Term
|
Definition
|
|
Term
| 1st line glaucoma treatment |
|
Definition
| beta blockers, prostaglandin analogs, brimonidine, topical carbonic anhydrase inhibitors |
|
|
Term
| 2nd line glaucoma treatment |
|
Definition
| pilocarpine, apraclonidine |
|
|
Term
| 3rd line glaucoma treatment |
|
Definition
| carbachol, oral carbonic anhydrase inhibitors, echothiophate |
|
|
Term
|
Definition
| betaxolol, carteolol, levobunolol, metipranolol, timolol |
|
|
Term
|
Definition
| decrease production of aqueous humor |
|
|
Term
|
Definition
| systemic absorption, pulmonary (asthma, COPD), CV (bradycardia, congestive heart failure), diabetes |
|
|
Term
| Beta blockers systemic side effects |
|
Definition
| bronchospasm, CHF, bradycardia, hypotension, depression, lethargy, sexual dysfunction, increased cholesterol and triglycerides, mask hypoglycemia symptoms and reduced glucose tolerance in pts with diabetes |
|
|
Term
| Beta Blockers Ocular Side effects |
|
Definition
| stinging, dry eyes, blepharitis |
|
|
Term
| Beta Blockers (ocular) interactions |
|
Definition
| oral beta blockers, calcium channel blockers, quinidine |
|
|
Term
| Synthetic prostaglandin F2alpha analogue |
|
Definition
| Latanoprost, Tafluprost, Travoprost |
|
|
Term
| Synthetic prostamide analogue |
|
Definition
|
|
Term
|
Definition
|
|
Term
| increased uveoscleral outflow; increased trabecular outflow |
|
Definition
|
|
Term
|
Definition
| 1st line; reduce IOP 25-35% |
|
|
Term
| Prostaglandin Analogues Cautions |
|
Definition
| hypersensitivity, macular edema, ocular inflammation, preganancy |
|
|
Term
| ocular side effects (prostaglandin analogues) |
|
Definition
| hyperemia, darkening pigment, eyelash lengthening/thickening |
|
|
Term
| Bimatoprost (latisse, Allergan) Common ADRs |
|
Definition
| Eye pruritus, conjunctival hyperemia, skin hyperpigmentation |
|
|
Term
| Adrenergic Agonists- Selective |
|
Definition
|
|
Term
|
Definition
| first line- reduces IOP 18-27% at peak and 10% at 8-12 hours |
|
|
Term
|
Definition
|
|
Term
| Brimonidine Systemic side effects |
|
Definition
| lethargy, dry mouth/nose, reduced blood pressure |
|
|
Term
| Brimonidine Ocular side effects |
|
Definition
|
|
Term
| Apraclonidine cautions/SE |
|
Definition
| tachyphylaxis and ocular allergy |
|
|
Term
| Carbonic anhydrase inhibitors |
|
Definition
| Brinzolamide, Dorzolamide and Timiolol |
|
|
Term
| Carbonic anhydrase inhibitors |
|
Definition
| First line; reduce IOP 15-26% |
|
|
Term
| carbonic anhydrase inhibitors cautions |
|
Definition
| systemic effects, sulfonamide allergy |
|
|
Term
| carbonic anhydrase inhibitors systemic side effects |
|
Definition
| bitter taste, headache, nausea, fatigue |
|
|
Term
| carbonic anhydrase inhibitors ocular side effects |
|
Definition
| blurred vision, stinging, ocular allergic reactions |
|
|
Term
| Cholinergic Agonists Direct Acting |
|
Definition
| Carbachol and pilocarpine |
|
|
Term
| increased trabecular outflow |
|
Definition
| cholinergic agonists direct acting |
|
|
Term
|
Definition
| second line- reduces IOP 20-30% |
|
|
Term
| Cholinergic Agonists Direct Acting Cautions and systemic side effects |
|
Definition
| Miosis; headache, salivation, diarrhea, sweating, flushing |
|
|
Term
| Cholinergic Agonists Direct Acting Ocular side effects |
|
Definition
| myopia, brow pain, accommodative spasm |
|
|
Term
| Cholinesterase Inhibitors |
|
Definition
|
|
Term
| increased trabecular outflow |
|
Definition
|
|
Term
|
Definition
| systemic effects, uveal inflammation, cataracts |
|
|
Term
| echothiophate systemic side effects |
|
Definition
| n/v/d, cramps, sweating, salivation, urinary incontinence |
|
|
Term
| echothiophate ocular side effects |
|
Definition
| burning, tearing, myopia, cataracts, iris cysts, brow pain, lid muscle twitching, conjunctival and ciliary redness |
|
|
Term
|
Definition
| 5-fluorouracil, Mitomycin (mitosol) |
|
|
Term
| primary open-angle glaucoma symptoms |
|
Definition
| usually none, occasionally headache and tired eyes |
|
|
Term
|
Definition
| ophthalmic corticosteroids, systemic corticosteroids, inhaled/intranasal corticosteroids, fenoldopam, ophthalmic anticholinergics |
|
|
