Term
|
Definition
| Hashimoto's thyroiditis (gross) |
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Term
|
Definition
| Hashimoto's thyroiditis (lymphoid infiltrates throughout thyroid parenchyma) |
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Term
|
Definition
| Hashimoto's thyroiditis (lymphoid infiltrates around atrophic follicles) (note transformation of follicular epithelium to Hurthle cells) |
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Term
|
Definition
| Hashimoto's thyroiditis (note germinal center) |
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Term
|
Definition
| Multinodular goiter of thyroid (gross) |
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Term
|
Definition
| Multinodular goiter of thyroid (note follicles of varying size and areas of fibrosis) |
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Term
|
Definition
| Multinodular goiter of thyroid (note degenerative changes of fibrosis and cystic change) |
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Term
|
Definition
| Multinodular goiter of thyroid (extensive hyalinization between follicles) |
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Term
|
Definition
| Multinodular goiter of thyroid after iodine therapy (papillary epithelial hyperplasia) |
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Term
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Definition
| Follicular adenoma of thyroid (gross) |
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Term
|
Definition
| Follicular ademona of thyroid (encompassing fibrous capsule) |
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Term
|
Definition
| Follicular ademona of thyroid (solid trabeculae and microfollicles) |
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Term
|
Definition
| Papillary carcinoma of thyroid (gross) |
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Term
|
Definition
| Papillary carcinoma of thyroid (note areas of dense fibrous stroma and area of normal thyroid next to carcinoma) |
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Term
|
Definition
| Papillary carcinoma of thyroid (papillae with fibrovascular core lined by neoplastic cells) |
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Term
|
Definition
| Papillary carcinoma of thyroid (fibrovascular core and cancer cells with cleared nuclei and nuclear overlapping) |
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Term
|
Definition
| Papillary carcinoma of thyroid (left) compared to normal thyroid (right) |
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Term
|
Definition
| Papillary carcinoma of thyroid (nuclear pseudoinclusion in center of field) (also note nuclear grooving) |
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Term
|
Definition
| Papillary carcinoma of thyroid FNA (grooved nuclei) |
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Term
|
Definition
| Papillary carcinoma of thyroid FNA (papillary structure with vascular core visible on one side) |
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Term
|
Definition
| Papillary carcinoma of thyroid (psammoma body-dark purple thing in right lower corner) |
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Term
|
Definition
| Metastatic papillary carcinoma of thyroid in lymph node (note dark purple psammoma bodies) |
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Term
|
Definition
| Adrenal cortical adenoma (gross) |
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Term
|
Definition
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Term
|
Definition
| adrenal cortical adenoma (note compressed rim of normal cortex at periphery on right) |
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Term
|
Definition
| adrenal cortical adenoma (compressed rim of normal cortex at top) |
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Term
|
Definition
| adrenal cortical adenoma (note normal adrenal cortex at top showing perpendicularly arranged trabeculae compared to adenoma at bottom with extensively vacuolated cells) |
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Term
|
Definition
| adrenal cortical adenoma (extensivley vacuolated cells and moderate degree of nuclear atypia-not indicative of malignancy) |
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Term
|
Definition
| Parathyroid adenoma (gross) |
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Term
|
Definition
| Parathyroid adenoma (compression of normal parathyroid (at bottom)) |
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Term
|
Definition
| Parathyroid adenoma (significant pleomorphism of nuclei-does not indicate malignancy) |
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Term
|
Definition
| Medullary carcinoma of thyroid (tumor cells (purplish) interspersed between follicles and infiltrating within dense fibrous stroma) |
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Term
|
Definition
| Medullary carcinoma of thyroid (small regular nuclei with rare mitoses) |
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Term
|
Definition
| Medullary carcinoma of thyroid (spindle shaped cells) |
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Term
|
Definition
| Medullary carcinoma of thyroid (spindle shaped tumor cells interspersed within dense fibrous stroma) |
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Term
|
Definition
| Medullary carcinoma of thyroid (EM of nucrosecretory granules) |
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Term
|
Definition
| Medullary carcinoma of thyroid (EM of amyloid fibrils) |
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Term
|
Definition
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Term
|
Definition
| Pheochromocytoma (well defined fibrous capsule separating tumor (top) and compressed renal cortex (bottom) |
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Term
|
Definition
| Pheochromocytoma (fibrous capsule separating tumor (top) and adrenal cortex (bottom) |
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Term
|
Definition
| Pheochromocytoma (note complete compression of normal adrenal cortex) |
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Term
|
Definition
| Pheochromocytoma (nesting of cells, fibrovascular stroma, and marked cellular variation) |
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Term
|
Definition
| Pheochromocytoma (multinucleated tumor giant cells are common) (chromaffin granules on EM) |
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Term
|
Definition
| Pituitary adenoma (nest of uniform cells with papillary architecture) |
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Term
