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Glycolysis
Steps of glycolysis with products and enzymes
33
Biochemistry
Undergraduate 4
03/29/2013

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Cards

Term
What happens in step 1
Definition
phosphorylation of glucose
Term
Reactants/products in step 1
Definition
Glucose ---> glucose-6-phosphate
Term
enzymes/required molecules in step 1
Definition
hexokinase + Mg + ATP
Term
What happens in step 2
Definition
isomerization of glucose-6-phosphate
Term
Reactants/products in step 2
Definition
glucose-6-phosphate ---> fructose-6-phosphate
Term
enzymes/required molecules in step 2
Definition
glucose phosphate isomerase + phosphoglucose isomerase
Term
What happens in step 3
Definition
phosphorylation of fructose-6-phosphate
Term
Reactants/products in step 3
Definition
fructose-6-phosphate ---> fructose-1,6-bisphosphate
Term
enzymes/required molecules in step 3
Definition
Mg + ATP + phosphofructokinase (allosteric enzyme)
Term
What happens in step 4
Definition
cleavage of fructose-1,6-bisphosphate
Term
Reactants/products in step 4
Definition
fructose-1,6-bisphosphate ---> glyceraldehyde-3-phosphate + dihydroxyacetone phosphate
Term
enzymes/required molecules in step 4
Definition
aldolase
Term
What happens in step 5
Definition
isomerization of dihydroxyacetone phosphate (fast step, almost immediate)
Term
Reactants/products in step 5
Definition
dihydroxyacetone phosphate ---> glyceraldehyde-3-phosphate
Term
enzymes/required molecules in step 5
Definition
triosephosphate isomerase
Term
What steps make up Phase 1
Definition
steps 1-5
Term
How many times does Phase 1 occur
Definition
Twice
Term
What happens in step 6
Definition
oxidation of glyceraldehyde-3-phosphate (only oxidation step)
Term
Reactants/products in step 6
Definition
glyceraldehyde-3-phosphate + NADH ---> 1,3-bisphosphoglycerate + ATP
Term
enzymes/required molecules in step 6
Definition
Mg + ADP + kinase
Term
What happens in step 7
Definition
transfer of phosphate from 1,3-bisphosphoglycerate
Term
Reactants/products in step 7
Definition
1,3-bisphosphoglycerate ---> 3-phosphoglycerate
Term
enzymes/required molecules in step 7
Definition
Mg + phosphoglycerate kinase + ADP
Term
What happens in step 8
Definition
isomerization of 3-phosphoglycerate
Term
Reactants/products in step 8
Definition
3-phosphoglycerate ---> 2-phosphoglycerate
Term
enzymes/required molecules in step 8
Definition
phosphoglyceromutase
Term
what happens in step 9
Definition
dehydration of 2-phosphoglycerate
Term
reactants/products in step 9
Definition
2-phosphoglycerate ---> phosphoenolpyruvate
Term
enzymes/required molecules in step 9
Definition
enolase
Term
what happens in step 10
Definition
transfer a phosphate group to ADP from phosphoenolpyruvate
Term
reactants/products in step 10
Definition
phosphoenolpyruvate + ADP ---> Pyruvate + ATP
Term
enzymes/required molecules in step 10
Definition
pyruvate kinase + ADP + Mg
Term
How many of the main reactants and products are there in each step of the 2nd phase
Definition
two, as a result of going through phase 1 twice
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