Term
| What origin are most tumors in the ovary? |
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Definition
Epithelial
*Germ cell tumors, and Stromal cell tumors |
|
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Term
| Which cancer is the most lethal in which 70% spread beyond pelvis at time of diagnosis? |
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Definition
|
|
Term
| What is the most important risk factor for ovarian cancer? |
|
Definition
Family Hx
*2 or more first degree relatives affected: 10-fold increase |
|
|
Term
| What is BRCA 1 associated with? |
|
Definition
| Earlier onset of breast cancer and overall lifetime breast cancer risk of 50-80% |
|
|
Term
| What is BRCA 2 associated with? |
|
Definition
| life time risk same as BRCA-1, not as early onset, and higher risk of male breast cancer and pancreatic cancer |
|
|
Term
| What age women is lynch syndrome II seen in? |
|
Definition
|
|
Term
| What is an important clinical feature of familial syndromes for ovarian cancer? |
|
Definition
| approximately 70% with advanced disease will spread to upper abdomen or pleural space |
|
|
Term
| What is the diagnostic imaging test that is used for ovarian cancer? |
|
Definition
|
|
Term
| What appearance do malignant ovarian masses usually have? |
|
Definition
| composed of both solid and cystic areas |
|
|
Term
| What is required for tissue diagnosis, staging, and dubulking in ovarian cancer? |
|
Definition
|
|
Term
| Why is Uterine cervical cancer uncommon in developed countries? |
|
Definition
| effectiveness of pap smears |
|
|
Term
| What are the most common types of HPV responsible for uterine cervical cancer? |
|
Definition
16, 18, 31, 33, and 35
*Approximately 70% from 16 and 18 |
|
|
Term
| Quadravalent vaccine (Gardisil) is effective against what HPV types? |
|
Definition
1) 16, 18 for Cancer
2) 6, 11 for warts |
|
|
Term
| What are the pap smear recommendations? |
|
Definition
| begin at 18 and then annually for 3 years, if normal for 3 years-clinician's discretion |
|
|
Term
| What is the most common type of cancer in uterine cervix cancer? |
|
Definition
|
|
Term
| Where do 90% of endometrial cancers evolve from? |
|
Definition
|
|
Term
| What is the most frequent tumor of the gynecological tract? |
|
Definition
|
|
Term
| What is the most common risk factor for uterine cancer and how? |
|
Definition
1) obesity
2) increased peripheral conversion of androstenedione to estrone |
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