|
Definition
| Pituitary adenoma (sheets and nests of uniform cells with papillary architecture) |
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Term
|
Definition
| Pituitary adenoma (nuclear pleomorphism and enlargement) |
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Term
|
Definition
| KUB: Radiopqaque 5 mm kidney stone |
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Term
|
Definition
| Kidney stone (abdominal CT without contrast showing stone in right renal pelvis) |
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Term
|
Definition
| Kidney stone with secondary hydronephrosis (dilation of collecting system with destruction and thinnging of parenchyma) |
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Term
|
Definition
| Clear cell RCC (US: mass in mid pole of R kidney) |
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Term
|
Definition
| Clear cell RCC on CT with contrast showing mass in right kidney with right renal vein involvement |
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Term
|
Definition
| Clear cell RCC (solid to cord-like growth of cells w ith abundant clear cytoplasm) |
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Term
|
Definition
| Clear cell RCC (clear cytoplasm) |
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Term
|
Definition
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Term
|
Definition
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Term
|
Definition
| Wilm's tumor on CT with contrast (mass replacing upper pole of left kidney) |
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Term
|
Definition
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Term
|
Definition
| Wilm's tumor with 3 components (blastema=blue/purple, mesenchymal (spindled fibroblastic-like), epithelial(primitive tubules and glom-like structures)) |
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Term
|
Definition
| Wilm's tumor (high power of blastema-prominent mitotic activity) |
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Term
|
Definition
| Wilm's tumor (note anaplasia (nuclear enlargement, hyperchromaticity and abnormal mitoses)-bad prognosis) |
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Term
|
Definition
| Wilm's tumor (necrosis (center)) |
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Term
|
Definition
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Term
|
Definition
| Wilm's tumor (epithelial-glomeruloid bodies) |
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Term
|
Definition
| Wilm's tumor (tubules apparent within blastemal tumor) |
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Term
|
Definition
| Wilm's tumor (high power of tubule in tumor) |
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Term
|
Definition
| Wilm's tumor mesenchymal tissue (spindled cell fibroblastic-like tissue) (lighter colored cells here) |
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Term
|
Definition
| Wilm's tumor (mesenchymal component) |
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Term
|
Definition
| Urothelial carcinoma causing bilateral hydronephrosis and thickening of bladder |
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Term
|
Definition
| Urothelial carcinoma (bilateral moderate hydronephrosis and hydroureter) |
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Term
|
Definition
| Urothelial carcinoma on scope |
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Term
|
Definition
| Urothelial carcinoma grade 2 (papillary appearance around central fibrovascular cores with loss of cell polarity) |
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Term
|
Definition
| Urothelial carcinoma grade 3 |
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Term
|
Definition
| Urothelial carcinoma grade 3 (poorly differentiated-loss of papillar appearance and now appear as solid sheets) (note marked pleomorphism and disarray) |
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Term
|
Definition
| Urothelial carcinoma grade 3 (poorly differentiated) |
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Term
|
Definition
| Urothelial carcinoma (gross) |
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Term
|
Definition
| Urothelial carcinoma (bladder with tumor invasion into detrusor mm) |
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Term
|
Definition
| Urothelial carcinoma extending between smooth mm bundles of detrusor mm |
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Term
|
Definition
| Urothelial carcinoma (infiltration of tumor between bundles of smooth mm) (note hyperchromatic nuclei, high chromatin, and irregular nuclear contours) |
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Term
|
Definition
| Invasive squamous cell carcinoma of bladder (note intercellular bridges, dyskerotic cells, and keratinocyte whorls) |
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Term
|
Definition
| AD PCKD on US (hypo-echoic cystic structures of various sizes) |
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Term
|
Definition
| AD PCKD on CT (multicystic masses of various sized cysts replacing bilateral kidneys with cysts in liver) |
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Term
|
Definition
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Term
|
Definition
| AD PCKD (gross hemisection) |
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Term
|
Definition
| AD PCKD (multiple cysts replacing normal parenchyma) |
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Term
|
Definition
| AD PCKD (cysts lined by thin, simple cuboidal epithelium) (surrounding parenchyma has severe interstitial fibrosis and tubular atrophy due to compression from cysts) |
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Term
|
Definition
| AD PCKD (severe interstitial fibrosis and tubular atrophy) |
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Term
|
Definition
|
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Term
|
Definition
| AR PCKD (numerous cysts located in radial fashoin perpendicular to kidney surface) |
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Term
|
Definition
| AR PCKD (numerous cysts located in radial fashion perpendicular to kidney surface) (note normal glom and tubular structures between cysts) |
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Term
|
Definition
| Congenital hepatic fibrosis as part of AR PCKD |
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Term
|
Definition
| Congenital hepatic fibrosis as part of AR PCKD (trichone stain for collagen) |
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