Term
| SUPEPITHELIAL IgG/C3 DEPOSITS |
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Definition
| MEMBRANOUS GLOMERULOPATHY |
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Term
| NEPHROTIC SYNDROME WITH DEPOSITS IN BASEMENT MEMBRANE |
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Definition
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Term
| NEPHROTIC SYNDROME WITH SUBENDOTHELIAL DEPOSISTS OF IgG AND C3; C1Q AND c4 |
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Definition
| MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS |
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Term
| NEPHROTIC WITH INJURY TO PODOCYTES |
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Definition
MINIMAL CHANGE OR FSGS
MINIMAL CHANGE= DIFFUSE FOOT PROCESS FUSION
FSGS= PATCHY FOOT PROCESS FUSION |
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Term
| 25Y.O. MAN WITH RECURRENT EPISODES OF HEMATURIA. EACH ASSOCIATED WITH A URI. DIPSTICK 2+ PROTEIN AND + FOR BLOOD... DIAGNOSIS AND BIOPSY |
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Definition
IGA NEPHROPATHY HAS MILD- MODERATE PROTEINURIA, MICROSOCPIC HEMATURIA
OFTEN ASSOCIATED WITH RESPIRATORY OR GI INFECTION IN 20'S MALE... IGA AND C3 IN MESANGIUM |
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Term
| normal SERUM COMPLEMENT IN WHICH DISEASES? |
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Definition
vASCULITIS (WEGNER'S PAN, GOODPASTURES AND anti-GBM)
IGa NEPHROPATHY
HENOCH-SCHONLEIN PURPURA (SKIN)
HEREDITARY NEPHRITIS (DEAF) |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
Anti-GBM nephritis
GOODPASTEURS IF PULMONARY HEMMORAGE |
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Term
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Definition
AntiMPO or AntiPR3 + systemic symptoms = MICROSCOPIC POLYANGITIS (pANCA)
AntiMPO or AntiPR3 + midline symptoms= WEGNER'S (NOTE cANCA)
AntiMPO or AntiPR3 + no systemic symptoms= renal vasculitis (NOTE PAUCI IMMUNE AND IDIOPATHIC CRESCENTIC RENAL VASCULITIS ARE BASICALLY THE SAME ACCORDING TO ROBBINS) pANCA |
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Term
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Definition
Antibodies against the GBM (in situ binding)
(type I).
Immune complex formation and complement activation in mesangium or subendothelial space (type II).
T-cell mediated immunity with or without circulating antibodies against neutrophilic cytoplasmic antigens (ANCA) (type III). |
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Term
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Definition
| MINIMAL CHANGE OR CHRONIC GN |
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Term
| YOUNG WOMAN WITH PHOTOSENSITIVE SKIN LESIONS AND ARTHRLAGIAS |
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Definition
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Term
| WHICH IS INFLAMATORY- NEPHROTIC OR NEPHRITIC |
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Definition
| NEPHRITIC... + INFLAMATORY GLOMERULUS |
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Term
| NEPHRITIC WITH IC FORMATION, COMPLEMENT ACTIVATION IN MESANGIUM OR SUBENDOTHELIAL SPACE |
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Definition
| IGA NEPH... POST STREP, OR LUPUS |
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Term
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Definition
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Term
| UA WITH HIGHLY SELECTIVE PROTEINURIA... ALBUMIN AND OTHER LMW PROTIES |
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Definition
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Term
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Definition
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Term
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Definition
PIGN
SLE
MEMBRANOUS GLOMERULOPATHY |
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Term
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Definition
REFLUX NEPHROPATHY
CONGENITAL UNILATERAL KIDNEY
IV DRUG ABUSE
HIV |
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Term
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Definition
| TYPE I DENSE DEPOSIT MPGN |
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Term
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Definition
| OFTEN ASSOCIATED WITH BPGN |
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Term
| KEY HISTOLOGIC FEATURE OF NEPHRITIC SYNDROME |
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Definition
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Term
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Definition
Focal (<50% of glomeruli are involved)
Diffuse (most severe form, most glomeruli are involved)
Mesangial proliferation (milder form)
The capillary wall remains intact. |
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Term
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Definition
Crescent formation in >50% of glomeruli
The capillary wall is breached. |
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