloxetine (GAD, Panic)
Fluvoxamine (Social)
Sertraline (Social) |
|
|
Term
|
Definition
Benzodiazepine
Inhibits GABA
(2nd line for anxiety)
Side Effects: CNS dep., Impaired memory, sedation, ataxia
Withdraw causes: CNS aggitation, muscular irritability |
|
|
Term
|
Definition
Benzodiazepine
Inhibits GABA
(2nd line for anxiety)
Side Effects: CNS dep., Impaired memory, sedation, ataxia
Withdraw causes: CNS aggitation, muscular irritability |
|
|
Term
|
Definition
Benzodiazepine
Inhibits GABA
(2nd line for anxiety)
Side Effects: CNS dep., Impaired memory, sedation, ataxia
Withdraw causes: CNS aggitation, muscular irritability |
|
|
Term
|
Definition
Benzodiazepine
Inhibits GABA
(2nd line for anxiety)
Side Effects: CNS dep., Impaired memory, sedation, ataxia
Withdraw causes: CNS aggitation, muscular irritability |
|
|
Term
|
Definition
Benzodiazepine
Inhibits GABA
(2nd line for anxiety)
Side Effects: CNS dep., Impaired memory, sedation, ataxia
Withdraw causes: CNS aggitation, muscular irritability |
|
|
Term
|
Definition
Benzodiazepine
Inhibits GABA
(2nd line for anxiety)
Side Effects: CNS dep., Impaired memory, sedation, ataxia
Withdraw causes: CNS aggitation, muscular irritability
|
|
|
Term
|
Definition
Benzodiazepine
Inhibits GABA
(2nd line for anxiety)
Side Effects: CNS dep., Impaired memory, sedation, ataxia
Withdraw causes: CNS aggitation, muscular irritability |
|
|
Term
|
Definition
1st gen. Antipsycotic (Typical)
Side Effects: Anticholinergic effects, antihistaminic effects (sedation), Alpha Blockage (hypotension)
Increased risk for EPS and Tardive Dyskinesia |
|
|
Term
|
Definition
1st gen. Antipsycotic (Typical)
Side Effects: Anticholinergic effects, antihistaminic effects (sedation), Alpha Blockage (hypotension)
Increased risk for EPS and Tardive Dyskinesia |
|
|
Term
|
Definition
1st gen. Antipsycotic (Typical)
Side Effects: Anticholinergic effects, antihistaminic effects (sedation), Alpha Blockage (hypotension)
Increased risk for EPS, Seizures, and Tardive Dyskinesia |
|
|
Term
|
Definition
1st gen. Antipsycotic (Typical)
Side Effects: Anticholinergic effects, antihistaminic effects (sedation), Alpha Blockage (hypotension)
Increased risk for EPS, Seizures, and Tardive Dyskinesia |
|
|
Term
|
Definition
1st gen. Antipsycotic (Typical)
Side Effects: Anticholinergic effects, antihistaminic effects (sedation), Alpha Blockage (hypotension)
Increased risk for EPS, Seizures, ECG changes and Tardive Dyskinesia |
|
|
Term
|
Definition
2nd gen. Antipsycotic (atypical)
(Not a good choice)
Side Effects: Anticholinergic effects, antihistaminic effects (sedation), Alpha Blockage (hypotension),
ECG changes, weight gain, onset of DM
R/F agranulocytosis
|
|
|
Term
|
Definition
2nd gen. Antipsycotic (atypical)
(1st choice for schizophrenia)
Side Effects: antihistaminic effects (sedation), Alpha Blockage (hypotension),
Seizures
No anticholinergic effects
|
|
|
Term
|
Definition
2nd gen. Antipsycotic (atypical)
(1st choice for schizophrenia)
Side Effects: Anticholinergic effects, antihistaminic effects (sedation), Alpha Blockage (hypotension),
weight gain, onset of DM
R/F agranulocytosis
May increase neg. symptoms of schizophrenia |
|
|
Term
|
Definition
2nd gen. Antipsycotic (atypical)
(1st choice for schizophrenia)
Side Effects: Anticholinergic effects, antihistaminic effects (sedation), Alpha Blockage (hypotension)
Helpful with depression and neg. syptoms of schizophrenia |
|
|
Term
|
Definition
2nd gen. Antipsycotic (atypical)
(1st choice for schizophrenia)
Side Effects: Anticholinergic effects, antihistaminic effects (sedation), Alpha Blockage (hypotension),
ECG changes
|
|
|
Term
|
Definition
2nd gen. Antipsycotic (atypical)
(1st choice for schizophrenia)
Side Effects: Anticholinergic effects, antihistaminic effects (sedation), Alpha Blockage (hypotension),
min. weight gain |
|
|
Term
|
Definition
2nd gen. Antipsycotic (atypical)
(1st choice for schizophrenia)
Side Effects: Anticholinergic effects, antihistaminic effects (sedation), Alpha Blockage (hypotension),
|
|
|
Term
|
Definition
Antimuscarinics (prefered):
Benztropine, trihexyphenidyl
Antihistaminic:
Diphenhydramine
Benzodiazepines:
Lorazepam |
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